Search Results - "Chadwick, E."

Benthic community structure on coral reefs exposed to intensive recreational snorkeling by Renfro, Bobbie, Chadwick, Nanette E

“…Chronic anthropogenic disturbances on coral reefs in the form of overfishing and pollution can shift benthic community composition away from stony corals and…”
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Bacterial Associates of Two Caribbean Coral Species Reveal Species-Specific Distribution and Geographic Variability by MORROW, Kathleen M, MOSS, Anthony G, CHADWICK, Nanette E, LILES, Mark R

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models by Weaver, Richard J., Blomme, Eric A., Chadwick, Amy E., Copple, Ian M., Gerets, Helga H. J., Goldring, Christopher E., Guillouzo, Andre, Hewitt, Philip G., Ingelman-Sundberg, Magnus, Jensen, Klaus Gjervig, Juhila, Satu, Klingmüller, Ursula, Labbe, Gilles, Liguori, Michael J., Lovatt, Cerys A., Morgan, Paul, Naisbitt, Dean J., Pieters, Raymond H. H., Snoeys, Jan, van de Water, Bob, Williams, Dominic P., Park, B. Kevin

“…Drug-induced liver injury (DILI) is a patient-specific, temporal, multifactorial pathophysiological process that cannot yet be recapitulated in a single in…”
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Development of a comprehensive musculoskeletal model of the shoulder and elbow by Asadi Nikooyan, A., Veeger, H. E. J., Chadwick, E. K. J., Praagman, M., van der Helm, F. C. T.

“…The Delft Shoulder and Elbow Model (DSEM), a musculoskeletal model of the shoulder and elbow has been extensively developed since its introduction in 1994…”
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Bladder trigone sparing radiotherapy in prostate cancer treatment by Chetiyawardana, G., Chadwick, E., Kordolaimi, S., Sundar, S.

“…Evidence suggests the bladder trigone to be a potential organ at risk (OAR) in predicting acute and late genitourinary (GU) side effects when treating prostate…”
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The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death by Kamalian, Laleh, Chadwick, Amy E., Bayliss, Mark, French, Neil S., Monshouwer, Mario, Snoeys, Jan, Park, B. Kevin

“…•Short substitution of glucose with galactose in HepG2 media reveals mito-toxicity.•Parallel ATP/cytotoxicity measurement provides a mitochondrial functional…”
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Persistent pollutants exceed toxic thresholds in a freshwater top predator decades after legislative control by Kean, E.F., Shore, R.F., Scholey, G., Strachan, R., Chadwick, E.A.

“…Declining emissions of persistent organic pollutants (POPs), subject to international control under the Stockholm convention, are not consistently reflected in…”
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Technical note: Understanding the effect of COVID-19 on particle pollution using a low-cost sensor network by Chadwick, E., Le, K., Pei, Z., Sayahi, T., Rapp, C., Butterfield, A.E., Kelly, K.E.

“…The 2020 coronavirus pandemic and the following quarantine measures have led to significant changes in daily life worldwide. Preliminary research indicates…”
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Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile by Heslop, James A., Rowe, Cliff, Walsh, Joanne, Sison-Young, Rowena, Jenkins, Roz, Kamalian, Laleh, Kia, Richard, Hay, David, Jones, Robert P., Malik, Hassan Z., Fenwick, Stephen, Chadwick, Amy E., Mills, John, Kitteringham, Neil R., Goldring, Chris E. P., Kevin Park, B.

“…The application of primary human hepatocytes following isolation from human tissue is well accepted to be compromised by the process of dedifferentiation. This…”
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Bioenergetic profile of human coronary artery smooth muscle cells and effect of metabolic intervention by Yang, Mingming, Chadwick, Amy E, Dart, Caroline, Kamishima, Tomoko, Quayle, John M

“…Bioenergetics of artery smooth muscle cells is critical in cardiovascular health and disease. An acute rise in metabolic demand causes vasodilation in systemic…”
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Population dynamics of corkscrew sea anemones Bartholomea annulata in the Florida Keys by O’Reilly, Erin E., Chadwick, Nanette E.

“…Corkscrew sea anemones Bartholomea annulata are important ecologically as hubs of a mutualistic network involving cleaner shrimps and client fishes on…”
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The unprecedented 2012 outburst of SN 2009ip: a luminous blue variable star becomes a true supernova by Mauerhan, Jon C., Smith, Nathan, Filippenko, Alexei V., Blanchard, Kyle B., Blanchard, Peter K., Casper, Chadwick F. E., Cenko, S. Bradley, Clubb, Kelsey I., Cohen, Daniel P., Fuller, Kiera L., Li, Gary Z., Silverman, Jeffrey M.

“…Some reports of supernova (SN) discoveries turn out not to be true core-collapse explosions. One such case was SN 2009ip, which was recognized to be the…”
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Gambling on hunger? The right to adequate food and commodity derivatives trading by Chadwick, Anna E

“…Non-governmental organizations (NGOs) have claimed that financial speculators, by gambling on food prices via commodity derivative instruments, contributed to…”
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The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review by Jones, Samantha W, Ball, Amy L, Chadwick, Amy E, Alfirevic, Ana

“…The triad of drug efficacy, toxicity and resistance underpins the risk-benefit balance of all therapeutics. The application of pharmacogenomics has the…”
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Differential toxic effects of bile acid mixtures in isolated mitochondria and physiologically relevant HepaRG cells by Penman, Sophie L., Sharma, Parveen, Aerts, Hélène, Park, B. Kevin, Weaver, Richard J., Chadwick, Amy E.

“…Bile acids (BAs) are recognised as the causative agents of toxicity in drug-induced cholestasis (DIC). Research in isolated mitochondria and HepG2 cells have…”
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Using the health belief model to identify communication opportunities to prevent Chagas disease in Southern Ecuador by Patterson, Nelson M, Bates, Benjamin R, Chadwick, Amy E, Nieto-Sanchez, Claudia, Grijalva, Mario J

“…Chagas disease (CD) is a life-threatening illness caused by the protozoan parasite Trypanosoma cruzi, which is transmitted by triatomine bugs. Triatomine bugs…”
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Developing In Vitro Models to Define the Role of Direct Mitochondrial Toxicity in Frequently Reported Drug-Induced Rhabdomyolysis by Bin Dayel, Faten F, Alfirevic, Ana, Chadwick, Amy E

“…The United States Food and Drug Administration Adverse Event Reporting System (FAERS) logged 27,140 rhabdomyolysis cases from 2004 to 31 March 2020. We used…”
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Exposure of human immune cells, to the antiretrovirals efavirenz and lopinavir, leads to lower glucose uptake and altered bioenergetic cell profiles through interactions with SLC2A1 by Heaton, Bethany J., Jensen, Rebecca L., Line, James, David, Christopher A.W., Brain, Danielle E., Chadwick, Amy E., Liptrott, Neill J.

“…SLC2A1 mediates glucose cellular uptake; key to appropriate immune function. Our previous work has shown efavirenz and lopinavir exposure inhibits T cell and…”
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The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury by Ball, Amy Louise, Jolly, Carol E, Lennon, Mark G, Lyon, Jonathan J, Alfirevic, Ana, Chadwick, Amy E

“…Evidence supports an important link between mitochondrial DNA (mtDNA) variation and adverse drug reactions such as idiosyncratic drug-induced liver injury…”
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Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture by Kelly, Ross A, Leedale, Joseph, Harrell, Andy, Beard, Daniel A, Randle, Laura E, Chadwick, Amy E, Webb, Steven D

“…Cancer cells depend on glucose metabolism via glycolysis as a primary energy source, despite the presence of oxygen and fully functioning mitochondria, in…”
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