Search Results - "Chacon, Jessica"

Systematic analysis of CD39, CD103, CD137, and PD‐1 as biomarkers for naturally occurring tumor antigen‐specific TILs by Eiva, Monika A., Omran, Dalia K., Chacon, Jessica A., Powell, Daniel J.

“…The detection of tumor‐specific T cells in solid tumors is integral to interrogate endogenous antitumor responses and to advance downstream therapeutic…”
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Peptide Drug Conjugates and Their Role in Cancer Therapy by Heh, Ethan, Allen, Jesse, Ramirez, Fabiola, Lovasz, Daniel, Fernandez, Lorena, Hogg, Tanis, Riva, Hannah, Holland, Nathan, Chacon, Jessica

“…Drug conjugates have become a significant focus of research in the field of targeted medicine for cancer treatments. Peptide-drug conjugates (PDCs), a subset…”
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Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy by Chacon, Jessica Ann, Wu, Richard C, Sukhumalchandra, Pariya, Molldrem, Jeffrey J, Sarnaik, Amod, Pilon-Thomas, Shari, Weber, Jeffrey, Hwu, Patrick, Radvanyi, Laszlo

“…Adoptive T-cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL) can induce tumor regression in up to 50% or more of patients with unresectable…”
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Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level by Song, De-Gang, Ye, Qunrui, Poussin, Mathilde, Chacon, Jessica A, Figini, Mariangela, Powell, Jr, Daniel J

“…The poor prognosis and the limited efficacy of targeted therapy in patients with triple-negative breast cancer (TNBC) have raised the need for alternative…”
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Specific Lymphocyte Subsets Predict Response to Adoptive Cell Therapy Using Expanded Autologous Tumor-Infiltrating Lymphocytes in Metastatic Melanoma Patients by RADVANYI, Laszlo G, BERNATCHEZ, Chantale, GLASS, Michelle, JOHNSON, Valen E, MCMANNIS, John D, SHPALL, Elizabeth, PRIETO, Victor, PAPADOPOULOS, Nicholas, KIM, Kevin, HOMSI, Jade, BEDIKIAN, Agop, HWU, Wen-Jen, MINYING ZHANG, PATEL, Sapna, ROSS, Merrick I, LEE, Jeffrey E, GERSHENWALD, Jeffrey E, LUCCI, Anthony, ROYAL, Richard, CORMIER, Janice N, DAVIES, Michael A, MANSARAY, Rahmatu, FULBRIGHT, Orenthial J, FOX, Patricia S, TOTH, Christopher, RAMACHANDRAN, Renjith, WARDELL, Seth, GONZALEZ, Audrey, HWU, Patrick, MILLER, Priscilla, CHACON, Jessica, WU, Richard, LIZEE, Gregory, MAHONEY, Sandy, ALVARADO, Gladys

“…Adoptive cell therapy (ACT) using autologous tumor-infiltrating lymphocytes (TIL) is a promising treatment for metastatic melanoma unresponsive to conventional…”
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Teaching Critical Thinking and Problem-Solving Skills to Healthcare Professionals by Chacon, Jessica A., Janssen, Herb

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Mycobacterium smegmatis secreting methionine sulfoxide reductase A (MsrA) modulates cellular processes in mouse macrophages by Veerapandian, Raja, Ramos, Enrique I., Vijayaraghavan, Mahalakshmi, Sedano, Melina J., Carmona, Areanna, Chacon, Jessica A., Gadad, Shrikanth S., Dhandayuthapani, Subramanian

“…Methionine sulfoxide reductase A (MsrA) is an antioxidant repair enzyme that reduces the oxidized methionine (Met-O) in proteins to methionine (Met). Its…”
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The Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor Efficacy by Chacon, Jessica Ann, Schutsky, Keith, Powell, Daniel J

“…Genomic destabilizers, such as radiation and chemotherapy, and epigenetic modifiers are used for the treatment of cancer due to their apoptotic effects on the…”
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Sending a Message: Use of mRNA Vaccines to Target the Tumor Immune Microenvironment by Ramirez, Fabiola, Zambrano, Angelica, Hennis, Robert, Holland, Nathan, Lakshmanaswamy, Rajkumar, Chacon, Jessica

“…While cancer immunotherapies have become central to treatment, challenges associated with the ability of tumors to evade the immune system remain significant…”
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Pathogenic mycoplasmas of humans regulate the long noncoding RNAs in epithelial cells by Ramos, Enrique I., Veerapandian, Raja, Das, Kishore, Chacon, Jessica A., Gadad, Shrikanth S., Dhandayuthapani, Subramanian

“…Non-coding RNAs (ncRNAs), specifically long ncRNAs (lncRNAs), regulate cellular processes by affecting gene expression at the transcriptional,…”
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Exploration of the integration of microbiology and immunology emerging topics into undergraduate medical education by Bauer, Margaret E, Akbar, Samina, Bauler, Timothy J, Chacon, Jessica, McClelland, Erin E, Staudaher, Shawn, Zhao, Yuan

“…Medical school educators face challenges determining which new and emerging topics to incorporate into medical school curricula, and how to do so. A study was…”
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4-1BB-Enhanced Expansion of CD8 + TIL from Triple-Negative Breast Cancer Unveils Mutation-Specific CD8 + T Cells by Harao, Michiko, Forget, Marie-Andrée, Roszik, Jason, Gao, Hui, Babiera, Gildy V, Krishnamurthy, Savitri, Chacon, Jessica A, Li, Shumin, Mittendorf, Elizabeth A, DeSnyder, Sarah M, Rockwood, Korrene F, Bernatchez, Chantale, Ueno, Naoto T, Radvanyi, Laszlo G, Vence, Luis, Haymaker, Cara, Reuben, James M

“…Triple-negative breast cancer (TNBC) highly infiltrated with CD8 tumor-infiltrating lymphocytes (TIL) has been associated with improved prognosis. This…”
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Harnessing the Immune System with Cancer Vaccines: From Prevention to Therapeutics by Le, Ilene, Dhandayuthapani, Subramanian, Chacon, Jessica, Eiring, Anna M, Gadad, Shrikanth S

“…Prophylactic vaccination against infectious diseases is one of the most successful public health measures of our lifetime. More recently, therapeutic…”
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Personalized Medicine in Undergraduate Medical Education: a Spiral Learning Model by Chacon, Jessica A., Cervantes, Jorge L., Perry, Cynthia N., Pfarr, Curt M., Ayoubieh, Houriya

“…Educational strategies to introduce medical students to scientific advances are needed as evidence continues to evolve regarding their clinical application in…”
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Closing the digital divide: Developing a platform to conduct training, outreach, and education for employment skills by Johnson, Sarah, Allen, Jesse, Fernandez, Lorena, Garikiparthy, Veeravenkata, Renovato, Laura, Land, Maria, Favela, Leticia, Becerra, Karina, Belmares, Ricardo, Holland, Nathan, Chacon, Jessica

“…El Paso, Texas, like many communities along the United States/Mexico border, suffers from a lack of access to many social determinants of health, especially in…”
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Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype by WU, Richard C, SHUJUAN LIU, LIZEE, Gregory, RADVANYI, Laszlo G, CHACON, Jessica A, SHENG WU, YUFENG LI, SUKHUMALCHANDRA, Pariya, MURRAY, James L, MOLLDREM, Jeffrey J, HWU, Patrick, PIRCHER, Hanspeter

“…Tumor-specific T cells are frequently induced naturally in melanoma patients and infiltrate tumors. It is enigmatic why these patients fail to experience tumor…”
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Implications of Enhancer Transcription and eRNAs in Cancer by Adhikary, Santanu, Roy, Siddhartha, Chacon, Jessica, Gadad, Shrikanth S, Das, Chandrima

“…Despite extensive progress in developing anticancer therapies, therapy resistance remains a major challenge that promotes disease relapse. The changes that…”
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Abstract 796: Investigating incidence and survival patterns of cutaneous malignant melanoma in the United States from 2006-2017 by Kye, Yae, Alvarado, Luis, Dwivedi, Alok, Chacon, Jessica

“…Introduction: Skin cancers are one of the most common cancers in the United States with melanoma being the fifth leading cause of cancer. Despite its…”
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Correction: Immunotherapy Treatment Disparities: A Texas Cancer Registry Analysis of Patients with Cutaneous Melanoma by Ramirez, Fabiola, Alvarado, Luis, Dwivedi, Alok, Chacon, Jessica

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Understanding the Association Between Social Determinants of Health and Receipt of Immunotherapy for Melanoma by Ramirez, Fabiola, Vasquez, Rebecca, Gill, Jennifer, Riva, Hannah, Zambrano, Angelica, Samaniego, Michelle, Fernandez, Lorena, Chacon, Jessica

“…In this review article, we sought to elucidate how the social determinants of health, including socioeconomic status, education, neighborhood or physical…”
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