Search Results - "Cha, Soungchul"
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Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice
Published in Nature medicine (01-06-2014)“…Using an adapted competitive peptide phage display platform, Hong Qin and colleagues identify new candidate peptides specifically binding myeloid-derived…”
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Novel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo
Published in Clinical cancer research (01-03-2018)“…mAbs such as anti-CD20 rituximab are proven therapies in B-cell malignancies, yet many patients develop resistance. Novel therapies against alternative targets…”
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Early Intervention and Favorable Biologic Effects of Personalized Neoantigen Vaccines on the Tumor Immune Microenvironment in Smoldering Waldenstrom Macroglobulinemia
Published in Blood (02-11-2023)“…Lymphoplasmacytic lymphoma (LPL) is an incurable low-grade B-cell lymphoma, characterized by the presence of clonal tumor cells infiltrating the bone marrow…”
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CD19/BAFF-R dual-targeted CAR T cells for the treatment of mixed antigen-negative variants of acute lymphoblastic leukemia
Published in Leukemia (01-04-2022)“…Chimeric antigen receptor (CAR) T cells targeting CD19 mediate potent antitumor effects in B-cell malignancies including acute lymphoblastic leukemia (ALL),…”
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Phase I trial of a novel DNA vaccine in patients (pts) with smoldering Waldenstrom macroglobulinemia (sWM)
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 8050 Background: Idiotypic determinants of the surface immunoglobulin (Ig) associated with a given pt’s B-cell lymphoma are unique to that tumor,…”
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Abstract 2891: Bench-to-bedside development of a novel idiotype vaccine against lymphoma
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract Available therapies for lymphoplasmacytic lymphoma (LPL) provide no survival advantage if started before symptoms of end organ damage develop. Current…”
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Generation of a novel therapeutic peptide that depletes MDSC in tumor-bearing mice
Published in Nature medicine (25-05-2014)“…Cancer immune evasion is an emerging hallmark of disease progression. Functional studies to understand the role of myeloid-derived suppressor cells (MDSC) in…”
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