Search Results - "Cha, Mi Young"

Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy by Koh, Minseob, Park, Jongmin, Koo, Ja Young, Lim, Donghyun, Cha, Mi Young, Jo, Ala, Choi, Jang Hyun, Park, Seung Bum

“…Small‐molecule glucose uptake enhancers targeted to myotubes and adipocytes were developed through a phenotypic screening linked with target identification and…”
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Discovery of A Novel Her-1/Her-2 Dual Tyrosine Kinase Inhibitor for the Treatment of Her-1 Selective Inhibitor-Resistant Non-small Cell Lung Cancer by Cha, Mi Young, Lee, Kwang-Ok, Kim, Jong Woo, Lee, Chang Gon, Song, Ji Yeon, Kim, Young Hoon, Lee, Gwan Sun, Park, Seung Bum, Kim, Maeng Sup

“…A novel series of (S)-1-acryloyl-N-[4-(arylamino)-7-(alkoxy)quinazolin-6-yl]pyrrolidine-2-carboxamides were synthesized and evaluated as Her-1/Her-2 dual…”
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Characterization of Microbial Decay and Microbial Communities in Waterlogged Archaeological Rosewood (Dalbergia Species) by Jong Sik Kim, Minseok Kim, Ju Won Lim, Mi Young Cha, Kwang Ho Lee, Yong Hee Yoon, Yoon Soo Kim

“…While numerous studies have examined microbial attacks on waterlogged archaeological wood, limited information is available regarding microbial attacks in…”
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Antitumor activity of HM781-36B, a highly effective pan-HER inhibitor in erlotinib-resistant NSCLC and other EGFR-dependent cancer models by Cha, Mi Young, Lee, Kwang-Ok, Kim, Mira, Song, Ji Yeon, Lee, Kyu Hang, Park, Jongmin, Chae, Yun Jung, Kim, Young Hoon, Suh, Kwee Hyun, Lee, Gwan Sun, Park, Seung Bum, Kim, Maeng Sup

“…The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases has been implicated in a variety of cancers. In particular, activating…”
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유아교육기관의 환경보전 부모교육프로그램 효과연구 by 최경순(Kyung Sun Choi), 차미영(Mi Young Cha)

“…Training for mothers and children first included information on water, ground, and air pollution, saving energy, and reducing trash. In the second phase, the…”
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Abstract 688: Anti-CNTN4 antibody, GENA-104A07 suppresses tumor growth in murine syngeneic tumor models by regulating T cell function by Cha, Mi Young, Houh, Youn Kyung, Kim, Yun Yeon, Kim, Hyunuk, Chung, Joo-Yeon, Park, Kyung Mi, Park, Hansoo

“…Abstract Vast improvements in tumor treatment have been achieved with immune checkpoint inhibitors. They have been approved for use in monotherapy or…”
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Abstract 492: CNTN4 is a novel immune checkpoint protein that inhibits proliferation of T cell by interacting with APP by Cha, Mi Young, Jeon, Bu-Nam, Jeong, Areum, Chung, Joo-Yeon, Yang, Hyunsuk, Park, Kyung Mi, Park, Hansoo

“…Abstract Contactin 4 (CNTN4, alias BIG-2) is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as cell adhesion, playing a…”
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Abstract 6382: Activation of transcription factors, p65 and NFATc1, mediated by WNT5a, induces up-regulation of novel immune checkpoint CNTN4 expression by Cha, Mi Young, Jeon, Bu-Nam, Kang, Hyeokgu, Park, Kyung Mi, Park, Hansoo

“…Abstract We previously confirmed that contactin 4 (CNTN4) is highly expressed in the various human tumor tissues and inhibits mouse and human T cell activity…”
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Abstract 7522: Association between the CNTN4 expression and responsiveness to pembrolizumab in gastric cancer by Cha, Mi Young, Kim, Gihyeon, Park, Changho, Jeon, Bu-Nam, Park, Kyung Mi, Park, Hansoo, Ock, Chan-Young

“…Abstract Even though numerous strategies for controlling malignant tumors have been established with immunotherapies, a solution for non-favorable responses to…”
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Abstract 580: APP as a novel immune checkpoint: Expression in T cells and its clinical implications for immuno-oncology drug refractory by Cha, Mi Young, Jeon, Bu-Nam, Kim, Gihyeon, Jeong, Areum, Park, Sang-Moo, Park, Kyung Mi, Park, Hansoo

“…Abstract Amyloid precursor protein (APP) is a type I transmembrane protein expressed in various cell types and tissues. We previously confirmed that APP…”
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Abstract 740: CNTN4 as a novel target for solid cancer with antibody-drug conjugate by Cha, Mi Young, Kim, Hyunuk, Byun, Seungmin, Ha, Youngeun, Park, Kitae, Yu, Hyunkyung, Jeon, Bu-Nam, Kim, Mira, Moon, Soojung, Park, Kyung Mi, Park, Hansoo

“…Abstract As a novel immune checkpoint, we previously confirmed that contactin 4 (CNTN4) regulates T cell activity negatively by binding to amyloid precursor…”
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Abstract 2968: Development of anti-APP antibody targeting APP/CNTN4 axis as a novel cancer immunotherapy by Cha, Mi Young, Ha, Youngeun, Jeon, Bu-Nam, Kim, Hyunuk, Kim, Yunyeon, Lee, Jiyeong, Kim, Han-Sol, Jeong, A-Reum, Yu, Hyunkyung, Park, Kyung Mi, Park, Hansoo

“…Abstract Immunotherapeutic treatment has profoundly improved the clinical outcomes in patients with advanced cancers. However, most patients still have not…”
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Abstract 1868: Novel immune checkpoint inhibitor: In vivo and in vitro efficacy of anti-CNTN4 antibody, GENA-104A16 in the models with increased CNTN4 expression by Cha, Mi Young, Yu, Hyunkyung, Jeon, Bu-Nam, Ha, Youngeun, Kim, Hyunuk, Kim, Yunyeon, Chung, Joo-Yeon, Kim, Gihyeon, Park, Changho, Park, Kyung Mi, Park, Hansoo

“…Abstract We previously suggested that contactin 4 (CNTN4) negatively regulates T cell activity through binding with amyloid precursor protein on T cells. In…”
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Micromorphological and chemical aspects of archaeological bamboos under long-term waterlogged condition by Cha, Mi Young, Lee, Kwang Ho, Kim, Yoon Soo

“…Bamboos have been widely used as documentation material in Far Eastern countries even after the wide-spread paper in those countries. A large number of bamboo…”
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Abstract 592: TLT2 expressed on B cells and Bregs suppresses T cell activity, and treatment of the anti-TLT2 antibody, GENA-105S05, induces tumor growth inhibition in a syngeneic mouse model by Cha, Mi Young, Jeon, Bu-Nam, Yang, Hyunsuk, Byun, Seungmin, Jeong, Areum, Chung, Joo-Yeon, Kim, Sanggyun, Park, Kyung Mi, Park, Hansoo

“…Abstract TLT2 (TREML2, Triggering Receptor Expressed on Myeloid cells Like transcript 2) is a single-pass type I membrane protein that contains an…”
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QSAR studies on piperazinylalkylisoxazole analogues selectively acting on dopamine D3 receptor by HQSAR and CoMFA by Cha, Mi Young, Lee, In Young, Cha, Joo Hwan, Choi, Kyung Il, Cho, Yong Seo, Koh, Hun Yeong, Pae, Ae Nim

“…QSAR studies for piperazinylalkylisoxazole analogues were conducted by hologram QSAR (HQSAR) and comparative molecular field analysis (CoMFA) to explain the…”
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Design and synthesis of a piperazinylalkylisoxazole library for subtype selective dopamine receptor ligands by Cha, Mi Young, Choi, Byung Chul, Kang, Kyung Ho, Pae, Ae Nim, Choi, Kung Il, Cho, Yong Seo, Koh, Hun Yeong, Lee, Hee-Yoon, Jung, Daeyoung, Kong, Jae Yang

“…A piperazinylbutylisoxazole libary was designed, synthesized and screened for the binding affinities to dopamine D 2, D 3, and D 4 receptors. Several ligands…”
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Back Cover: Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy (Angew. Chem. Int. Ed. 20/2014) by Koh, Minseob, Park, Jongmin, Koo, Ja Young, Lim, Donghyun, Cha, Mi Young, Jo, Ala, Choi, Jang Hyun, Park, Seung Bum

“…Small-molecule glucose uptake enhancers targeted to myotubes and adipocytes were developed through a phenotypic screening linked with target identification and…”
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Abstract 1760: The antibody-drug conjugate GENA-111 conjugated to auristatin F shows therapeutic potency in BCAM positive epithelial cancer by Yu, Hyunkyung, Bellocq, Nathalie, Ha, Youngeun, Kim, Hyunuk, Kim, Yunyeon, Jeon, Bu-Nam, Marx, Léo, Pantin, Mathilde, Yoo, Hyunjin, Byun, Seungmin, Chung, Joo-Yeon, Cha, Mi Young, Garrouste, Patrick, Lévy, Frédéric

“…Abstract Antibody-drug conjugates (ADCs) are considered as promising cancer treatment modalities that combine the selectivity of antibodies and the cytotoxic…”
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Abstract 2862: Novel immune checkpoint protein CNTN4 and the preclinical efficacy of affinity matured anti-CNTN4 antibody GENA-104A16 by Cha, Mi Young, yu, Hnkyung, Jeon, Bu-Nam, Kim, Hyunuk, Ha, Youngeun, Kim, Yunyeon, Chung, Joo-Yeon, Moon, Soojung, Youn, Hyunseong, Kim, Han-sol, Park, Kyung Mi, Park, Hansoo

“…Abstract The immunotherapeutic treatment has profoundly improved the clinical outcomes in patients with advanced cancers. However, most patients still have not…”
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