Search Results - "Chęcińska, Agnieszka"
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Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells
Published in Cancer cell (04-08-2009)“…Inappropriate drug delivery, secondary toxicities, and persistent chemo- and immunoresistance have traditionally compromised treatment response in melanoma…”
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Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Published in Cell stem cell (02-02-2017)“…Epithelial to mesenchymal transition (EMT) in cancer cells has been associated with metastasis, stemness, and resistance to therapy. Some tumors undergo EMT…”
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The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells
Published in Molecular cancer (17-11-2007)“…Bortezomib is a novel anti-cancer agent which has shown promising activity in non-small lung cancer (NSCLC) patients. However, only a subset of patients…”
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Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells
Published in Journal of proteomics (02-05-2009)“…Apoptosis is a process of cellular suicide executed by caspases. Impaired activation of caspase-9 may contribute to chemoresistance in cancer. Activation of…”
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Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: A small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation
Published in Experimental cell research (01-04-2007)“…X-linked IAP (XIAP) suppresses apoptosis by binding to initiator caspase-9 and effector caspases-3 and -7. Smac/DIABLO that is released from mitochondria…”
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Działalność instytucji otoczenia biznesu w zakresie wspierania rozwoju przedsiębiorstw instrumentami przemysłu spotkań
Published in Ekonomiczne Problemy Turystyki Online (01-06-2018)“…The cooperation between enterprises and the broadly understood business environment institutions (BEIs) is one of the study areas in the field of enterprise…”
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TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells
Published in BMC cancer (23-06-2006)“…Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to…”
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The Expression of TUCAN, an Inhibitor of Apoptosis Protein, in Patients with Advanced Non-small Cell Lung Cancer Treated with Chemotherapy
Published in Anticancer research (01-09-2006)“…Background: TUCAN is a caspase recruitment domain (CARD)-containing protein involved in tumor biology by regulating apoptosis and the NFκB pathway. Inhibition…”
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Wpływ nowych mediów na zachowanie klientów na rynku
Published in Annales Universitatis Mariae Curie-Skłodowska. Sectio H. Oeconomia (2015)“…The aim of the research, the results of which are presented in this paper, was to determine factors responsible for the effective employment of new media in…”
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Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5
Published in Autophagy (02-10-2016)“…Melanoma is a paradigm of aggressive tumors with a complex and heterogeneous genetic background. Still, melanoma cells frequently retain developmental traits…”
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SUPPORTING INNOVATION FOR TOURISM DEVELOPMENT: THE CASE OF LOAN FUND „DEVELOPMENT OF TOURISM IN MALOPOLSKA
Published in Annals of the Polish Association of Agricultural and Agribusiness Economists (10-01-2018)“…The aim of the study is to analyze the determinants and effects of tourism development support from the funds of the loan fund. The objective of the study was…”
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The Influence of New Media on the Customer’s Behavior on the Market
Published in Annales Universitatis Mariae Curie-Skłodowska. Sectio H. Oeconomia (07-07-2015)Get full text
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The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy
Published in Pigment cell and melanoma research (01-12-2011)“…Summary True to their inherent aggressive behavior, melanomas keep impressing the melanoma community with their ability to bypass tumor suppressor mechanisms…”
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E2F1-dependent oncogenic addiction of melanoma cells to MDM2
Published in Oncogene (16-02-2012)“…One of the defining features of aggressive melanomas is their complexity. Hundreds of mutations and an ever increasing list of changes in the transcriptome and…”
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Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460
Published in Molecular cancer therapeutics (01-03-2007)“…Defects in the apoptotic machinery may contribute to chemoresistance of non-small cell lung cancer (NSCLC) cells. We have previously showed a deficiency in…”
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Correspondence re: L. Yang et al., Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide. Cancer Res., 63: 831-837, 2003
Published in Cancer research (Chicago, Ill.) (01-10-2003)Get full text
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