Search Results - "Chênais, Nathalie"
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Somatic cell nuclear transfer in non-enucleated goldfish oocytes: understanding DNA fate during oocyte activation and first cellular division
Published in Scientific reports (28-08-2019)“…Nuclear transfer consists in injecting a somatic nucleus carrying valuable genetic information into a recipient oocyte to sire a diploid offspring which bears…”
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TGFβ inhibition and mesenchymal to epithelial transition initiation by Xenopus egg extract: first steps towards early reprogramming in fish somatic cell
Published in Scientific reports (20-06-2023)“…Xenopus egg extract is a powerful material to modify cultured cells fate and to induce cellular reprogramming in mammals. In this study, the response of…”
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Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish
Published in Molecular biology and evolution (01-10-2020)“…Abstract Chaperone-mediated autophagy (CMA) is a major pathway of lysosomal proteolysis recognized as a key player of the control of numerous cellular…”
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Nuclear import of Xenopus egg extract components into cultured cells for reprogramming purposes: a case study on goldfish fin cells
Published in Scientific reports (27-02-2019)“…Reprogramming of cultured cells using Xenopus egg extract involves controlling four major steps: plasma membrane permeabilization, egg factors import into the…”
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Divergent prion strain evolution driven by PrPC expression level in transgenic mice
Published in Nature communications (23-01-2017)“…Prions induce a fatal neurodegenerative disease in infected host brain based on the refolding and aggregation of the host-encoded prion protein PrP C into PrP…”
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Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy
Published in PLoS pathogens (01-10-2006)“…To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain…”
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Fin cell cryopreservation and fish reconstruction by nuclear transfer stand as promising technologies for preservation of finfish genetic resources
Published in Aquaculture international (01-02-2014)“…Domestication is a long-term process during which wild fish are acclimated to farming conditions and hopefully are reproduced over several generations,…”
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Optimization of somatic cell injection in the perspective of nuclear transfer in goldfish
Published in BMC developmental biology (08-06-2010)“…Nuclear transfer has the potential to become one strategy for fish genetic resources management, by allowing fish reconstruction from cryopreserved somatic…”
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Application of somatic cell cryopreservation for biodiversity conservation
Published in Cryobiology (01-12-2015)Get full text
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Divergent prion strain evolution driven by PrP C expression level in transgenic mice
Published in Nature communications (23-01-2017)“…Prions induce a fatal neurodegenerative disease in infected host brain based on the refolding and aggregation of the host-encoded prion protein PrP into PrP …”
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Stabilization of gene expression and cell morphology after explant recycling during fin explant culture in goldfish
Published in Experimental cell research (01-07-2015)“…The development of fin primary cell cultures for in vitro cellular and physiological studies is hampered by slow cell outgrowth, low proliferation rate, poor…”
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Targeted knock-down of cellular prion protein expression in myelinating Schwann cells does not alter mouse prion pathogenesis
Published in Journal of general virology (01-06-2013)“…In naturally acquired transmissible spongiform encephalopathies, the pathogenic agents or prions spread from the sites of initial peripheral uptake or…”
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Goat SRY induces testis development in XX transgenic mice
Published in FEBS letters (26-06-2006)“…The testis-determining gene SRY is not well-conserved among mammals, particularly between mouse and other mammals, both in terms of protein structure and of…”
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Spatial and temporal down-regulation of transgene expression using the TRSID-silencer in mice: Application to Prnp
Published in FEBS letters (25-06-2008)“…Spatial and temporal control of ovine prion protein ( Prnp) gene expression was achieved in mice using two transgenes: a Prnp minigene with tet-operator…”
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