Search Results - "Chávez‐Riveros, Alejandra"

Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance by Abouelhassan, Yasmeen, Garrison, Aaron T, Yang, Hongfen, Chávez-Riveros, Alejandra, Burch, Gena M, Huigens, Robert W

“…Bacteria utilize multiple mechanisms that enable them to gain or acquire resistance to antibiotic therapies during the treatment of infections. In addition,…”
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EC359: A First-in-Class Small-Molecule Inhibitor for Targeting Oncogenic LIFR Signaling in Triple-Negative Breast Cancer by Viswanadhapalli, Suryavathi, Luo, Yiliao, Sareddy, Gangadhara R, Santhamma, Bindu, Zhou, Mei, Li, Mengxing, Ma, Shihong, Sonavane, Rajni, Pratap, Uday P, Altwegg, Kristin A, Li, Xiaonan, Chang, Annabel, Chávez-Riveros, Alejandra, Dileep, Kalarickal V, Zhang, Kam Y J, Pan, Xinlei, Murali, Ramachandran, Bajda, Marek, Raj, Ganesh V, Brenner, Andrew J, Manthati, Vijaya, Rao, Manjeet K, Tekmal, Rajeshwar R, Nair, Hareesh B, Nickisch, Klaus J, Vadlamudi, Ratna K

“…Leukemia inhibitory factor receptor (LIFR) and its ligand LIF play a critical role in cancer progression, metastasis, stem cell maintenance, and therapy…”
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A Two‐Step Multicomponent Synthetic Approach and Anti‐inflammatory Evaluation of N‐Substituted 2‐Oxopyrazines by Hernández‐Vázquez, Eduardo, Chávez‐Riveros, Alejandra, Nieto‐Camacho, Antonio, Miranda, Luis D.

“…Inflammation is widely reported as a main factor for the development of chronic diseases such as cancer, diabetes, and even metabolic syndrome. Thus, the…”
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Cytotoxic Activity and Structure–Activity Relationship of Triazole‐Containing Bis(Aryl Ether) Macrocycles by Hernández‐Vázquez, Eduardo, Chávez‐Riveros, Alejandra, Romo‐Pérez, Adriana, Ramírez‐Apán, María Teresa, Chávez‐Blanco, Alma D., Morales‐Bárcenas, Rocío, Dueñas‐González, Alfonso, Miranda, Luis D.

“…Cancer continues to be a worldwide health problem. Certain macrocyclic molecules have become attractive therapeutic alternatives for this disease because of…”
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Synthesis and Identification of Pregnenolone Derivatives as Inhibitors of Isozymes of 5α-Reductase by Chávez-Riveros, Alejandra, Bratoeff, Eugene, Heuze, Yvonne, Soriano, Juan, Moreno, Isabel, Sánchez-Márquez, Araceli, Cabeza, Marisa

“…Hyperplasia of the prostate gland and prostate cancer have been associated with high levels of serum 5α‐dihydrotestosterone. This steroid is formed from…”
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Expanding the structure-activity relationship of cytotoxic diphenyl macrocycles by Chávez-Riveros, Alejandra, Ramírez-Trinidad, Ángel, Hernández-Vázquez, Eduardo, Miranda, Luis D.

“…[Display omitted] Twenty-four biaryl tetrapeptide macrocycles were synthesized as an extension of our previous work. Two groups of compounds were constructed…”
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Multicomponent synthesis and preliminary anti-inflammatory activity of lipophilic diphenylamines by Chávez-Riveros, Alejandra, Hernández-Vázquez, Eduardo, Ramírez-Trinidad, Ángel, Nieto-Camacho, Antonio, Miranda, Luis D.

“…[Display omitted] Non-Steroidal Anti-inflammatory Drugs (NSAIDs) are some of the most prescribed medications for pain but the incidence of adverse effects…”
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Synthesis and cytotoxic effect of pregnenolone derivatives with one or two α,β-unsaturated carbonyls and an ester moiety at C-21 or C-3 by Chávez-Riveros, Alejandra, Cruz Noriega, Abigail, Ramírez Apan, María Teresa, Miranda, Luis D., Bratoeff, Eugene

“…[Display omitted] •Synthesis of four series of pregnenolone derivatives.•Comparison study between the cytotoxicity of steroids with an ester group at C-21 or…”
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Diversity-oriented synthesis and cytotoxic activity evaluation of biaryl-containing macrocycles by Pérez-Labrada, Karell, Cruz-Mendoza, Marco A, Chávez-Riveros, Alejandra, Hernández-Vázquez, Eduardo, Torroba, Tomás, Miranda, Luis D

“…Synthesis of biaryl-containing macrocycles has been carried out through a four-step approach comprising two Ugi four component reactions and a Suzuki-Miyaura…”
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Synthesis and cytotoxic effect on cancer cell lines and macrophages of novel progesterone derivatives having an ester or a carbamate function at C-3 and C-17 by Chávez-Riveros, Alejandra, Garrido, Mariana, Ramírez Apan, María Teresa, Zambrano, Armando, Díaz, Mario, Bratoeff, Eugene

“…In this study we report the cytotoxic effect on human cancer cells of two series of novel progesterone derivatives; the first containing an aromatic ester…”
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Effect of two antiandrogens as protectors of prostate and brain in a Huntington's animal model by Guzman, David Calderon, Bratoeff, Eugene, Riveros, Alejandra Chavez, Brizuela, Norma Osnaya, Mejia, Gerardo Barragan, Garcia, Ernestina Hernandez, Olguin, Hugo Juarez, Cruz, Edna Garcia

“…The purpose of this work is to know the effect of flutamide and a novel synthetic steroid 3β-p-Iodobenzoyloxypregnan-4,16- diene-6,20-dione (IBP) on the levels…”
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Abstract 4716: Therapeutic utility of EC359 for targeting oncogenic LIFR signaling in triple negative breast cancer by Viswanadhapalli, Suryavathi, Li, Mengxing, Luo, Yiliao, Sareddy, Gangadhara R, Santhamma, Bindu, Zhou, Mei, Ma, Shihong, Sonavane, Rajni, Pratap, Uday P., Altwegg, Kristin A., Chang, Annabel, Chávez-Riveros, Alejandra, Dileep, Kalarickal V., Zhang, Kam Y., Bajda, Marek, Raj, Ganesh V., Brenner, Andrew, Manthati, Vijaya, Rao, Manjeet, Tekmal, Rajeshwar R., Nair, Hareesh B., Nickisch, Klaus J., Vadlamudi, Ratna K.

“…Abstract Background: Leukemia inhibitory factor receptor (LIFR) and its ligand LIF play a major critical role in cancer progression, metastasis, stem cell…”
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A new approach towards the synthesis of drospirenone and steroidal spirolactones by Santhamma, Bindu, Acosta, Kirk, Chavez-Riveros, Alejandra, Nickisch, Klaus

“…[Display omitted] •A new methodology for the synthesis of steroidal 17-spirolactones is described.•The method use lithium acetylide of ethyl propiolate as the…”
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Utilizing cell line-derived organoids to evaluate the efficacy of a novel LIFR-inhibitor, EC359 in targeting pancreatic tumor stroma by Hall, Bradley R, Cannon, Andrew, Thompson, Christopher, Santhamma, Bindu, Chavez-Riveros, Alejandra, Bhatia, Rakesh, Nair, Hareesh B, Nickisch, Klaus, Batra, Surinder K, Kumar, Sushil

“…Survival of pancreatic cancer (PC) patient is poor due to lack of effective treatment modalities, which is partly due to the presence of dense desmoplasia that…”
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Synthesis and Identification of Pregnenolone Derivatives as Inhibitors of Isozymes of 5[alpha]-Reductase by Chavez-Riveros, Alejandra, Bratoeff, Eugene, Heuze, Yvonne, Soriano, Juan, Moreno, Isabel, Sanchez-Marquez, Araceli, Cabeza, Marisa

“…Hyperplasia of the prostate gland and prostate cancer have been associated with high levels of serum 5[alpha]-dihydrotestosterone. This steroid is formed from…”
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