Search Results - "Chávez, Jorge L"

Electrokinetic Preconcentration and Detection of Neuropeptides at Patterned Graphene-Modified Electrodes in a Nanochannel by Sanghavi, Bankim J., Varhue, Walter, Chávez, Jorge L., Chou, Chia-Fu, Swami, Nathan S.

“…Neuropeptides are vital to the transmission and modulation of neurological signals, with Neuropeptide Y (NPY) and Orexin A (OXA) offering diagnostic…”
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Aptamer-functionalized nanoparticles for surface immobilization-free electrochemical detection of cortisol in a microfluidic device by Sanghavi, Bankim J., Moore, John A., Chávez, Jorge L., Hagen, Joshua A., Kelley-Loughnane, Nancy, Chou, Chia-Fu, Swami, Nathan S.

“…Monitoring the periodic diurnal variations in cortisol from small volume samples of serum or saliva is of great interest, due to the regulatory role of…”
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Incoherent merger network for robust ratiometric gene expression response by Kwon, Ukjin, Huang, Hsin-Ho, Chávez, Jorge L, Beabout, Kathryn, Harbaugh, Svetlana, Del Vecchio, Domitilla

“…Abstract A ratiometric response gives an output that is proportional to the ratio between the magnitudes of two inputs. Ratio computation has been observed in…”
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Physicochemical Trapping of Neurotransmitters in Polymer-Mediated Gold Nanoparticle Aggregates for Surface-Enhanced Raman Spectroscopy by Vander Ende, Emma, Bourgeois, Marc R, Henry, Anne-Isabelle, Chávez, Jorge L, Krabacher, Rachel, Schatz, George C, Van Duyne, Richard P

“…Because of the sharp distance dependence of surface-enhanced Raman spectroscopy (SERS), analyte molecules that do not exhibit strong affinity for Au/Ag often…”
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Colorimetric detection with aptamer-gold nanoparticle conjugates coupled to an android-based color analysis application for use in the field by Smith, Joshua E., Griffin, Daniel K., Leny, Juliann K., Hagen, Joshua A., Chávez, Jorge L., Kelley-Loughnane, Nancy

“…The feasibility of using aptamer-gold nanoparticle conjugates (Apt-AuNPs) to design colorimetric assays for in the field detection of small molecules was…”
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Programming Fluorogenic DNA Probes for Rapid Detection of Steroids by Ebrahimi, Sasha B., Samanta, Devleena, Partridge, Benjamin E., Kusmierz, Caroline D., Cheng, Ho Fung, Grigorescu, Arabela A., Chávez, Jorge L., Mirau, Peter A., Mirkin, Chad A.

“…The ability of aptamers to recognize a variety of different molecules has fueled their emergence as recognition agents to probe complex media and cells. Many…”
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Quantification of Interlaboratory Cell-Free Protein Synthesis Variability by Cole, Stephanie D, Beabout, Kathryn, Turner, Kendrick B, Smith, Zachary K, Funk, Vanessa L, Harbaugh, Svetlana V, Liem, Alvin T, Roth, Pierce A, Geier, Brian A, Emanuel, Peter A, Walper, Scott A, Chávez, Jorge L, Lux, Matthew W

“…Cell-free protein synthesis (CFPS) platforms, once primarily a research tool to produce difficult to express proteins, are increasingly being pursued by the…”
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Optimization of Heavy Metal Sensors Based on Transcription Factors and Cell-Free Expression Systems by Beabout, Kathryn, Bernhards, Casey B, Thakur, Meghna, Turner, Kendrick B, Cole, Stephanie D, Walper, Scott A, Chávez, Jorge L, Lux, Matthew W

“…Many bacterial mechanisms for highly specific and sensitive detection of heavy metals and other hazards have been reengineered to serve as sensors. In some…”
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Highly multiplexed design of an allosteric transcription factor to sense new ligands by Nishikawa, Kyle K., Chen, Jackie, Acheson, Justin F., Harbaugh, Svetlana V., Huss, Phil, Frenkel, Max, Novy, Nathan, Sieren, Hailey R., Lodewyk, Ella C., Lee, Daniel H., Chávez, Jorge L., Fox, Brian G., Raman, Srivatsan

“…Allosteric transcription factors (aTF) regulate gene expression through conformational changes induced by small molecule binding. Although widely used as…”
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Engineering a Synthetic Dopamine-Responsive Riboswitch for In Vitro Biosensing by Harbaugh, Svetlana V., Silverman, Adam D., Chushak, Yaroslav G., Zimlich, Kathryn, Wolfe, Monica, Thavarajah, Walter, Jewett, Michael C., Lucks, Julius B., Chávez, Jorge L.

“…The detection of chemicals using natural allosteric transcription factors is a powerful strategy for point-of-use molecular sensing, particularly using…”
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Rational Approach to Optimizing Conformation-Switching Aptamers for Biosensing Applications by Wolfe, Monica, Cramer, Alyssa, Webb, Sean, Goorskey, Eva, Chushak, Yaroslav, Mirau, Peter, Arroyo-Currás, Netzahualcóyotl, Chávez, Jorge L.

“…The utilization of structure-switching aptamers (SSAs) has enabled the development of novel sensing platforms for the sensitive and continuous detection of…”
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Single-molecule DNA origami aptasensors for real-time biomarker detection by Cervantes-Salguero, Keitel, Freeley, Mark, Chávez, Jorge L, Palma, Matteo

“…Here we report the use of DNA nanostructures as platforms to monitor the inherent conformational changes of aptamers upon analyte binding, with single-molecule…”
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Detection of Bile Acids in Complex Matrices Using a Transcription Factor-Based Biosensor by Beabout, Kathryn, Ehrenworth Breedon, Amy M., Blum, Steven M., Miklos, Aleksandr E., Lux, Matthew W., Chávez, Jorge L., Goodson, Michael S.

“…Bile acids play an important role in digestion and human health, are found throughout the gastrointestinal tract, and are excreted in feces. Therefore, bile…”
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Cross-Reactive Plasmonic Aptasensors for Controlled Substance Identification by Yoho, Joshua N, Geier, Brian, Grigsby, Claude C, Hagen, Joshua A, Chávez, Jorge L, Kelley-Loughnane, Nancy

“…In this work, we developed an assay to determine if an arbitrary white powder is a controlled substance, given the plasmonic response of aptamer-gold…”
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Content and evolution of potential furfural compounds in commercial milk-based infant formula powder after opening the packet by Chávez-Servín, Jorge L., de la Torre Carbot, Karina, García-Gasca, Teresa, Castellote, Ana I., López-Sabater, M. Carmen

“…•We analysed potential furfural compounds in powdered infant formula brands.•We traced the evolution after the packets had been opened from 0 to 70days.•Slight…”
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Biofunctionalized zinc oxide field effect transistors for selective sensing of riboflavin with current modulation by Hagen, Joshua A, Kim, Sang N, Bayraktaroglu, Burhan, Leedy, Kevin, Chávez, Jorge L, Kelley-Loughnane, Nancy, Naik, Rajesh R, Stone, Morley O

“…Zinc oxide field effect transistors (ZnO-FET), covalently functionalized with single stranded DNA aptamers, provide a highly selective platform for label-free…”
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Rational Design of Peptide Biorecognition Elements on Carbon Nanotubes for Sensing Volatile Organic Compounds by Sim, Daniel, Kuang, Zhifeng, Sant'Anna, Gustavo, Krabacher, Rachel M., Brothers, Michael C., Chávez, Jorge L., Martin, Jennifer A., Islam, Ahmad E., Maruyama, Benji, Naik, Rajesh R., Bedford, Nicholas M., Kim, Steve S.

“…Carbon nanotube (CNT) chemiresistors have emerged as miniaturized platforms for wearable volatile organic compound (VOC) sensors. As a promising biorecognition…”
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Nanoparticle-Mediated Signaling for Aptamer-Based Multiplexed Detection of Cortisol and Neuropeptide Y in Serum by Sardesai, Naimesh, Liu, Yi, Shia, Regina, Mirau, Peter, Chávez, Jorge L., Swami, Nathan S.

“…Multiplexed profiling of the expression of neurochemical biomarkers of stress, for periodic assessment to enable augmentation of human performance, requires…”
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Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers by Hagen, Joshua A., Chávez, Jorge L., Chushak, Yaroslav, Martin, Jennifer A., Kelley-Loughnane, Nancy

“…Immobilization of nucleic acid aptamer recognition elements selected free in solution onto the surface of biosensor platforms has proven challenging. This…”
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Core−Shell Nanoparticles:  Characterization and Study of Their Use for the Encapsulation of Hydrophobic Fluorescent Dyes by Chávez, Jorge L, Wong, Jeffrey L, Duran, Randolph S

“…Core−shell nanocapsules intended to be used as drug scavengers were prepared using a surfactant mixture containing octadecyltrimethoxysilane (OTMS) as a…”
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