Search Results - "Cezar de Cerqueira Leite, Luciana"

The Challenges Imposed by Dengue, Zika, and Chikungunya to Brazil by Zanotto, Paolo Marinho de Andrade, Leite, Luciana Cezar de Cerqueira

“…Brazil has a well-established immunization program in which vaccines are provided through the Public Health System free of charge to the whole population,…”
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Current status and perspectives on protein-based pneumococcal vaccines by Darrieux, Michelle, Goulart, Cibelly, Briles, David, Leite, Luciana Cezar de Cerqueira

“…Despite the efforts to expand the availability of conjugate vaccines, pneumococcal diseases still pose an enormous burden worldwide. Therefore, several…”
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CRISPR/Cas9 Approach to Generate an Auxotrophic BCG Strain for Unmarked Expression of LTAK63 Adjuvant: A Tuberculosis Vaccine Candidate by Moraes, Luana, Trentini, Monalisa Martins, Fousteris, Dimitrios, Eto, Silas Fernandes, Chudzinski-Tavassi, Ana Marisa, Leite, Luciana Cezar de Cerqueira, Kanno, Alex Issamu

“…Tuberculosis is one of the deadliest infectious diseases and a huge healthcare burden in many countries. New vaccines, including recombinant BCG-based…”
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Screening the Schistosoma mansoni transcriptome for genes differentially expressed in the schistosomulum stage in search for vaccine candidates by Farias, Leonardo P, Tararam, Cibele A, Miyasato, Patricia A, Nishiyama, Milton Y. Jr, Oliveira, Katia C, Kawano, Toshie, Verjovski-Almeida, Sergio, Leite, Luciana Cezar de Cerqueira

“…Schistosomiasis affects more than 200 million people worldwide; another 600 million are at risk of infection. The schistosomulum stage is believed to be the…”
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Recombinant BCG expressing the LTAK63 adjuvant induces increased early and long-term immune responses against Mycobacteria by Carvalho Dos Santos, Carina, Rodriguez, Dunia, Kanno Issamu, Alex, Cezar De Cerqueira Leite, Luciana, Pereira Nascimento, Ivan

“…The development of more effective vaccines against Mycobacterium tuberculosis has become a world priority. Previously, we have shown that a recombinant BCG…”
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Systems Biology Analysis of the Radiation-Attenuated Schistosome Vaccine Reveals a Role for Growth Factors in Protection and Hemostasis Inhibition in Parasite Survival by Farias, Leonardo Paiva, Vitoriano-Souza, Juliana, Cardozo, Lucas Esteves, Gama, Leonardo Dos Reis, Singh, Youvika, Miyasato, Patrícia Aoki, Almeida, Giulliana Tessarin, Rodriguez, Dunia, Barbosa, Mayra Mara Ferrari, Fernandes, Rafaela Sachetto, Barbosa, Tereza Cristina, Neto, Almiro Pires da Silva, Nakano, Eliana, Ho, Paulo Lee, Verjovski-Almeida, Sergio, Nakaya, Helder Imoto, Wilson, Robert Alan, Leite, Luciana Cezar de Cerqueira

“…In spite of several decades of research, an effective vaccine against schistosomiasis remains elusive. The radiation-attenuated (RA) cercarial vaccine is still…”
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Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology by Kanno, Alex Issamu, Leite, Luciana Cezar de Cerqueira, Pereira, Lennon Ramos, de Jesus, Mônica Josiane Rodrigues, Andreata-Santos, Robert, Alves, Rúbens Prince dos Santos, Durigon, Edison Luiz, Ferreira, Luís Carlos de Souza, Gonçalves, Viviane Maimoni

“…Diagnosing Zika virus (ZIKV) infections has been challenging due to the cross-reactivity of induced antibodies with other flavivirus. The concomitant…”
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Schistosoma mansoni Annexin 2: Molecular characterization and immunolocalization by Tararam, Cibele Aparecida, Farias, Leonardo Paiva, Wilson, R. Alan, Leite, Luciana Cezar de Cerqueira

“…We here describe the cloning and characterization of the Schistosoma mansoni Annexin 2, previously identified in the tegument by proteomic studies, and as an…”
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Recombinant BCG expressing the LTAK63 adjuvant increased memory T cells and induced long-lasting protection against Mycobacterium tuberculosis challenge in mice by Marques-Neto, Lázaro Moreira, Trentini, Monalisa Martins, Kanno, Alex Issamu, Rodriguez, Dunia, Leite, Luciana Cezar de Cerqueira

“…Vaccine-induced protection against is usually ascribed to the induction of Th1, Th17, and CD8 T cells. However, protective immune responses should also involve…”
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Recombinant BCG expressing the LTAK63 adjuvant improves a short-term chemotherapy schedule in the control of tuberculosis in mice by Trentini, Monalisa Martins, Kanno, Alex Issamu, Rodriguez, Dunia, Marques-Neto, Lazaro Moreira, Eto, Silas Fernandes, Chudzinki-Tavassi, Ana Marisa, Leite, Luciana Cezar de Cerqueira

“…Tuberculosis (TB) is one of the deadliest infectious diseases around the world. Prevention is based on the prophylactic use of BCG vaccine, effective in…”
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Robust Immune Response and Protection against Lethal Pneumococcal Challenge with a Recombinant BCG-PspA-PdT Prime/Boost Scheme Administered to Neonatal Mice by Trentini, Monalisa Martins, Rodriguez, Dunia, Kanno, Alex Issamu, Goulart, Cibelly, Darrieux, Michelle, de Cerqueira Leite, Luciana Cezar

“…Pneumococcal diseases are an important public health problem, with high mortality rates in young children. Although conjugated pneumococcal vaccines offer high…”
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Peptide linker increased the stability of pneumococcal fusion protein vaccine candidate by Zane, Luciano, Kraschowetz, Stefanie, Trentini, Monalisa Martins, Alves, Vitor Dos Santos, Araujo, Sergio Carneiro, Goulart, Cibelly, Leite, Luciana Cezar de Cerqueira, Gonçalves, Viviane Maimoni

“…is a bacterial pathogen exclusive to humans, responsible for respiratory and systemic diseases. Pneumococcal protein vaccines have been proposed as…”
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Co-expression gene module analysis in response to attenuated cercaria vaccine reveals a critical role for NK cells in protection against Schistosoma mansoni by Neto, Almiro Pires da Silva, Vitoriano-Souza, Juliana, Khouri, Mariana Ivo, Favaro, Regiane Degan, Wilson, Robert Alan, Leite, Luciana Cezar de Cerqueira, Ramos, Pablo Ivan Pereira, Farias, Leonardo Paiva

“…Despite decades of research, an effective schistosomiasis vaccine remains elusive. The radiation-attenuated (RA) cercarial vaccine remains the best model for…”
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Vitamins as influenza vaccine adjuvant components by Quintilio, Wagner, de Freitas, Fábio Alessandro, Rodriguez, Dunia, Kubrusly, Flavia Saldanha, Yourtov, Dimitri, Miyaki, Cosue, de Cerqueira Leite, Luciana Cezar, Raw, Isaias

“…A number of adjuvant formulations were assayed in mice immunized with 3.75 µg of A/California/7/2009 (H1N1) pdm09 influenza vaccine with vitamins A, D and/or E…”
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Purification of catalase from human placenta by Maimoni Gonçalves, Viviane, Cezar de Cerqueira Leite, Luciana, Raw, Isaias, Cabrera-Crespo, Joaquin

“…The therapeutic use of an antioxidant complex containing superoxide dismutase and catalase has been proposed for the treatment of several diseases in which…”
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