Search Results - "Ceusters, Justine"

Equine Muscle Derived Mesenchymal Stem Cells Loaded with Water-Soluble Curcumin: Modulation of Neutrophil Activation and Enhanced Protection against Intracellular Oxidative Attack by Franck, Thierry, Ceusters, Justine, Graide, Hélène, Niesten, Ariane, Duysens, Julien, Mickalad, Ange Mouithys, Serteyn, Didier

“…We investigated the antioxidant potential of equine mesenchymal stem cells derived from muscle microbiopsies (mdMSCs), loaded by a water-soluble curcumin…”
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Optimization of the Amplification of Equine Muscle-Derived Mesenchymal Stromal Cells in a Hollow-Fiber Bioreactor by Duysens, Julien, Graide, Hélène, Niesten, Ariane, Mouithys-Mickalad, Ange, Ceusters, Justine, Serteyn, Didier

“…The main causes of mortality in horses are the gastrointestinal pathologies associated with septic shock. Stem cells have shown, through systemic injection, a…”
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Muscle Derived Mesenchymal Stem Cells Inhibit the Activity of the Free and the Neutrophil Extracellular Trap (NET)-Bond Myeloperoxidase by Franck, Thierry, Ceusters, Justine, Graide, Hélène, Mouithys-Mickalad, Ange, Serteyn, Didier

“…Mesenchymal stem cells (MSCs) are known to migrate to tissue injury sites to participate in immune modulation, tissue remodelling and wound healing, reducing…”
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Curcumin and resveratrol act by different ways on NADPH oxidase activity and reactive oxygen species produced by equine neutrophils by Derochette, Sandrine, Franck, Thierry, Mouithys-Mickalad, Ange, Ceusters, Justine, Deby-Dupont, Ginette, Lejeune, Jean-Philippe, Neven, Philippe, Serteyn, Didier

“…•A cell-free assay was optimized and validated to measure equine Nox2 activity.•The curcumin and resveratrol effects were studied on equine Nox2 by 2…”
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Revealing the Therapeutic Potential of Muscle-Derived Mesenchymal Stem/Stromal Cells: An In Vitro Model for Equine Laminitis Based on Activated Neutrophils, Anoxia-Reoxygenation, and Myeloperoxidase by Serteyn, Didier, Storms, Nazaré, Mouithys-Mickalad, Ange, Sandersen, Charlotte, Niesten, Ariane, Duysens, Julien, Graide, Hélène, Ceusters, Justine, Franck, Thierry

“…Laminitis in horses is a crippling condition marked by the deterioration of the dermal-epidermal interface, leading to intense lameness and discomfort, often…”
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Free Radical Inhibition Using a Water-Soluble Curcumin Complex, NDS27: Mechanism Study Using EPR, Chemiluminescence, and Docking by Mouithys-Mickalad, Ange, Etsè, Koffi Senam, Franck, Thierry, Ceusters, Justine, Niesten, Ariane, Graide, Hélène, Deby-Dupont, Ginette, Sandersen, Charlotte, Serteyn, Didier

“…There is a growing interest in the use of natural compounds to tackle inflammatory diseases and cancers. However, most of them face the bioavailability and…”
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Effects of Juglone on Neutrophil Degranulation and Myeloperoxidase Activity Related to Equine Laminitis by Mouithys-Mickalad, Ange, Storms, Nazaré, Franck, Thierry, Ceusters, Justine, de la Rebière de Pouyade, Geoffroy, Deby-Dupont, Ginette, Serteyn, Didier

“…Experimental laminitis, characterized by a failure of the dermal–epidermal interface of the foot, can be induced in horses by the oral administration of a…”
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Effect of myeloperoxidase and anoxia/reoxygenation on mitochondrial respiratory function of cultured primary equine skeletal myoblasts by Ceusters, Justine D, Mouithys-Mickalad, Ange A, Franck, Thierry J, Derochette, Sandrine, Vanderplasschen, Alain, Deby-Dupont, Ginette P, Serteyn, Didier A

“…Horses are particularly sensitive to excessive inflammatory reaction where myeloperoxidase, a marker of inflammation, may contribute to mitochondrial…”
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An in vitro whole blood model to test the effects of different stimuli conditions on the release of myeloperoxidase and elastase by equine neutrophils by Ceusters, Justine D., Serteyn, Didier A., Minguet, Grégory, de la Rebière de Pouyade, Geoffroy, Romainville, Jennifer, Deby-Dupont, Ginette P., Mouithys-Mickalad, Ange A., Franck, Thierry J.

“…Horses are particularly sensitive and exposed to excessive inflammatory responses evolving toward an important stimulation of polymorphonuclear neutrophils…”
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Assessment of reactive oxygen species production in cultured equine skeletal myoblasts in response to conditions of anoxia followed by reoxygenation with or without exposure to peroxidases by Ceusters, Justine D, Mouithys-Mickalad, Ange A, Pouyade, Geoffroy de la Rebière de, Franck, Thierry J, Votion, Dominique M, Deby-Dupont, Ginette P, Serteyn, Didier A

“…Objective: To culture equine myoblasts from muscle microbiopsy specimens, examine myoblast production of reactive oxygen species (ROS) in conditions of anoxia…”
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Effect of different kinds of anoxia/reoxygenation on the mitochondrial function and the free radicals production of cultured primary equine skeletal myoblasts by Ceusters, Justine D., Mouithys-Mickalad, Ange A., Franck, Thierry J., Deby-Dupont, Ginette P., Derochette, Sandrine, Serteyn, Didier A.

“…Horses are outstanding athletes, performing in many different disciplines involving different kinds of efforts and metabolic responses. Depending on exercise…”
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NDS27 combines the effect of curcumin lysinate and hydroxypropyl-β-cyclodextrin to inhibit equine PKCδ and NADPH oxidase involved in the oxidative burst of neutrophils by Derochette, Sandrine, Mouithys-Mickalad, Ange, Franck, Thierry, Collienne, Simon, Ceusters, Justine, Deby-Dupont, Ginette, Neven, Philippe, Serteyn, Didier

“…•The antioxidant effects of curcumin lysinate complexed with two cyclodextrins were compared.•NDS27 is complexed with hydroxypropyl-β- and NDS28 with…”
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Subconjunctival autologous muscle‐derived mesenchymal stem cell therapy: A novel, minimally invasive approach for treating equine immune‐mediated keratitis by Narinx, Florine, Sauvage, Aurélie, Ceusters, Justine, Grulke, Sigrid, Serteyn, Didier, Monclin, Sébastien

“…Objective To establish the safety of subconjunctival injections of autologous muscle‐derived mesenchymal stem cells (mdMSCs) in healthy horses and to evaluate…”
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Neutrophil extracellular traps and active myeloperoxidase concentrate in lamellar tissue of equids with naturally occurring laminitis by Storms, Nazaré, de la Rebière, Geoffroy, Franck, Thierry, Mouithys Mickalad, Ange, Sandersen, Charlotte, Ceusters, Justine, Serteyn, Didier

“…Laminitis is a pathology of the equine digit ultimately leading to a failure of the dermo-epidermal interface. Neutrophil activation is recognized as a major…”
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Priming of mesenchymal stem cells with a hydrosoluble form of curcumin allows keeping their mesenchymal properties for cell‐based therapy development by Colin, Margaux, Dechêne, Lola, Ceusters, Justine, Niesten, Ariane, Demazy, Catherine, Lagneaux, Laurence, Zouaoui Boudjeltia, Karim, Franck, Thierry, Van Antwerpen, Pierre, Renard, Patricia, Mathieu, Véronique, Serteyn, Didier

“…Mesenchymal stem cells are increasingly studied for their use as drug‐carrier in addition to their intrinsic potential for regenerative medicine. They could be…”
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Modulation of mitochondrial respiration rate and calcium-induced swelling by new cromakalim analogues by Mouithys-Mickalad, Ange, Ceusters, Justine, Charif, Mounia, El Moualij, Benaïssa, Schoumacher, Mathieu, Plyte, Simon, Franck, Thierry, Bettendorff, Lucien, Pirotte, Bernard, Serteyn, Didier, de Tullio, Pascal

“…A cellular model of cardiomyocytes (H9c2 cell line) and mitochondria isolated from mouse liver were used to understand the drug action of BPDZ490 and BPDZ711,…”
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EquiNox2: A new method to measure NADPH oxidase activity and to study effect of inhibitors and their interactions with the enzyme by Derochette, Sandrine, Serteyn, Didier, Mouithys-Mickalad, Ange, Ceusters, Justine, Deby-Dupont, Ginette, Neven, Philippe, Franck, Thierry

“…Excessive neutrophil stimulation and reactive oxygen species (ROS) production are involved in numerous human or horse pathologies. The modulation of the…”
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Nerve Stimulator-guided Injection of Autologous Stem Cells Near the Equine Left Recurrent Laryngeal Nerve by Sandersen, Charlotte, Ceusters, Justine, Fourez, Alexia, Tosi, Irene, Graide, Helene, Lejeune, Jean-Philippe, Serteyn, Didier

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From skeletal muscle to stem cells: an innovative and minimally-invasive process for multiple species by Ceusters, J., Lejeune, J.-Ph, Sandersen, C., Niesten, A., Lagneaux, L., Serteyn, D.

“…Bone marrow and adipose tissue represent the two most commonly exploited sources of adult mesenchymal stem cells for musculoskeletal applications…”
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Nerve Stimulator-guided Injection of Autologous Stem Cells Near the Equine Left Recurrent Laryngeal Nerve by Sandersen, Charlotte, Ceusters, Justine, Fourez, Alexia, Tosi, Irene, Graide, Helene, Lejeune, Jean-Philippe, Serteyn, Didier

“…Recurrent laryngeal neuropathy (RLN) commonly affects horses and is characterized by abnormal respiratory sounds and exercise intolerance. The recurrent…”
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