Search Results - "Cesca, Fabrizia"

Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment by Fadeel, Bengt, Bussy, Cyrill, Merino, Sonia, Vázquez, Ester, Flahaut, Emmanuel, Mouchet, Florence, Evariste, Lauris, Gauthier, Laury, Koivisto, Antti J., Vogel, Ulla, Martín, Cristina, Delogu, Lucia G., Buerki-Thurnherr, Tina, Wick, Peter, Beloin-Saint-Pierre, Didier, Hischier, Roland, Pelin, Marco, Candotto Carniel, Fabio, Tretiach, Mauro, Cesca, Fabrizia, Benfenati, Fabio, Scaini, Denis, Ballerini, Laura, Kostarelos, Kostas, Prato, Maurizio, Bianco, Alberto

“…Graphene and its derivatives are heralded as “miracle” materials with manifold applications in different sectors of society from electronics to energy storage…”
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Synapsin I is an oligomannose-carrying glycoprotein, acts as an oligomannose-binding lectin, and promotes neurite outgrowth and neuronal survival when released via glia-derived exosomes by Wang, Shiwei, Cesca, Fabrizia, Loers, Gabriele, Schweizer, Michaela, Buck, Friedrich, Benfenati, Fabio, Schachner, Melitta, Kleene, Ralf

“…Oligomannosidic glycans play important roles in nervous system development and function. By performing a phage display screening with oligomannose-specific…”
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Kidins220/ARMS controls astrocyte calcium signaling and neuron–astrocyte communication by Jaudon, Fanny, Chiacchiaretta, Martina, Albini, Martina, Ferroni, Stefano, Benfenati, Fabio, Cesca, Fabrizia

“…Through their ability to modulate synaptic transmission, glial cells are key regulators of neuronal circuit formation and activity. Kidins220/ARMS (kinase-D…”
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Interfacing Graphene-Based Materials With Neural Cells by Bramini, Mattia, Alberini, Giulio, Colombo, Elisabetta, Chiacchiaretta, Martina, DiFrancesco, Mattia L, Maya-Vetencourt, José F, Maragliano, Luca, Benfenati, Fabio, Cesca, Fabrizia

“…The scientific community has witnessed an exponential increase in the applications of graphene and graphene-based materials in a wide range of fields, from…”
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Conditional knockout of REST/NRSF in excitatory neurons reduces seizure susceptibility to chemical kindling by Natali, Giulia, Michetti, Caterina, Krawczun-Rygmaczewska, Alicja, Floss, Thomas, Cesca, Fabrizia, Benfenati, Fabio

“…The repressor element-1 silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is an epigenetic master regulator that plays a crucial…”
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Alterations in KIDINS220/ARMS Expression Impact Sensory Processing and Social Behavior in Adult Mice by Albini, Martina, Almacellas-Barbanoj, Amanda, Krawczun-Rygmaczewska, Alicja, Ciano, Lorenzo, Benfenati, Fabio, Michetti, Caterina, Cesca, Fabrizia

“…Kinase D-interacting substrate of 220 kDa (Kidins220) is a transmembrane protein that participates in neural cell survival, maturation, and plasticity…”
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A pH-sensitive closed-loop nanomachine to control hyperexcitability at the single neuron level by Merolla, Assunta, Michetti, Caterina, Moschetta, Matteo, Vacca, Francesca, Ciano, Lorenzo, Emionite, Laura, Astigiano, Simonetta, Romei, Alessandra, Horenkamp, Simone, Berglund, Ken, Gross, Robert E., Cesca, Fabrizia, Colombo, Elisabetta, Benfenati, Fabio

“…Epilepsy affects 1% of the general population and 30% of patients are resistant to antiepileptic drugs. Although optogenetics is an efficient antiepileptic…”
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Specificity Protein 1 (Sp1)-dependent Activation of the Synapsin I Gene (SYN1) Is Modulated by RE1-silencing Transcription Factor (REST) and 5′-Cytosine-Phosphoguanine (CpG) Methylation by Paonessa, Francesco, Latifi, Shahrzad, Scarongella, Helena, Cesca, Fabrizia, Benfenati, Fabio

“…The development and function of the nervous system are directly dependent on a well defined pattern of gene expression. Indeed, perturbation of transcriptional…”
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Neuronal hyperactivity causes Na + /H + exchanger-induced extracellular acidification at active synapses by Chiacchiaretta, Martina, Latifi, Shahrzad, Bramini, Mattia, Fadda, Manuela, Fassio, Anna, Benfenati, Fabio, Cesca, Fabrizia

“…Extracellular pH impacts on neuronal activity, which is in turn an important determinant of extracellular H concentration. The aim of this study was to…”
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Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF by Buffolo, Federica, Petrosino, Valentina, Albini, Martina, Moschetta, Matteo, Carlini, Federico, Floss, Thomas, Kerlero de Rosbo, Nicole, Cesca, Fabrizia, Rocchi, Anna, Uccelli, Antonio, Benfenati, Fabio

“…Neuroinflammation is associated with synapse dysfunction and cognitive decline in patients and animal models. One candidate for translating the inflammatory…”
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Mild Inactivation of RE-1 Silencing Transcription Factor (REST) Reduces Susceptibility to Kainic Acid-Induced Seizures by Carminati, Emanuele, Buffolo, Federica, Rocchi, Anna, Michetti, Caterina, Cesca, Fabrizia, Benfenati, Fabio

“…RE-1 Silencing Transcription factor (REST) controls several steps in neural development by modulating the expression of a wide range of neural genes…”
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Regulation of neural gene transcription by optogenetic inhibition of the RE1-silencing transcription factor by Paonessa, Francesco, Criscuolo, Stefania, Sacchetti, Silvio, Amoroso, Davide, Scarongella, Helena, Bisogni, Federico Pecoraro, Carminati, Emanuele, Pruzzo, Giacomo, Maragliano, Luca, Cesca, Fabrizia, Benfenati, Fabio

“…Optogenetics provides new ways to activate gene transcription; however, no attempts have been made as yet to modulate mammalian transcription factors. We…”
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Graphene Nanoplatelets Render Poly(3-Hydroxybutyrate) a Suitable Scaffold to Promote Neuronal Network Development by Moschetta, Matteo, Chiacchiaretta, Martina, Cesca, Fabrizia, Roy, Ipsita, Athanassiou, Athanassia, Benfenati, Fabio, Papadopoulou, Evie L., Bramini, Mattia

“…The use of composite biomaterials as innovative bio-friendly neuronal interfaces has been poorly developed so far. Smart strategies to target neuro-pathologies…”
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Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation by del Puerto, Ana, Pose-Utrilla, Julia, Simón-García, Ana, López-Menéndez, Celia, Jiménez, Antonio J., Porlan, Eva, Pajuelo, Luis S. M., Cano-García, Guillermo, Martí-Prado, Beatriz, Sebastián-Serrano, Álvaro, Sánchez-Carralero, Marina P., Cesca, Fabrizia, Schiavo, Giampietro, Ferrer, Isidro, Fariñas, Isabel, Campanero, Miguel R., Iglesias, Teresa

“…Several psychiatric, neurologic and neurodegenerative disorders present increased brain ventricles volume, being hydrocephalus the disease with the major…”
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Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function by Rocchi, Anna, Sacchetti, Silvio, De Fusco, Antonio, Giovedi, Silvia, Parisi, Barbara, Cesca, Fabrizia, Höltje, Markus, Ruprecht, Klemens, Ahnert-Hilger, Gudrun, Benfenati, Fabio

“…Synapsin I is a phosphoprotein that coats the cytoplasmic side of synaptic vesicles and regulates their trafficking within nerve terminals. Autoantibodies…”
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Correction: Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF by Buffolo, Federica, Petrosino, Valentina, Albini, Martina, Moschetta, Matteo, Carlini, Federico, Floss, Thomas, Kerlero de Rosbo, Nicole, Cesca, Fabrizia, Rocchi, Anna, Uccelli, Antonio, Benfenati, Fabio

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The dual action of glioma-derived exosomes on neuronal activity: synchronization and disruption of synchrony by Spelat, Renza, Jihua, Nie, Sánchez Triviño, Cesar Adolfo, Pifferi, Simone, Pozzi, Diletta, Manzati, Matteo, Mortal, Simone, Schiavo, Irene, Spada, Federica, Zanchetta, Melania Eva, Ius, Tamara, Manini, Ivana, Rolle, Irene Giulia, Parisse, Pietro, Millán, Ana P., Bianconi, Ginestra, Cesca, Fabrizia, Giugliano, Michele, Menini, Anna, Cesselli, Daniela, Skrap, Miran, Torre, Vincent

“…Seizures represent a frequent symptom in gliomas and significantly impact patient morbidity and quality of life. Although the pathogenesis of tumor-related…”
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Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis by del Puerto, Ana, Lopez-Fonseca, Coral, Simón-García, Ana, Martí-Prado, Beatriz, Barrios-Muñoz, Ana L., Pose-Utrilla, Julia, López-Menéndez, Celia, Alcover-Sanchez, Berta, Cesca, Fabrizia, Schiavo, Giampietro, Campanero, Miguel R., Fariñas, Isabel, Iglesias, Teresa, Porlan, Eva

“…In the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches sustain the generation of new neurons that integrate into existing…”
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The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes by Scaramuzza, Linda, De Rocco, Giuseppina, Desiato, Genni, Cobolli Gigli, Clementina, Chiacchiaretta, Martina, Mirabella, Filippo, Pozzi, Davide, De Simone, Marco, Conforti, Paola, Pagani, Massimiliano, Benfenati, Fabio, Cesca, Fabrizia, Bedogni, Francesco, Landsberger, Nicoletta

“…MECP2 mutations cause Rett syndrome (RTT), a severe and progressive neurodevelopmental disorder mainly affecting females. Although RTT patients exhibit delayed…”
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Kidins220/ARMS modulates brain morphology and anxiety-like traits in adult mice by Almacellas-Barbanoj, Amanda, Albini, Martina, Satapathy, Annyesha, Jaudon, Fanny, Michetti, Caterina, Krawczun-Rygmaczewska, Alicja, Huang, Huiping, Manago, Francesca, Papaleo, Francesco, Benfenati, Fabio, Cesca, Fabrizia

“…Kinase D interacting substrate of 220 kDa (Kidins220), also known as ankyrin repeat-rich membrane spanning (ARMS), is a transmembrane scaffold protein that…”
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