Search Results - "Cesare Spagnoli, Giulio"
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1
HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker
Published in Neoplasia (New York, N.Y.) (2014)“…Abstract The goal of this study was to determine the frequency of HLA class II antigen expression in colorectal carcinoma (CRC) tumors, its association with…”
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2
CD133+, CD166+CD44+, and CD24+CD44+ Phenotypes Fail to Reliably Identify Cell Populations with Cancer Stem Cell Functional Features in Established Human Colorectal Cancer Cell Lines
Published in Stem cells translational medicine (01-08-2012)“…Increasing evidence that cancers originate from small populations of so‐called cancer stem cells (CSCs), capable of surviving conventional chemotherapies and…”
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3
Expression of cancer-testis antigens MAGE-A4 and MAGE-C1 in oral squamous cell carcinoma
Published in Head & neck (01-08-2012)“…Background Tumor markers are genes or their products expressed exclusively or preferentially in tumor cells and cancer‐testis antigens (CTAs) form a group of…”
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4
Local Activation of the Innate Immune System in Buruli Ulcer Lesions
Published in Journal of investigative dermatology (01-03-2007)“…Buruli ulcer (BU) caused by Mycobacterium ulcerans is a chronic necrotizing disease of the skin and the underlying soft tissue. Fat tissue necrosis accompanied…”
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5
Prognostic Value of "Basal-like" Morphology, Tumor-Infiltrating Lymphocytes and Multi-MAGE-A Expression in Triple-Negative Breast Cancer
Published in International journal of molecular sciences (01-04-2024)“…"Basal-like" (BL) morphology and the expression of cancer testis antigens (CTA) in breast cancer still have unclear prognostic significance. The aim of our…”
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6
Prognostic Significance of Lymphocyte Infiltrate Localization in Triple-Negative Breast Cancer
Published in Journal of personalized medicine (08-06-2022)“…High infiltration by tumor-infiltrating lymphocytes (TILs) is associated with favorable prognosis in different tumor types, but the clinical significance of…”
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7
A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo
Published in Oncoimmunology (04-05-2019)“…CD40 triggering may result in antitumor effects of potentially high clinical relevance. To gain insights important for patient selection and to identify…”
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8
Defective Infiltration of Natural Killer Cells in MICA/B-Positive Renal Cell Carcinoma Involves β2-Integrin-Mediated Interaction
Published in Neoplasia (New York, N.Y.) (01-07-2009)“…We have explored MICA/B expression and its relationship with innate inflammatory infiltrate in renal cell carcinoma (RCC). The expression of MICA/B, CD16,…”
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9
Disseminated single tumor cells as detected by real-time quantitative polymerase chain reaction represent a prognostic factor in patients undergoing surgery for colorectal cancer
Published in Annals of surgery (01-12-2002)“…To evaluate the clinical relevance of real-time quantitative polymerase chain reaction (qPCR) detection of CEA and CK20 transcripts, as potentially related to…”
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Immunohistochemical expression of tumor antigens MAGE-A1, MAGE-A3/4, and NY-ESO-1 in cancerous and benign prostatic tissue
Published in The Prostate (01-01-2006)“…OBJECTIVE To investigate immunohistochemical expression of MAGE‐A and NY‐ESO‐1/LAGE‐1, cancer testis antigens in prostate tissues showing evidence of malignant…”
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11
Expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1 cancer-testis antigens in fetal testis
Published in Acta dermatovenerologica Croatica (2009)“…Immunohistochemical expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1/LAGE-1 cancer testis antigens (CTA) was assessed in 24 fetal testes from 15th to 36th week of…”
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12
Abstract 3695: The interplay between neutrophils &It CDThe interplay between neutrophils and CD8+ cell improves survival in human colorectal cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Purpose: Tumor infiltration by different T lymphocyte subsets is known to be associated with favorable prognosis in colorectal cancer (CRC). Still debated is…”
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13
Critical Evaluation of Transcripts and Long Noncoding RNA Expression Levels in Prostate Cancer Following Radical Prostatectomy
Published in Pathobiology (Basel) (01-12-2023)“…The clinical course of prostate cancer (PCa) is highly variable, ranging from indolent behavior to rapid metastatic progression. The Gleason score is widely…”
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14
Abstract 2821: Gut commensal bacteria modulate functions of tumor-associated neutrophils in human colorectal cancer
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Tumor infiltration by immune cells critically impacts on clinical outcome of human colorectal cancer (CRC). While high densities of CD8+ T cells and T-helper…”
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15
Abstract 2883: Improved generation of central memory CD8+ T cells with CD40L expressing recombinant vaccinia virus
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Immunological memory is the ability of the immune system, upon re-encounter with the same antigen, to respond with greater speed and intensity and constitutes…”
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16
Abstract 2490: CD40 ligand expressing recombinant vaccinia virus (rVV40L) modulation of central memory CD8-mediated immune response
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…In cancer immunotherapy, induction of tumor-reactive CD8+ T cells displaying phenotypic and functional profile of central memory T cells (TCM) is associated…”
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17
Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage
Published in Oncotarget (12-01-2016)“…Acute myeloid leukemia (AML) cells induce, in vitro, NK cell abnormalities (NKCAs) including apoptosis and activating receptor down-regulation. The potential…”
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18
Abstract 3834: Establishment and characterization of 3D multicellular tumor spheroids as preclinical in vitro models of human colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Objective: Multicellular tumor spheroid is a well-known method for three-dimensional in-vitro culture that better represent in-vivo condition. We exploited…”
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19
Defective infiltration of natural killer cells in MICA/B-positive renal cell carcinoma involves beta(2)-integrin-mediated interaction
Published in Neoplasia (New York, N.Y.) (01-07-2009)“…We have explored MICA/B expression and its relationship with innate inflammatory infiltrate in renal cell carcinoma (RCC). The expression of MICA/B, CD16,…”
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Journal Article -
20
Co-expression of cancer testis antigens and topoisomerase 2-alpha in triple negative breast carcinomas
Published in Acta histochemica (01-06-2014)“…Triple negative breast cancers (TNBC) are characterized by aggressive tumor biology, lack of targeted treatments and poor prognosis. Anthracyclins were shown…”
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