Search Results - "Cesar, Isabela da Costa"

Evaluation of the Effects of Maytenus ilicifolia on the Activities of Cytochrome P450 3A and P-glycoprotein by do Nascimento, Sara Batista, de Lima Nascimento, Mariana, de Araújo, Laís Lobato, de Oliveira, Flávio Martins, do Carmo Vieira, Maria, Duarte-Almeida, Joaquim Maurício, Siqueira, João Máximo, da Costa César, Isabela, Derendorf, Hartmut, de Castro, Whocely Victor

“…Maytenus ilicifolia is a Brazilian popular medicine commonly used to treat ulcer and gastritis. Despite the absence of toxicity regarding its consumption,…”
Get more information

Discovery of Lead 2‑Thiazolylhydrazones with Broad-Spectrum and Potent Antifungal Activity by Oliveira, Nereu Junio Cândido, dos Santos Júnior, Valtair Severino, Pierotte, Isabella Campolina, Leocádio, Victor Augusto Teixeira, Santana, Luiz Felipe de Andrade, Marques, Gabriel Vitor de Lima, Protti, Ícaro Ferrari, Braga, Saulo Fehelberg Pinto, Kohlhoff, Markus, Freitas, Túlio Resende, Sabino, Adriano de Paula, Kronenberger, Thales, Gonçalves, José Eduardo, Johann, Susana, Santos, Daniel A., César, Isabela da Costa, Maltarollo, Vinícius Gonçalves, Oliveira, Renata Barbosa

“…Opportunistic fungal infections represent a global health problem, mainly for immunocompromised individuals. New therapeutical options are needed since several…”
Get full text

Influence of PEG coating on the biodistribution and tumor accumulation of pH-sensitive liposomes by Nunes, Shirleide Santos, Fernandes, Renata Salgado, Cavalcante, Carolina Henriques, da Costa César, Isabela, Leite, Elaine Amaral, Lopes, Sávia Caldeira Araújo, Ferretti, Alice, Rubello, Domenico, Townsend, Danyelle M., de Oliveira, Mônica Cristina, Cardoso, Valbert Nascimento, de Barros, André Luís Branco

“…Liposomes are lipid vesicles widely used as nanocarriers in targeted drug delivery systems for therapeutic and/or diagnostic purposes. A strategy to prolong…”
Get full text

Electrochemical evidence of nitrate release from the nitrooxy compound 4-((nitrooxy) methyl)-3-nitrobenzoic acid and its antinociceptive and anti-inflammatory activities in mice by Braga, Alysson Vinícius, da Silva, Roger Ryuler Lisboa, Rodrigues, Ianny Bandeira, Marques, Gabriel Vitor de Lima, Xavier, Andre Felippe de Almeida, Boane, Anastacio, Paiva, Mayara Rodrigues Brandão de, Franco, Pedro Henrique Cavalcanti, Rodrigues, Felipe Fernandes, Melo, Ivo Souza Ferraz, Silva Cunha Júnior, Armando da, César, Isabela da Costa, Goulart, Marília Oliveira Fonseca, Oliveira, Renata Barbosa de, Coelho, Márcio de Matos, Machado, Renes Resende

“…[Display omitted] •Nitrooxy compound 1 (NC1) potentially releases nitric oxide.•Plasma nitrite concentration was increased after administration of NC1.•NC1…”
Get full text

Comparison of HPLC, UV spectrophotometry and potentiometric titration methods for the determination of lumefantrine in pharmaceutical products by César, Isabela da Costa, Nogueira, Fernando Henrique Andrade, Pianetti, Gérson Antônio

“…This paper describes the development and evaluation of a HPLC, UV spectrophotometry and potentiometric titration methods to quantify lumefantrine in raw…”
Get full text

Development and validation of an HPLC method for the simultaneous determination of artesunate and mefloquine hydrochloride in fixed-dose combination tablets by Nogueira, Fernando Henrique Andrade, Reis, Naialy Fernandes Araújo, Chellini, Paula Rocha, César, Isabela da Costa, Pianetti, Gerson Antônio

“…The present study developed and validated an HPLC method for the simultaneous determination of artesunate (AS) and mefloquine hydrochloride (MQ) in fixed-dose…”
Get full text

Simultaneous quantitation of levodopa and 3- O-methyldopa in human plasma by HPLC–ESI-MS/MS: Application for a pharmacokinetic study with a levodopa/benserazide formulation by César, Isabela da Costa, Byrro, Ricardo Martins Duarte, de Santana e Silva Cardoso, Fabiana Fernandes, Mundim, Iram Moreira, de Souza Teixeira, Leonardo, Pontes da Silva, Enikson, Gomes, Sandro Antônio, Bonfim, Ricardo Rodrigues, Pianetti, Gerson Antônio

“…A sensitive and simple method was developed for the quantitation of levodopa and its metabolite 3- O-methyldopa, in human plasma, after oral administration of…”
Get full text

Molecularly imprinted polymer for determination of lumefantrine in human plasma through chemometric-assisted solid-phase extraction and liquid chromatography by da Silva, Pedro Henrique Reis, Diniz, Melina Luiza Vieira, Pianetti, Gerson Antônio, da Costa César, Isabela, Ribeiro e Silva, Maria Elisa Scarpelli, de Souza Freitas, Roberto Fernando, de Sousa, Ricardo Geraldo, Fernandes, Christian

“…Lumefantrine is the first-choice treatment of Falciparum uncomplicated malaria. Recent findings of resistance to lumefantrine has brought attention for the…”
Get full text

Development and Validation of an HPLC Method for Mefloquine Hydrochloride Determination in Tablet Dosage Form by ANDRADE NOGUEIRA, Fernando Henrique, DE PAULA LANA GOULART, Letícia, DA COSTA CESAR, Isabela, MOREIRA DE CAMPOS, Lígia Maria, PIANETTI, Gérson Antônio

“…A simple HPLC method for determination of mefloquine hydrochloride in tablets was developed and validated. The separation was carried out on an Xterra RP18…”
Get full text

Development and validation of a RP-HPLC method for quantification of isoflavone aglycones in hydrolyzed soy dry extracts by da Costa César, Isabela, Braga, Fernão Castro, Soares, Cristina Duarte Vianna, de Aguiar Nunan, Elzíria, Pianetti, Gerson Antônio, Condessa, Felipe Antonacci, Barbosa, Thiago Assis F., Campos, Ligia Maria Moreira

“…Isoflavones are widely used as an alternative treatment to hormone replacement therapy and also for prevention of several chronic diseases, including cancers…”
Get full text

Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes by De Paiva, Mayara Rodrigues Brandão, Lage, Nayara Almeida, Guerra, Maria Carolina Andrade, Mol, Marcos Paulo Gomes, Ribeiro, Marcela Coelho Silva, Fulgêncio, Gustavo De Oliveira, Gomes, Dawidson A., Da Costa César, Isabela, Fialho, Sílvia Ligório, Silva-Cunha, Armando

“…Purpose To assess the in vivo release profile and the retinal toxicity of a poly (lactic-co-glycolic acid) (PLGA) sustained-release sirolimus (SRL)…”
Get full text

Randomized, phase 1/2, double-blind pioglitazone repositioning trial combined with antifungals for the treatment of cryptococcal meningitis – PIO study by Gouveia-Eufrasio, Ludmila, Ribeiro, Noelly Queiroz, Santos, Julliana Ribeiro Alves, da Costa, Marliete Carvalho, Emídio, Elúzia Castro Peres, de Freitas, Gustavo José Cota, do Carmo, Paulo Henrique Fonseca, Miranda, Bárbara Alves, de Oliveira, João Carlos Maia Dornelas, da Silva, Lívia Mara Vitorino, Teixeira Leocádio, Victor Augusto, Randi Magalhães, Vanessa Caroline, Penido, Indiara, Pereira, Leonardo Soares, Rabelo, Lívia Frota, de Almeida Faria, Flávio Augusto, Teixeira Dutra, Maria Rita, Aspahan, Maíra, de Paula, Ludmila, da Silva, Dirce Inês, Tavares Melo, Márcia Gregory, de Andrade Zambelli, Virginia Antunes, Gomes Faraco, André Augusto, da Costa César, Isabela, Alves, Glauciene Prado, da Cunha Melo, Lívia Fulgêncio, de Aguiar Peres, Nalu Teixeira, Santos, Daniel Assis

“…Cryptococcosis affects more than 220,000 patients/year, with high mortality even when the standard treatment [amphotericin B (AMB), 5-flucytosin (5-FC) and…”
Get full text

Determination of Ketoconazole in Capsules by High-Performance Liquid Chromatography and Microbiological Assay by LIMA, Paulo Marcelo Andrade, DUQUE PRADO, Nathalia, SILVA, Maria-Luiza Martins, LOPES DINIZ, Rosiane Dias, MARQUES QUEIROZ, Kelly, DA COSTA CESAR, Isabela, PIANETTI, Gérson Antônio, ASSIS SANTOS, Daniel

“…The development and validation of an HPLC-UV method and a microbiological assay were performed for the analysis of ketoconazole in capsule formulations. The…”
Get full text

Enhancing oral bioavailability of an antifungal thiazolylhydrazone derivative: Development and characterization of a self-emulsifying drug delivery system by Silva, Iara Rinco, Souza, Mateus Araújo Castro e, Machado, Renes Resende, Oliveira, Renata Barbosa de, Leite, Elaine Amaral, César, Isabela da Costa

“…[Display omitted] RN104 (2-[2-(cyclohexylmethylene)hydrazinyl)]-4-phenylthiazole) is a thiazolylhydrazone derivative with prominent antifungal activity. This…”
Get full text

Robustness evaluation of the chromatographic method for the quantitation of lumefantrine using Youden's test by César, Isabela da Costa, Pianetti, Gerson Antônio

“…Youden's test is a reliable method to evaluate the robustness of analytical methods, by means of an experiment design which involves seven analytical…”
Get full text

Quantitation of artemether in pharmaceutical raw material and injections by high performance liquid chromatography by César, Isabela da Costa, Pianetti, Gerson Antônio

“…The quantitation of artemether in both pharmaceutical raw material and injections was carried out by high performance liquid chromatography (HPLC) with…”
Get full text

Rapid Simultaneous Separation of Four Oral Antidiabetic Drugs and Quantitative Determination of Glibenclamide Using Conventional and Fused-Core Silica Columns by Moraes, Laura Maria Fontes Prado, Pianetti, Gerson Antônio, César, Isabela da Costa, Fernandes, Christian

“…Diabetes mellitus is a chronic disease with high and growing prevalence worldwide. Therefore, the development of fast and efficient methods for the QC of…”
Get full text

Validation of a HPLC method for quantification of midazolam in rat plasma: Application during a Maytenus ilicifolia–drug interaction study by Nascimento, Sara Batista, Lima Nascimento, Mariana, Duarte‐Almeida, Joaquim Maurício, Oliveira, Flávio Martins, Carmo Vieira, Maria, Siqueira, João Máximo, Andrade, Frank Pereira, Costa César, Isabela, Castro, Whocely Victor

“…Midazolam (MDZ) is routinely employed as a marker compound of cytochrome P450 3A (CYP3A) activity. Despite the many HPLC–UV methods described to quantify MDZ…”
Get full text

Evaluation of the Effects of Extracts Containing Valeriana officinalis and Piper methysticum on the Activities of Cytochrome P450 3A and P-Glycoprotein by Nascimento, Mariana de Lima, do Nascimento, Sara Batista, Lima, Ednalva de Souza Pereira, de Oliveira, Flávio Martins, Dos Santos, Rafael Rocha, Cesar, Isabela da Costa, de Castro, Whocely Victor

“…This work investigated interactions ascribed to the administration of phytomedicines containing and with conventional drugs. The phytomedicines were…”
Get more information

Simultaneous determination of artemether and lumefantrine in fixed dose combination tablets by HPLC with UV detection by César, Isabela da Costa, Andrade Nogueira, Fernando Henrique, Antônio Pianetti, Gérson

“…This paper describes the development and validation of a HPLC-UV method (210 nm) for the simultaneous quantitation of artemether and lumefantrine in fixed dose…”
Get full text