Search Results - "Cervigne, Nilva K."

A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence by Reis, Patricia P, Waldron, Levi, Perez-Ordonez, Bayardo, Pintilie, Melania, Galloni, Natalie Naranjo, Xuan, Yali, Cervigne, Nilva K, Warner, Giles C, Makitie, Antti A, Simpson, Colleen, Goldstein, David, Brown, Dale, Gilbert, Ralph, Gullane, Patrick, Irish, Jonathan, Jurisica, Igor, Kamel-Reid, Suzanne

“…Oral Squamous Cell Carcinoma (OSCC) is a major cause of cancer death worldwide, which is mainly due to recurrence leading to treatment failure and patient…”
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Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma by Kawahara, Rebeca, Granato, Daniela C, Carnielli, Carolina M, Cervigne, Nilva K, Oliveria, Carine E, Rivera, César, Martinez, César A R, Yokoo, Sami, Fonseca, Felipe P, Lopes, Marcio, Santos-Silva, Alan R, Graner, Edgard, Coletta, Ricardo D, Paes Leme, Adriana Franco

“…Oral squamous cell carcinoma is the most common type of cancer in the oral cavity, representing more than 90% of all oral cancers. The characterization of…”
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Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis by Bufalino, Andreia, Cervigne, Nilva K, de Oliveira, Carine Ervolino, Fonseca, Felipe Paiva, Rodrigues, Priscila Campioni, Macedo, Carolina Carneiro Soares, Sobral, Lays Martin, Miguel, Marcia Costa, Lopes, Marcio Ajudarte, Paes Leme, Adriana Franco, Lambert, Daniel W, Salo, Tuula A, Kowalski, Luiz Paulo, Graner, Edgard, Coletta, Ricardo D

“…Deregulated expression of activin A is reported in several tumors, but its biological functions in oral squamous cell carcinoma (OSCC) are unknown. Here, we…”
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Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma by Reis, Patricia P, Tomenson, Miranda, Cervigne, Nilva K, Machado, Jerry, Jurisica, Igor, Pintilie, Melania, Sukhai, Mahadeo A, Perez-Ordonez, Bayardo, Grénman, Reidar, Gilbert, Ralph W, Gullane, Patrick J, Irish, Jonathan C, Kamel-Reid, Suzanne

“…The tumor suppressor Programmed Cell Death 4 (PDCD4) has been found to be under-expressed in several cancers and associated with disease progression and…”
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Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy by Sadikovic, Bekim, Thorner, Paul, Chilton-Macneill, Susan, Martin, Jeff W, Cervigne, Nilva K, Squire, Jeremy, Zielenska, Maria

“…Human osteosarcoma is the most common pediatric bone tumor. There is limited understanding of the molecular mechanisms underlying osteosarcoma oncogenesis, and…”
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Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma by Dourado, Mauricio Rocha, Korvala, Johanna, Åström, Pirjo, De Oliveira, Carine Ervolino, Cervigne, Nilva K., Mofatto, Luciana Souto, Campanella Bastos, Debora, Pereira Messetti, Ana Camila, Graner, Edgard, Paes Leme, Adriana Franco, Coletta, Ricardo D., Salo, Tuula

“…As one of the most abundant constituents of the tumour microenvironment (TME), cancer-associated fibroblasts (CAF) display critical roles during tumour…”
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Fascin promotes migration and invasion and is a prognostic marker for oral squamous cell carcinoma by Rodrigues, Priscila Campioni, Sawazaki-Calone, Iris, Ervolino de Oliveira, Carine, Soares Macedo, Carolina Carneiro, Dourado, Mauricio Rocha, Cervigne, Nilva K, Miguel, Marcia Costa, Ferreira do Carmo, Andreia, Lambert, Daniel W, Graner, Edgard, Daniela da Silva, Sabrina, Alaoui-Jamali, Moulay A, Paes Leme, Adriana Franco, Salo, Tuula A, Coletta, Ricardo D

“…Oral squamous cell carcinoma (OSCC) prognosis is related to clinical stage and histological grade. However, this stratification needs to be refined. We…”
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Polypodium leucotomos targets multiple aspects of oral carcinogenesis and it is a potential antitumor phytotherapy against tongue cancer growth by Lacerda, Pammela A, Oenning, Luan C, Bellato, Guilherme Cuoghi, Lopes-Santos, Lucilene, Antunes, Natalícia de Jesus, Mariz, Bruno Augusto Linhares Almeida, Teixeira, Gabriela, Vasconcelos, Rafael, Simões, Gustavo Ferreira, de Souza, Ivani Aparecida, Pinto, Clóvis Antônio Lopes, Salo, Tuula, Coletta, Ricardo D, Augusto, Taize M, de Oliveira, Carine Ervolino, Cervigne, Nilva K

“…Oral cancer refers to malignant tumors, of which 90% are squamous cell carcinomas (OSCCs). These malignancies exhibit rapid progression, poor prognosis, and…”
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microRNA evaluation of unknown primary lesions in the head and neck by Barker, Emma V, Cervigne, Nilva K, Reis, Patricia P, Goswami, Rashmi S, Xu, Wei, Weinreb, Ilan, Irish, Jonathan C, Kamel-Reid, Suzanne

“…Unknown primary malignancy in the head and neck is not an infrequent diagnosis for patients with metastatic cervical lymph nodes. Although linked with a…”
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Heparanase 1 Upregulation Promotes Tumor Progression and Is a Predictor of Low Survival for Oral Cancer by Rodrigues, André A. Nimtz, Lopes-Santos, Lucilene, Lacerda, Pammela A., Juste, Mariana F., Mariz, Bruno Augusto, Cajazeiro, Débora C., Giacobbe, Victoria, Borges, Rafael, Casarim, André, Callegari, Giovanna De Sanctis, Claret Arcadipane, Fernando Antônio M., Aprahamian, Ivan, Salo, Tuula Anneli, De Oliveira, Carine Ervolino, Coletta, Ricardo D., Augusto, Taize M., Cervigne, Nilva K.

“…Background: Oral cavity cancer is still an important public health problem throughout the world. Oral squamous cell carcinomas (OSCCs) can be quite aggressive…”
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Optimization and analysis of a quantitative real-time PCR-based technique to determine microRNA expression in formalin-fixed paraffin-embedded samples by Goswami, Rashmi S, Waldron, Levi, Machado, Jerry, Cervigne, Nilva K, Xu, Wei, Reis, Patricia P, Bailey, Denis J, Jurisica, Igor, Crump, Michael R, Kamel-Reid, Suzanne

“…MicroRNAs (miRs) are non-coding RNA molecules involved in post-transcriptional regulation, with diverse functions in tissue development, differentiation, cell…”
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Integrated proteomics identified up-regulated focal adhesion-mediated proteins in human squamous cell carcinoma in an orthotopic murine model by Granato, Daniela C, Zanetti, Mariana R, Kawahara, Rebeca, Yokoo, Sami, Domingues, Romênia R, Aragão, Annelize Z, Agostini, Michelle, Carazzolle, Marcelo F, Vidal, Ramon O, Flores, Isadora L, Korvala, Johanna, Cervigne, Nilva K, Silva, Alan R S, Coletta, Ricardo D, Graner, Edgard, Sherman, Nicholas E, Paes Leme, Adriana F

“…Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of…”
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Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma by Cervigne, Nilva K., Reis, Patricia P., Machado, Jerry, Sadikovic, Bekim, Bradley, Grace, Galloni, Natalie Naranjo, Pintilie, Melania, Jurisica, Igor, Perez-Ordonez, Bayardo, Gilbert, Ralph, Gullane, Patrick, Irish, Jonathan, Kamel-Reid, Suzanne

“…MicroRNAs (miRs) are non-coding RNA molecules involved in cancer initiation and progression. Deregulated miR expression has been implicated in cancer; however,…”
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The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma by Åström, Pirjo, Juurikka, Krista, Hadler-Olsen, Elin S, Svineng, Gunbjørg, Cervigne, Nilva K, Coletta, Ricardo D, Risteli, Juha, Kauppila, Joonas H, Skarp, Sini, Kuttner, Samuel, Oteiza, Ana, Sutinen, Meeri, Salo, Tuula

“…Background: Matrix metalloproteinase-8 (MMP-8) has oncosuppressive properties in various cancers. We attempted to assess MMP-8 function in oral tongue squamous…”
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Peptidomics-Driven Strategy Reveals Peptides and Predicted Proteases Associated With Oral Cancer Prognosis by Neves, Leandro Xavier, Granato, Daniela C., Busso-Lopes, Ariane Fidelis, Carnielli, Carolina M., Patroni, Fábio M. de Sá, De Rossi, Tatiane, Oliveira, Ana Karina, Ribeiro, Ana Carolina P., Brandão, Thais Bianca, Rodrigues, André Nimtz, Lacerda, Pammela Araujo, Uno, Miyuki, Cervigne, Nilva K., Santos-Silva, Alan Roger, Kowalski, Luiz Paulo, Lopes, Marcio Ajudarte, Paes Leme, Adriana F.

“…Protease activity has been associated with pathological processes that can lead to cancer development and progression. However, understanding the pathological…”
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Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis? by Cervigne, Nilva K., Machado, Jerry, Goswami, Rashmi S., Sadikovic, Bekim, Bradley, Grace, Perez-Ordonez, Bayardo, Galloni, Natalie Naranjo, Gilbert, Ralph, Gullane, Patrick, Irish, Jonathan C., Jurisica, Igor, Reis, Patricia P., Kamel-Reid, Suzanne

“…A significant proportion (up to 62%) of oral squamous cell carcinomas (OSCCs) may arise from oral potential malignant lesions (OPMLs), such as leukoplakia…”
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Heparanase 1 involvement in prostate physiopathology by Barbosa, Guilherme O., Cervigne, Nilva K., Carvalho, Hernandes F., Augusto, Taize M.

“…The prostate is a compound exocrine gland of the male reproductive tract universally present in mammals. It is highly responsive to androgen and can be…”
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MicroRNA and protein profiles in invasive versus non-invasive oral tongue squamous cell carcinoma cells in vitro by Korvala, Johanna, Jee, Kowan, Porkola, Emmi, Almangush, Alhadi, Mosakhani, Neda, Bitu, Carolina, Cervigne, Nilva K., Zandonadi, Flávia S., Meirelles, Gabriela V., Leme, Adriana Franco Paes, Coletta, Ricardo D., Leivo, Ilmo, Salo, Tuula

“…Complex molecular pathways regulate cancer invasion. This study overviewed proteins and microRNAs (miRNAs) involved in oral tongue squamous cell carcinoma…”
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HOXA10 controls proliferation, migration and invasion in oral squamous cell carcinoma by Carrera, Manoela, Bitu, Carolina C, de Oliveira, Carine Ervolino, Cervigne, Nilva K, Graner, Edgard, Manninen, Aki, Salo, Tuula, Coletta, Ricardo D

“…Although HOX genes are best known for acting in the regulation of important events during embryogenesis, including proliferation, differentiation and…”
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Neoplastic extracellular matrix environment promotes cancer invasion in vitro by Sundquist, Elias, Renko, Outi, Salo, Sirpa, Magga, Johanna, Cervigne, Nilva K., Nyberg, Pia, Risteli, Juha, Sormunen, Raija, Vuolteenaho, Olli, Zandonadi, Flávia, Paes Leme, Adriana F., Coletta, Ricardo D., Ruskoaho, Heikki, Salo, Tuula

“…The invasion of carcinoma cells is a crucial feature in carcinogenesis. The penetration efficiency not only depends on the cancer cells, but also on the…”
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