Search Results - "Cervantes, Gustavo"

Kynurenine Pathway as a New Target of Cognitive Impairment Induced by Lead Toxicity During the Lactation by Ramirez Ortega, Daniela, Ovalle Rodríguez, Paulina, Pineda, Benjamín, González Esquivel, Dinora F., Ramos Chávez, Lucio Antonio, Vázquez Cervantes, Gustavo I., Roldán Roldán, Gabriel, Pérez de la Cruz, Gonzalo, Díaz Ruiz, Araceli, Méndez Armenta, Marisela, Marcial Quino, Jaime, Gómez Manzo, Saul, Ríos, Camilo, Pérez de la Cruz, Verónica

“…The immature brain is especially vulnerable to lead (Pb 2+ ) toxicity, which is considered an environmental neurotoxin. Pb 2+ exposure during development…”
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Intracranial CNS Manifestations of Myeloid Sarcoma in Patients with Acute Myeloid Leukemia: Review of the Literature and Three Case Reports from the Author's Institution by Cervantes, Gustavo M, Cayci, Zuzan

“…Myeloid sarcoma (MS) of the central nervous system (CNS) is a rare presentation of leukemic mass infiltration outside of the bone marrow. It may involve the…”
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Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas by Arrieta, Víctor A., Gould, Andrew, Kim, Kwang-Soo, Habashy, Karl J., Dmello, Crismita, Vázquez-Cervantes, Gustavo I., Palacín-Aliana, Irina, McManus, Graysen, Amidei, Christina, Gomez, Cristal, Dhiantravan, Silpol, Chen, Li, Zhang, Daniel Y., Saganty, Ruth, Cholak, Meghan E., Pandey, Surya, McCord, Matthew, McCortney, Kathleen, Castro, Brandyn, Ward, Rachel, Muzzio, Miguel, Bouchoux, Guillaume, Desseaux, Carole, Canney, Michael, Carpentier, Alexandre, Zhang, Bin, Miska, Jason M., Lesniak, Maciej S., Horbinski, Craig M., Lukas, Rimas V., Stupp, Roger, Lee-Chang, Catalina, Sonabend, Adam M.

“…Given the marginal penetration of most drugs across the blood-brain barrier, the efficacy of various agents remains limited for glioblastoma (GBM). Here we…”
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Redox and Anti-Inflammatory Properties from Hop Components in Beer-Related to Neuroprotection by Vazquez-Cervantes, Gustavo Ignacio, Ortega, Daniela Ramírez, Blanco Ayala, Tonali, Pérez de la Cruz, Verónica, Esquivel, Dinora Fabiola González, Salazar, Aleli, Pineda, Benjamín

“…Beer is a fermented beverage widely consumed worldwide with high nutritional and biological value due to its bioactive components. It has been described that…”
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A covalent creatine kinase inhibitor ablates glioblastoma migration and sensitizes tumors to oxidative stress by Katz, Joshua L., Geng, Yuheng, Billingham, Leah K., Sadagopan, Nishanth S., DeLay, Susan L., Subbiah, Jay, Chia, Tzu-yi, McManus, Graysen, Wei, Chao, Wang, Hanxiang, Lin, Hanchen, Silvers, Caylee, Boland, Lauren K., Wang, Si, Wan, Hanxiao, Hou, David, Vázquez-Cervantes, Gustavo Ignacio, Arjmandi, Tarlan, Shaikh, Zainab H., Zhang, Peng, Ahmed, Atique U., Tiek, Deanna M., Lee-Chang, Catalina, Chouchani, Edward T., Miska, Jason

“…Glioblastoma is a Grade 4 primary brain tumor defined by therapy resistance, diffuse infiltration, and near-uniform lethality. The underlying mechanisms are…”
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B cell-based therapy produces antibodies that inhibit glioblastoma growth by Wang, Si, Castro, Brandyn A, Katz, Joshua L, Arrieta, Victor, Najem, Hinda, Vazquez-Cervantes, Gustavo I, Wan, Hanxiao, Olson, Ian E, Hou, David, Dapash, Mark, Billingham, Leah K, Chia, Tzu-Yi, Wei, Chao, Rashidi, Aida, Platanias, Leonidas C, McCortney, Kathleen, Horbinski, Craig M, Stupp, Roger, Zhang, Peng, Ahmed, Atique U, Sonabend, Adam M, Heimberger, Amy B, Lesniak, Maciej S, Riviere-Cazaux, Cécile, Burns, Terry, Miska, Jason, Fischietti, Mariafausta, Lee-Chang, Catalina

“…Glioblastoma (GBM) is a highly aggressive and malignant brain tumor with limited therapeutic options and a poor prognosis. Despite current treatments, the…”
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On the Antioxidant Properties of L-Kynurenine: An Efficient ROS Scavenger and Enhancer of Rat Brain Antioxidant Defense by Ramírez Ortega, Daniela, Ugalde Muñiz, Perla Eugenia, Blanco Ayala, Tonali, Vázquez Cervantes, Gustavo Ignacio, Lugo Huitrón, Rafael, Pineda, Benjamín, González Esquivel, Dinora Fabiola, Pérez de la Cruz, Gonzalo, Pedraza Chaverrí, José, Sánchez Chapul, Laura, Gómez-Manzo, Saúl, Pérez de la Cruz, Verónica

“…L-kynurenine (L-KYN) is an endogenous metabolite, that has been used as a neuroprotective strategy in experimental models. The protective effects of L-KYN have…”
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New Immunotherapeutic Approaches for Glioblastoma by Vázquez Cervantes, Gustavo Ignacio, González Esquivel, Dinora F., Gómez-Manzo, Saúl, Pineda, Benjamín, Pérez de la Cruz, Verónica

“…Glioblastoma (GBM) is the most common primary malignant brain tumor with a high mortality rate. The current treatment consists of surgical resection,…”
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Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma by Sathyasaikumar, Korrapati V, Pérez de la Cruz, Verónica, Pineda, Benjamín, Vázquez Cervantes, Gustavo Ignacio, Ramírez Ortega, Daniela, Donley, David W, Severson, Paul L, West, Brian L, Giorgini, Flaviano, Fox, Jonathan H, Schwarcz, Robert

“…Kynurenine 3-monooxygenase (KMO), a key player in the kynurenine pathway (KP) of tryptophan degradation, regulates the synthesis of the neuroactive metabolites…”
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EphA2 Mutation in Lung Squamous Cell Carcinoma Promotes Increased Cell Survival, Cell Invasion, Focal Adhesions, and Mammalian Target of Rapamycin Activation by Faoro, Leonardo, Singleton, Patrick A., Cervantes, Gustavo M., Lennon, Frances E., Choong, Nicholas W., Kanteti, Rajani, Ferguson, Benjamin D., Husain, Aliya N., Tretiakova, Maria S., Ramnath, Nithya, Vokes, Everett E., Salgia, Ravi

“…Non-small cell lung cancer (NSCLC) has a poor prognosis and improved therapies are needed. Expression of EphA2 is increased in NSCLC metastases. In this study,…”
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Kynureninase Promotes Immunosuppression and Predicts Survival in Glioma Patients: In Silico Data Analyses of the Chinese Glioma Genome Atlas (CGGA) and of the Cancer Genome Atlas (TCGA) by Pérez de la Cruz, Gonzalo, Pérez de la Cruz, Verónica, Navarro Cossio, Javier, Vázquez Cervantes, Gustavo Ignacio, Salazar, Aleli, Orozco Morales, Mario, Pineda, Benjamin

“…Kynureninase (KYNU) is a kynurenine pathway (KP) enzyme that produces metabolites with immunomodulatory properties. In recent years, overactivation of KP has…”
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Antigen-presenting B cells promote TCF-1 + PD1 - stem-like CD8 + T-cell proliferation in glioblastoma by Hou, David, Wan, Hanxiao, Katz, Joshua L, Wang, Si, Castro, Brandyn A, Vazquez-Cervantes, Gustavo I, Arrieta, Victor A, Dhiantravan, Silpol, Najem, Hinda, Rashidi, Aida, Chia, Tzu-Yi, Arjmandi, Tarlan, Collado, Jimena, Billingham, Leah, Lopez-Rosas, Aurora, Han, Yu, Sonabend, Adam M, Heimberger, Amy B, Zhang, Peng, Miska, Jason, Lee-Chang, Catalina

“…Understanding the spatial relationship and functional interaction of immune cells in glioblastoma (GBM) is critical for developing new therapeutics that…”
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Lipoteichoic acid reduces antioxidant enzymes in H9c2 cells by Fernández-Rojas, Berenice, Vázquez-Cervantes, Gustavo I., Pedraza-Chaverri, José, Gutiérrez-Venegas, Gloria

“…[Display omitted] •Lipoteichoic acid (LTA) reduced the levels of the antioxidant enzymes in H9c2 cells.•LTA from Streptococcus sanguinis induced ROS production…”
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The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target by Ferguson, Benjamin D, Liu, Ren, Rolle, Cleo E, Tan, Yi-Hung Carol, Krasnoperov, Valery, Kanteti, Rajani, Tretiakova, Maria S, Cervantes, Gustavo M, Hasina, Rifat, Hseu, Robyn D, Iafrate, A John, Karrison, Theodore, Ferguson, Mark K, Husain, Aliya N, Faoro, Leonardo, Vokes, Everett E, Gill, Parkash S, Salgia, Ravi

“…Despite progress in locoregional and systemic therapies, patient survival from lung cancer remains a challenge. Receptor tyrosine kinases are frequently…”
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Mechanisms Associated with Cognitive and Behavioral Impairment Induced by Arsenic Exposure by Vázquez Cervantes, Gustavo Ignacio, González Esquivel, Dinora Fabiola, Ramírez Ortega, Daniela, Blanco Ayala, Tonali, Ramos Chávez, Lucio Antonio, López-López, Humberto Emanuel, Salazar, Alelí, Flores, Itamar, Pineda, Benjamín, Gómez-Manzo, Saúl, Pérez de la Cruz, Verónica

“…Arsenic (As) is a metalloid naturally present in the environment, in food, water, soil, and air; however, its chronic exposure, even with low doses, represents…”
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Bioinformatic Analysis of Kynurenine Pathway Enzymes and Their Relationship with Glioma Hallmarks by Vázquez Cervantes, Gustavo Ignacio, Navarro Cossio, Javier Ángel, Pérez de la Cruz, Gonzalo, Salazar, Aleli, Pérez de la Cruz, Verónica, Pineda, Benjamin

“…Indoleamine dioxygenase (IDO), a rate limiting enzyme of the tryptophan catabolism through the kynurenine pathway (KP), has been related with a lower survival…”
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Lower Gastrointestinal Bleeding Associated With Variceal Hemorrhoidal Disease in a Patient With Pan-Colonic Varices by Cervantes Millán, Gustavo, Tejeda Saenz, Rebeca Marina, López Acosta, Maria E, Perez Aguirre, Javier

“…Colonic varices are a rare condition primarily caused by portal hypertension associated with conditions such as cirrhosis or hepatocellular carcinoma…”
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The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation by Andérica-Romero, Ana Cristina, Hernández-Damián, Jacqueline, Vázquez-Cervantes, Gustavo Ignacio, Torres, Ismael, González-Herrera, Irma Gabriela, Pedraza-Chaverri, José

“…It was explored the cytoprotective and antioxidant effect of MLN4924, a specific inhibitor of Nedd8-activating enzyme (NAE), against hydrogen peroxide…”
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CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases by Tan, Yi-Hung Carol, Krishnaswamy, Soundararajan, Nandi, Suvobroto, Kanteti, Rajani, Vora, Sapana, Onel, Kenan, Hasina, Rifat, Lo, Fang-Yi, El-Hashani, Essam, Cervantes, Gustavo, Robinson, Matthew, Hsu, Han-Shui, Kales, Stephen C, Lipkowitz, Stanley, Karrison, Theodore, Sattler, Martin, Vokes, Everett E, Wang, Yi-Ching, Salgia, Ravi

“…Non-small cell lung cancer (NSCLC) is a heterogeneous group of disorders with a number of genetic and proteomic alterations. c-CBL is an E3 ubiquitin ligase…”
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Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas by Vázquez Cervantes, Gustavo Ignacio, Pineda, Benjamín, Ramírez Ortega, Daniela, Salazar, Alelí, González Esquivel, Dinora Fabiola, Rembao, Daniel, Zavala Vega, Sergio, Gómez-Manzo, Saúl, Pérez de la Cruz, Gonzalo, Pérez de la Cruz, Verónica

“…Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor. The enzyme indoleamine-2,3-dioxygenase (IDO), which participates in the…”
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