Organochlorine pesticides in serum and adipose tissue of pregnant women in Southern Spain giving birth by cesarean section

Organochlorine pesticides in serum and adipose tissue of pregnant women in Southern Spain giving birth by cesarean section

Since the appearance of DDT, increasingly potent insecticides have been developed to overcome the resistance developed by insects to successive products. Pesticides are also used in public health programs to control disease vectors. Despite legislation to control the use of certain products, they re...

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Bibliographic Details
Published in:The Science of the total environment Vol. 372; no. 1; pp. 32 - 38
Main Authors: Jimenez Torres, M., Campoy Folgoso, C., Cañabate Reche, F., Rivas Velasco, A., Cerrillo Garcia, I., Mariscal Arcas, M., Olea-Serrano, F.
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 15-12-2006
Subjects:
Adipose tissue
Adipose Tissue - metabolism
Adult
Cesarean Section
Environmental Monitoring
Environmental Pollutants - analysis
Environmental Pollutants - blood
Female
Fetal Blood - chemistry
Humans
Hydrocarbons, Chlorinated - analysis
Hydrocarbons, Chlorinated - blood
Maternal Exposure
Organochlorine compounds
Parturition
Pesticides - analysis
Pesticides - blood
Pregnancy
Spain
Umbilical cord serum
Spain
Organochlorine compounds
Umbilical cord serum
Adipose tissue
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Summary:Since the appearance of DDT, increasingly potent insecticides have been developed to overcome the resistance developed by insects to successive products. Pesticides are also used in public health programs to control disease vectors. Despite legislation to control the use of certain products, they repeatedly appear in the adipose tissue, milk and serum of human populations. The present study determined the presence of organochlorine molecules in the adipose tissue, serum, and umblical cord of women giving birth by cesarean section in order to establish a possible correlation in organochlorine molecule content between these biological compartments and to examine fetal exposure to molecules with hormonal effects. Presence of nine organochlorines was detected by GC/ECD and confirmed by GC/MS. Highly significant differences (p<0.000) were observed between adipose tissue and maternal serum in concentrations of lindane, HCB, DDE, DDD, and endosulfan but not (p>0.5) in concentrations of endosulfan II or endosulfan sulfate. Only DDE concentrations differed (p<0.001) between maternal serum and umbilical cord serum. An association between pp'DDE and op'DDT was observed in maternal serum (p<0.094). An association in pp'DDE and pp'DDD content was found between adipose tissue and umbilical cord serum, and in pp'DDT content between adipose tissue and maternal serum. Results obtained indicate that exposure can be measured solely in serum when relatively high concentrations of pesticides are present.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0048-9697
1879-1026
DOI:10.1016/j.scitotenv.2006.07.009