Search Results - "Cerqueira, Débora M."

Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury by Chiba, Takuto, Cerqueira, Débora M, Li, Yao, Bodnar, Andrew J, Mukherjee, Elina, Pfister, Katherine, Phua, Yu Leng, Shaikh, Kai, Sanders, Brandon T, Hemker, Shelby L, Pagano, Patrick J, Wu, Yijen L, Ho, Jacqueline, Sims-Lucas, Sunder

“…Damage to the renal microvasculature is a hallmark of renal ischemia-reperfusion injury (IRI)-mediated AKI. The miRNA cluster (encoding , , , , , and )…”
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Isoquercitrin Suppresses Colon Cancer Cell Growth in Vitro by Targeting the Wnt/β-Catenin Signaling Pathway by Amado, Nathália G., Predes, Danilo, Fonseca, Barbara F., Cerqueira, Débora M., Reis, Alice H., Dudenhoeffer, Ana C., Borges, Helena L., Mendes, Fábio A., Abreu, Jose G.

“…Flavonoids are plant-derived polyphenolic molecules that have potential biological effects including anti-oxidative, anti-inflammatory, anti-viral, and…”
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Role of the CCL5 and Its Receptor, CCR5, in the Genesis of Aldosterone-Induced Hypertension, Vascular Dysfunction, and End-Organ Damage by Costa, Rafael M, Cerqueira, Débora M, Bruder-Nascimento, Ariane, Alves, Juliano V, Awata, Wanessa M C, Singh, Shubhnita, Kufner, Alexander, Prado, Douglas S, Johny, Ebin, Cifuentes-Pagano, Eugenia, Hawse, William F, Dutta, Partha, Pagano, Patrick J, Ho, Jacqueline, Bruder-Nascimento, Thiago

“…Aldosterone has been described to initiate cardiovascular diseases by triggering exacerbated sterile vascular inflammation. The functions of CCL5 (C-C motif…”
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Single-cell RNA sequencing reveals differential cell cycle activity in key cell populations during nephrogenesis by Bais, Abha S., Cerqueira, Débora M., Clugston, Andrew, Bodnar, Andrew J., Ho, Jacqueline, Kostka, Dennis

“…The kidney is a complex organ composed of more than 30 terminally differentiated cell types that all are required to perform its numerous homeostatic…”
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Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development by Cerqueira, Débora M., Bodnar, Andrew J., Leng Phua, Yu, Freer, Rachel, Hemker, Shelby L., Walensky, Loren D., Hukriede, Neil A., Ho, Jacqueline

“…ABSTRACT Low nephron endowment at birth has been associated with an increased risk for developing hypertension and chronic kidney disease. We demonstrated in…”
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Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma by Anslow, Melissa J., Bodnar, Andrew J., Cerqueira, Débora M., Bushnell, Daniel, Shrom, Brynn E., Sims-Lucas, Sunder, Bates, Carlton M., Ho, Jacqueline

“…Background Vesicoureteral reflux (VUR), backflow of urine into the kidney, is associated with urinary tract infections and chronic kidney disease. Integrity of…”
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MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney by Romaker, Daniel, Kumar, Vikash, Cerqueira, Débora M., Cox, Ryan M., Wessely, Oliver

“…MicroRNAs (miRNAs) are major posttranscriptional regulators of a wide variety of biological processes. However, redundancy among most miRNAs has made it…”
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Deletion of hypoxia‐responsive microRNA‐210 results in a sex‐specific decrease in nephron number by Hemker, Shelby L., Cerqueira, Débora M., Bodnar, Andrew J., Cargill, Kasey R., Clugston, Andrew, Anslow, Melissa J., Sims‐Lucas, Sunder, Kostka, Dennis, Ho, Jacqueline

“…Low nephron number results in an increased risk of developing hypertension and chronic kidney disease. Intrauterine growth restriction is associated with a…”
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In utero exposure to maternal diabetes impairs nephron progenitor differentiation by Cerqueira, Débora M, Hemker, Shelby L, Bodnar, Andrew J, Ortiz, Daniella M, Oladipupo, Favour O, Mukherjee, Elina, Gong, Zhenwei, Appolonia, Corynn, Muzumdar, Radhika, Sims-Lucas, Sunder, Ho, Jacqueline

“…The incidence of diabetes mellitus has significantly increased among women of childbearing age, and it has been shown that prenatal exposure to maternal…”
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Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus by White, Jeffrey T, Zhang, Bo, Cerqueira, Débora M, Tran, Uyen, Wessely, Oliver

“…Podocytes are highly specialized cells in the vertebrate kidney. They participate in the formation of the size-exclusion barrier of the glomerulus/glomus and…”
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Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts by Cerqueira, Débora M., Tran, Uyen, Romaker, Daniel, Abreu, José G., Wessely, Oliver

“…The kidney is a homeostatic organ required for waste excretion and reabsorption of water, salts and other macromolecules. To this end, a complex series of…”
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Isoquercitrin isolated from Hyptis fasciculata reduces glioblastoma cell proliferation and changes β-catenin cellular localization by Amado, Nathália G, Cerqueira, Débora M, Menezes, Fabio S, Mendes da Silva, Joaquim Fernando, Neto, Vivaldo Moura, Abreu, Jose G

“…Isoquercitrin isolated from the aerial parts of Hyptis fasciculata was evaluated according to its capacity to interfere with glioblastoma (Gbm) cell growth…”
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Flavonoids: Potential Wnt/beta-catenin signaling modulators in cancer by Amado, Nathália G., Fonseca, Bárbara F., Cerqueira, Débora M., Neto, Vivaldo Moura, Abreu, José G.

“…Flavonoids are polyphenolic compounds found throughout the plant kingdom. They occur in every organ but are usually concentrated in leaves and flowers. During…”
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The bigger the better: determining nephron size in kidney by Wessely, Oliver, Cerqueira, Débora M., Tran, Uyen, Kumar, Vikash, Hassey, Jessie M., Romaker, Daniel

“…The main functions of the kidney are to excrete metabolic waste products and actively reabsorb essential molecules such as amino acids, ions, glucose and…”
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Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro by Fonseca, Barbara F, Predes, Danilo, Cerqueira, Debora M, Reis, Alice H, Amado, Nathalia G, Cayres, Marina C L, Kuster, Ricardo M, Oliveira, Felipe L, Mendes, Fabio A, Abreu, Jose G

“…Overactivation of the Wnt/β-catenin pathway in adult tissues has been implicated in many diseases, such as colorectal cancer. Finding chemical substances that…”
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Kinin-B2 Receptor Activity Determines the Differentiation Fate of Neural Stem Cells by Trujillo, Cleber A., Negraes, Priscilla D., Schwindt, Telma T., Lameu, Claudiana, Carromeu, Cassiano, Muotri, Alysson R., Pesquero, João B., Cerqueira, Débora M., Pillat, Micheli M., de Souza, Héllio D.N., Turaça, Lauro T., Abreu, José G., Ulrich, Henning

“…Bradykinin is not only important for inflammation and blood pressure regulation, but also involved in neuromodulation and neuroprotection. Here we describe…”
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Plasma membrane cholesterol depletion disrupts prechordal plate and affects early forebrain patterning by Reis, Alice H., Almeida-Coburn, Karla L., Louza, Mariana P., Cerqueira, Débora M., Aguiar, Diego P., Silva-Cardoso, Livia, Mendes, Fábio A., Andrade, Leonardo R., Einicker-Lamas, Marcelo, Atella, Georgia C., Brito, José M., Abreu, José G.

“…Cholesterol-rich membrane microdomains (CRMMs) are specialized structures that have recently gained much attention in cell biology because of their involvement…”
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MicroRNA-19 is regulated by aldosterone in a sex-specific manner to alter kidney sodium transport by Farrell, Corinne E, Liu, Xiaoning, Yagan, Nejla Ozbaki, Suda, Amanda C, Cerqueira, Debora M, Bodnar, Andrew J, Kashlan, Ossama B, Subramanya, Arohan R, Ho, Jacqueline, Butterworth, Michael B

“…A key regulator of blood pressure homeostasis is the steroid hormone aldosterone, which is released as the final signaling hormone of the…”
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Expression pattern of genes related to lipid rafts formation during Xenopus laevis development by Nathália, Amado G., Cerqueira, Débora M., Abreu, José G.

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Derricin and Derricidin Inhibit Wnt/[beta]-Catenin Signaling and Suppress Colon Cancer Cell Growth In Vitro by Fonseca, Barbara F, Predes, Danilo, Cerqueira, Debora M, Reis, Alice H, Amado, Nathalia G, Cayres, Marina C. L, Kuster, Ricardo M, Oliveira, Felipe L, Mendes, Fabio A, Abreu, Jose G

“…Overactivation of the Wnt/[beta]-catenin pathway in adult tissues has been implicated in many diseases, such as colorectal cancer. Finding chemical substances…”
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