Search Results - "Cerny, Natacha"

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    Trypanocidal Activity of Four Sesquiterpene Lactones Isolated from Asteraceae Species by Elso, Orlando G, Bivona, Augusto E, Sanchez Alberti, Andrés, Cerny, Natacha, Fabian, Lucas, Morales, Celina, Catalán, César A N, Malchiodi, Emilio L, Cazorla, Silvia I, Sülsen, Valeria P

    Published in Molecules (Basel, Switzerland) (25-04-2020)
    “…The sesquiterpene lactones eupatoriopicrin, estafietin, eupahakonenin B and minimolide have been isolated from Argentinean Astearaceae species and have been…”
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    Journal Article
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    Cruzipain and Its Physiological Inhibitor, Chagasin, as a DNA-Based Therapeutic Vaccine Against Trypanosoma cruzi by Cerny, Natacha, Bivona, Augusto Ernesto, Sanchez Alberti, Andrés, Trinitario, Sebastián Nicolás, Morales, Celina, Cardoso Landaburu, Alejandro, Cazorla, Silvia Inés, Malchiodi, Emilio Luis

    Published in Frontiers in immunology (09-10-2020)
    “…Chagas disease caused by the protozoan parasite is endemic in 21 Latin American countries and the southern United States and now is spreading into several…”
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    Journal Article
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    Oxonitrogenated Derivatives of Eremophilans and Eudesmans: Antiproliferative and Anti- Trypanosoma cruzi Activity by Beer, María F, Reta, Guillermo F, Puerta, Adrián, Bivona, Augusto E, Alberti, Andrés Sánchez, Cerny, Natacha, Malchiodi, Emilio L, Tonn, Carlos E, Padrón, José M, Sülsen, Valeria P, Donadel, Osvaldo J

    Published in Molecules (Basel, Switzerland) (10-05-2022)
    “…Cancer is one of the most important causes of death worldwide. Solid tumors represent the vast majority of cancers (>90%), and the chemotherapeutic agents used…”
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    Activity of Estafietin and Analogues on Trypanosoma cruzi and Leishmania braziliensis by Sülsen, Valeria P, Lizarraga, Emilio F, Elso, Orlando G, Cerny, Natacha, Sanchez Alberti, Andrés, Bivona, Augusto E, Malchiodi, Emilio L, Cazorla, Silvia I, Catalán, César A N

    Published in Molecules (Basel, Switzerland) (28-03-2019)
    “…Sesquiterpene lactones are naturally occurring compounds mainly found in the Asteraceae family. These types of plant metabolites display a wide range of…”
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    Journal Article
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    Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine by Bivona, Augusto E, Sánchez Alberti, Andrés, Matos, Marina N, Cerny, Natacha, Cardoso, Alejandro C, Morales, Celina, González, Germán, Cazorla, Silvia I, Malchiodi, Emilio L

    Published in PLoS neglected tropical diseases (01-03-2018)
    “…Chagas disease, also known as American Trypanosomiasis, is a chronic parasitic disease caused by the flagellated protozoan Trypanosoma cruzi that affects about…”
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    Journal Article
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    Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection by Sanchez Alberti, Andrés, Bivona, Augusto E., Cerny, Natacha, Schulze, Kai, Weißmann, Sebastian, Ebensen, Thomas, Morales, Celina, Padilla, Angel M., Cazorla, Silvia I., Tarleton, Rick L., Guzmán, Carlos A., Malchiodi, Emilio L.

    Published in npj vaccines (10-04-2017)
    “…The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in…”
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    Journal Article
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    Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action by Beer, María F, Bivona, Augusto E, Sánchez Alberti, Andrés, Cerny, Natacha, Reta, Guillermo F, Martín, Víctor S, Padrón, José M, Malchiodi, Emilio L, Sülsen, Valeria P, Donadel, Osvaldo J

    Published in Molecules (Basel, Switzerland) (20-03-2019)
    “…Cancer is one of the most important causes of death worldwide. Solid tumors represent the great majority of cancers (>90%) and the chemotherapeutic agents used…”
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    Journal Article
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    In Vitro, In Vivo, and In Silico Studies of Cumanin Diacetate as a Potential Drug against Trypanosoma cruzi Infection by Sánchez Alberti, Andrés, Beer, María F, Cerny, Natacha, Bivona, Augusto E, Fabian, Lucas, Morales, Celina, Moglioni, Albertina, Malchiodi, Emilio L, Donadel, Osvaldo J, Sülsen, Valeria P

    Published in ACS omega (11-01-2022)
    “…The sesquiterpene lactones cumanin, helenalin, and hymenin and their semisynthetic derivatives were evaluated against Trypanosoma cruzi epimastigotes. The…”
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    Journal Article
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    Chagas disease vaccine design: the search for an efficient Trypanosoma cruzi immune-mediated control by Bivona, Augusto E., Alberti, Andrés Sánchez, Cerny, Natacha, Trinitario, Sebastián N., Malchiodi, Emilio L.

    “…Chagas disease is currently endemic to 21 Latin-American countries and has also become a global concern because of globalization and mass migration of…”
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    Journal Article
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    In silico toxicologic profile and in vivo trypanocidal activity of estafietin, a sesquiterpene lactone isolated from Stevia alpina Griseb by Elso, Orlando G, Cerny, Natacha, Laurella, Laura C, Bivona, Augusto E, Sánchez Alberti, Andrés, Morales, Celina, Catalán, Cesar A N, Malchiodi, Emilio L, Sülsen, Valeria P

    Published in Natural product research (01-02-2024)
    “…Chagas disease is an infection caused by the protozoan affecting 6-8 million people worldwide. Only two drugs are available for its treatment, having a limited…”
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    Journal Article
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    Oral Multicomponent DNA Vaccine Delivered by Attenuated Salmonella Elicited Immunoprotection Against American Trypanosomiasis by Cazorla, Silvia I., Matos, Marina N., Cerny, Natacha, Ramirez, Carolina, Alberti, Andrés Sanchez, Bivona, Augusto E., Morales, Celina, Guzmán, Carlos A., Malchiodi, Emilio L.

    Published in The Journal of infectious diseases (01-03-2015)
    “…We have reported that attenuated Salmonella (S) carrying plasmids encoding the cysteine protease cruzipain (Cz) protects against Trypanosoma cruzi infection…”
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    Journal Article
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    Trypanosoma cruzi 80 kDa prolyl oligopeptidase by Morales, Celina, Matos, Marina N, Malchiodi, Emilio L, Cazorla, Silvia I, Bivona, Augusto E, González, Germán, Cerny, Natacha, Sánchez Alberti, Andrés, Cardoso, Alejandro C

    Published in PLoS neglected tropical diseases (30-03-2018)
    “…Background Chagas disease, also known as American Trypanosomiasis, is a chronic parasitic disease caused by the flagellated protozoan Trypanosoma cruzi that…”
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    Journal Article
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    Attenuated Salmonella sp. as a DNA Delivery System for Trypanosoma cruzi Antigens by Bivona, Augusto E, Cerny, Natacha, Alberti, Andrés Sánchez, Cazorla, Silvia I, Malchiodi, Emilio L

    “…Chagas disease is an important neglected disease affecting thousands of people in the Americas. Novel strategies for prophylactic and therapeutic vaccines…”
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    Journal Article
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    Coadministration of cruzipain and GM-CSF DNAs, a new immunotherapeutic vaccine against Trypanosoma cruzi infection by Cerny, Natacha, Sánchez Alberti, Andrés, Bivona, Augusto E, De Marzi, Mauricio C, Frank, Fernanda M, Cazorla, Silvia I, Malchiodi, Emilio L

    Published in Human vaccines & immunotherapeutics (01-02-2016)
    “…Therapeutic vaccine research and development are especially important in Chagas disease considering the characteristics of the chronic infection and the number…”
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    Journal Article