Search Results - "Cerný, L"
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Iterative Assembly of Two Separate Polyketide Chains by the Same Single-Module Bacterial Polyketide Synthase in the Biosynthesis of HSAF
Published in Angewandte Chemie International Edition (14-07-2014)“…Antifungal HSAF (heat‐stable antifungal factor, dihydromaltophilin) is a polycyclic tetramate macrolactam from the biocontrol agent Lysobacter enzymogenes. Its…”
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Overexpression of GalNAc-transferase GalNAc-T3 promotes pancreatic cancer cell growth
Published in Oncogene (08-12-2011)“…O -linked glycans of secreted and membrane-bound proteins have an important role in the pathogenesis of pancreatic cancer by modulating immune responses,…”
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3
A transcriptomal analysis of bovine oviductal epithelial cells collected during the follicular phase versus the luteal phase of the estrous cycle
Published in Reproductive biology and endocrinology (05-08-2015)“…Reproductive success depends on a functional oviduct for gamete storage, maturation, fertilization, and early embryonic development. The ovarian-derived…”
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4
Comparison of modification sites formed on human serum albumin at various stages of glycation
Published in Clinica chimica acta (30-01-2011)“…Many of the complications encountered during diabetes can be linked to the non-enzymatic glycation of proteins, including human serum albumin (HSA). However,…”
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A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity
Published in Nature (17-05-2007)“…The bacterial plant pathogen Pseudomonas syringae injects effector proteins into host cells through a type III protein secretion system to cause disease. The…”
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6
Phosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells
Published in The American journal of pathology (01-02-2008)“…Critical to the proper maintenance of blood-brain-barrier (BBB) integrity are the endothelial tight junctions (TJs). Posttranslational modifications of…”
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7
Structure Function Analysis of an ADP-ribosyltransferase Type III Effector and Its RNA-binding Target in Plant Immunity
Published in The Journal of biological chemistry (16-12-2011)“…The Pseudomonas syringae type III effector HopU1 is a mono-ADP-ribosyltransferase that is injected into plant cells by the type III protein secretion system…”
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8
Tau‐tubulin kinase 1 (TTBK1), a neuron‐specific tau kinase candidate, is involved in tau phosphorylation and aggregation
Published in Journal of neurochemistry (01-09-2006)“…Neurofibrillary tangles, which are major pathological hallmarks of Alzheimer's disease (AD), are composed of paired helical filaments (PHFs) containing…”
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Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas
Published in Epigenetics (16-05-2010)“…Polycomb group proteins play an essential role in the maintenance of cell identity and the regulation of development in both animals and plants. The Polycomb…”
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Characterization of glycation adducts on human serum albumin by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Published in Clinica chimica acta (01-10-2007)“…Non-enzymatic glycation of human serum albumin (HSA) is associated with the long-term complications of diabetes. We examined the structure and location of…”
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Unusual Activities of the Thioesterase Domain for the Biosynthesis of the Polycyclic Tetramate Macrolactam HSAF in Lysobacter enzymogenes C3
Published in Biochemistry (Easton) (10-01-2012)“…HSAF is an antifungal natural product with a new mode of action. A rare bacterial iterative PKS-NRPS assembles the HSAF skeleton. The biochemical…”
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12
Estrogen Receptor Alpha (ESR1)-Dependent Regulation of the Mouse Oviductal Transcriptome
Published in PloS one (25-01-2016)“…Estrogen receptor-α (ESR1) is an important transcriptional regulator in the mammalian oviduct, however ESR1-dependent regulation of the transcriptome of this…”
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13
Knockdown of the cellular protein LRPPRC attenuates HIV-1 infection
Published in PloS one (12-07-2012)“…HIV-1 exploits numerous host cellular pathways for productive infection. To identify novel factors involved in HIV-1 replication, HIV-1 integrase and matrix…”
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Paramecium bursaria Chlorella Virus 1 Proteome Reveals Novel Architectural and Regulatory Features of a Giant Virus
Published in Journal of Virology (01-08-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
Activities within an Ecological, Relationship-Based Model of Children’s Subjective Well-Being
Published in Child indicators research (01-04-2019)“…This paper describes the epistemological approach, methodological considerations and results of a qualitative study examining activity participation in the…”
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Transient sampling of aggregation‐prone conformations causes pathogenic instability of a parkinsonian mutant of DJ‐1 at physiological temperature
Published in Protein science (01-10-2015)“…Various missense mutations in the cytoprotective protein DJ‐1 cause rare forms of inherited parkinsonism. One mutation, M26I, diminishes DJ‐1 protein levels in…”
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Phosphorylation of MUC1 by Met Modulates Interaction with p53 and MMP1 Expression
Published in The Journal of biological chemistry (03-10-2008)“…MUC1, a transmembrane mucin, is a key modulator of several signaling pathways that affect oncogenesis, motility, and cell morphology. The interaction of MUC1…”
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Mdm2 Binds to Nbs1 at Sites of DNA Damage and Regulates Double Strand Break Repair
Published in The Journal of biological chemistry (13-05-2005)“…Mdm2 directly regulates the p53 tumor suppressor. However, Mdm2 also has p53-independent activities, and the pathways that mediate these functions are…”
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Reaction Mechanism, Evolutionary Analysis, and Role of Zinc in Drosophila Methionine-R-sulfoxide Reductase
Published in The Journal of biological chemistry (04-10-2002)“…Methionine residues in proteins are susceptible to oxidation, and the resulting methionine sulfoxides can be reduced back to methionines by…”
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Determining the Biosynthetic Sequence in the Early Steps of the Fumonisin Pathway by Use of Three Gene-Disruption Mutants of Fusarium verticillioides
Published in Journal of agricultural and food chemistry (19-05-2004)“…Fumonisins are polyketide-derived mycotoxins produced by Fusarium verticillioides, a fungal pathogen of corn plants. Although a gene cluster for the…”
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