Search Results - "Cermak, Jennifer M."

Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes by Biason-Lauber, Anna, Böni-Schnetzler, Marianne, Hubbard, Basil P., Bouzakri, Karim, Brunner, Andrea, Cavelti-Weder, Claudia, Keller, Cornelia, Meyer-Böni, Monika, Meier, Daniel T., Brorsson, Caroline, Timper, Katharina, Leibowitz, Gil, Patrignani, Andrea, Bruggmann, Remy, Boily, Gino, Zulewski, Henryk, Geier, Andreas, Cermak, Jennifer M., Elliott, Peter, Ellis, James L., Westphal, Christoph, Knobel, Urs, Eloranta, Jyrki J., Kerr-Conte, Julie, Pattou, François, Konrad, Daniel, Matter, Christian M., Fontana, Adriano, Rogler, Gerhard, Schlapbach, Ralph, Regairaz, Camille, Carballido, José M., Glaser, Benjamin, McBurney, Michael W., Pociot, Flemming, Sinclair, David A., Donath, Marc Y.

“…Type 1 diabetes is caused by autoimmune-mediated β cell destruction leading to insulin deficiency. The histone deacetylase SIRT1 plays an essential role in…”
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Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice by Beretta, Martina, Dai, Yumin, Olzomer, Ellen M, Vancuylenburg, Calum S, Santiago-Rivera, José A, Philp, Ashleigh M, Hargett, Stefan R, Li, Keyong, Shah, Divya P, Chen, Sing-Young, Alexopoulos, Stephanie J, Li, Catherine, Harris, Thurl E, Lee, Brendan, Wathier, Michel, Cermak, Jennifer M, Tucker, Simon P, Turner, Nigel, Bayliss, Douglas A, Philp, Andrew, Byrne, Frances L, Santos, Webster L, Hoehn, Kyle L

“…Excess body fat is a risk factor for metabolic diseases and is a leading preventable cause of morbidity and mortality worldwide. There is a strong need to find…”
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Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma by Karg, Margarete M, Lu, Yuancheng Ryan, Refaian, Nasrin, Cameron, James, Hoffmann, Emma, Hoppe, Cindy, Shirahama, Shintaro, Shah, Madhura, Krasniqi, Drenushe, Krishnan, Anitha, Shrestha, Maleeka, Guo, Yinjie, Cermak, Jennifer M, Walthier, Michel, Broniowska, Kasia, Rosenzweig-Lipson, Sharon, Gregory-Ksander, Meredith, Sinclair, David A, Ksander, Bruce R

“…Glaucoma, a chronic neurodegenerative disease, is a leading cause of age-related blindness worldwide and characterized by the progressive loss of retinal…”
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Effect of androgen deficiency on the human meibomian gland and ocular surface by KRENZER, Kathleen L, DANA, M. Reza, ULLMAN, M. David, CERMAK, Jennifer M, TOLLS, Dorothy B, EVANS, James E, SULLIVAN, David A

“…The purpose of this study was to determine whether the chronic use of antiandrogen medications leads to meibomian gland dysfunction, altered lipid profiles in…”
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CA125- and tumor-specific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients by Gordon, Alan N, Schultes, Birgit C, Gallion, Holly, Edwards, Robert, Whiteside, Theresa L, Cermak, Jennifer M, Nicodemus, Christopher F

“…Objective. To evaluate immune responses and clinical outcomes for combined oregovomab and chemotherapy treatment of patients with recurrent ovarian cancer…”
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Are women with Sjögren's syndrome androgen-deficient? by SULLIVAN, David A, BELANGER, Alain, CERMAK, Jennifer M, BERUBE, René, PAPAS, Athena S, SULLIVAN, Rose M, YAMAGAMI, Hiroko, REZA DANA, M, LABRIE, Fernand

“…We hypothesize that androgen deficiency is a critical etiologic factor in the pathogenesis of aqueous-deficient and evaporative dry eye in Sjögren's syndrome…”
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Is Complete Androgen Insensitivity Syndrome Associated with Alterations in the Meibomian Gland and Ocular Surface? by Cermak, Jennifer M, Krenzer, Kathleen L, Sullivan, Rose M, Dana, M Reza, Sullivan, David A

“…PURPOSE.This study's purpose was to determine whether complete androgen insensitivity syndrome (CAIS) is associated with alterations in the meibomian gland and…”
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Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus by Holmes, Gregory L, Yang, Yili, Liu, Zhao, Cermak, Jennifer M, Sarkisian, Matthew R, Stafstrom, Carl E, Neill, John C, Blusztajn, Jan K

“…Prenatal choline supplementation can protect rats against cognitive deficits induced by status epilepticus induced by the cholinergic agent pilocarpine [J…”
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Protective Effects of Prenatal Choline Supplementation on Seizure-Induced Memory Impairment by Yang, Yili, Liu, Zhao, Cermak, Jennifer M, Tandon, Pushpa, Sarkisian, Matthew R, Stafstrom, Carl E, Neill, John C, Blusztajn, Jan K, Holmes, Gregory L

“…Choline is an essential nutrient for rats and humans, and its availability during fetal development has long-lasting cognitive effects (Blusztajn, 1998). We…”
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Complete androgen insensitivity syndrome: effect on human meibomian gland secretions by Sullivan, Benjamin D, Evans, James E, Cermak, Jennifer M, Krenzer, Kathleen L, Dana, M Reza, Sullivan, David A

“…To determine whether androgen receptors affect the fatty acid profiles of neutral and polar lipids in human meibomian gland secretions. Meibomian gland…”
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Prenatal availability of choline alters the development of acetylcholinesterase in the rat hippocampus by Cermak, J M, Blusztajn, J K, Meck, W H, Williams, C L, Fitzgerald, C M, Rosene, D L, Loy, R

“…Choline (Ch) supplementation during embryonic days (ED) 12-17 enhances spatial and temporal memory in adult and aged rats, whereas prenatal Ch deficiency…”
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Androgens and Dry Eye in Sjögren's Syndromea by SULLIVAN, DAVID A., WICKHAM, L. ALEXANDRA, ROCHA, EDUARDO M., KRENZER, KATHLEEN L., SULLIVAN, BENJAMIN D., STEAGALL, REBECCA, CERMAK, JENNIFER M., DANA, M. REZA, ULLMAN, M. DAVID, SATO, ELCIO H., GAO, JIANPING, ROCHA, FLAVIO J., ONO, MASAFUMI, SILVEIRA, LILIA A., LAMBERT, ROSS WILLIAM, KELLEHER, ROBIN S., TOLLS, DOROTHY BAZZINOTTI, TODA, IKUKO

“…Sjögren's syndrome is an extremely complex and currently incurable autoimmune disorder, which occurs primarily in females, and is associated with lacrimal…”
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Developmental periods of choline sensitivity provide an ontogenetic mechanism for regulating memory capacity and age-related dementia by Meck, Warren H, Williams, Christina L, Cermak, Jennifer Marie, Blusztajn, Jan Krzysztof

“…In order to determine brain and behavioral sensitivity of nutrients that may serve as inductive signals during early development, we altered choline…”
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Abstract 981: SRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-kB/STAT3 complex to its promoter in malignant lymphoid cells by Scuto, Anna A. G., Kirschbaum, Mark, Buettner, Ralf, Cermak, Jennifer M., Atadja, Peter, Jove, Richard

“…Abstract SIRT1 is an NAD+-dependent class III histone deacetylase, which is not affected directly by HDAC inhibitors (HDACi). It remains controversial whether…”
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Novel SIRT1 Agonists, SRT501 and SRT2183, Induce Expression of DNA Repair Genes and Apoptosis of Ph− Acute Lymphoblastic Leukemia Cells Alone and in Combination with the HDAC Inhibitor LBH589 by Scuto, Anna, Kirschbaum, Mark, Cermak, Jennifer M, Atadja, Peter, Jove, Richard

“…Abstract 3083 Poster Board III-20 Histone Deacetylase Inhibitors (HDACi) such as LBH589, which inhibit the zinc containing catalytic domain of HDAC of classes…”
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Androgen Influence on the Meibomian Gland by Sullivan, David A, Sullivan, Benjamin D, Ullman, M. David, Rocha, Eduardo M, Krenzer, Kathleen L, Cermak, Jennifer M, Toda, Ikuko, Doane, Marshall G, Evans, James E, Wickham, L. Alexandra

“…The hypothesis in the study was that androgens control meibomian gland function, regulate the quality and/or quantity of lipids produced by this tissue, and…”
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Androgens and Dry Eye in Sjögren's Syndrome by SULLIVAN, DAVID A., WICKHAM, L. ALEXANDRA, ROCHA, EDUARDO M., KRENZER, KATHLEEN L., SULLIVAN, BENJAMIN D., STEAGALL, REBECCA, CERMAK, JENNIFER M., DANA, M. REZA, ULLMAN, M. DAVID, SATO, ELCIO H., GAO, JIANPING, ROCHA, FLAVIO J., ONO, MASAFUMI, SILVEIRA, LILIA A., LAMBERT, ROSS WILLIAM, KELLEHER, ROBIN S., TOLLS, DOROTHY BAZZINOTTI, TODA, IKUKO

“…Sjögren's syndrome is an extremely complex and currently incurable autoimmune disorder, which occurs primarily in females, and is associated with lacrimal…”
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Are women with Sjögren's syndrome androgen-deficient? by David A Sullivan, Alain Bélanger, Jennifer M Cermak, René BérubÃ, Athena S Papas, Rose M Sullivan, Hiroko Yamagami, M Reza Dana, Fernand Labrie

“…OBJECTIVE: We hypothesize that androgen deficiency is a critical etiologic factor in the pathogenesis of aqueous-deficient and evaporative dry eye in…”
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Effect of Androgen Deficiency on the Human Meibomian Gland and Ocular Surface1 by Krenzer, Kathleen L., Reza Dana, M., Ullman, M. David, Cermak, Jennifer M., Tolls, Dorothy B., Evans, James E., Sullivan, David A.

“…The purpose of this study was to determine whether the chronic use of antiandrogen medications leads to meibomian gland dysfunction, altered lipid profiles in…”
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Effect of Androgen Deficiency on the Human Meibomian Gland and Ocular Surface 1 by Krenzer, Kathleen L., Reza Dana, M., Ullman, M. David, Cermak, Jennifer M., Tolls, Dorothy B., Evans, James E., Sullivan, David A.

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