Search Results - "Cerimele, Benito J."

Pharmacokinetics and Safety of Duloxetine, a Dual-Serotonin and Norepinephrine Reuptake Inhibitor by Sharma, Amarnath, Goldberg, Mark J., Cerimele, Benito J.

“…The pharmacokinetics and safety of duloxetine were evaluated in a single‐blind, placebo‐controlled, escalating multiple‐dose study in 12 healthy male subjects…”
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Symmetrical crossover designs for bilateral pharmacokinetic drug interactions by VANDENHENDE, F, CERIMELE, B. J

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Why rate of absorption inferences in single dose bioequivalence studies are often inappropriate by BASSON, R. P, GHOSH, A, CERIMELE, B. J, DESANTE, K. A, HOWEY, D. C

“…Peak drug concentration (Cmax) measures the extremity of drug exposure and is a secondary indicator of the extent of absorption after area under the…”
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Effects of renal dysfunction on the pharmacokinetics of loracarbef by Therasse, D G, Farlow, D S, Davidson, R L, Quadracci, L J, Hatcher, B L, Cerimele, B J, DeSante, K A

“…Loracarbef, the first carbacephem antibiotic to undergo clinical development, is excreted primarily unchanged in the urine (> 90%). Data analyzed from subjects…”
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Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine by Ring, B J, Catlow, J, Lindsay, T J, Gillespie, T, Roskos, L K, Cerimele, B J, Swanson, S P, Hamman, M A, Wrighton, S A

“…The formation kinetics of 2-hydroxymethyl olanzapine (2-OH olanzapine), 4'-N-oxide olanzapine (N-O olanzapine) and 4'-N-desmethyl olanzapine (NdM olanzapine)…”
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The effect of sertraline on the pharmacokinetics of desipramine and imipramine by Kurtz, Darcie L., Bergstrom, Richard F., Goldberg, Mark J., Cerimele, Benito J.

“…Objective To examine the pharmacokinetic interaction between the selective serotonin reuptake inhibitor sertraline and the tricyclic antidepressants…”
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Pharmacokinetics and Safety of Duloxetine, a Dual-Serotonin and Norepinephrine Reuptake Inhibitor by Sharma, Amarnath, Goldberg, Mark J, Cerimele, Benito J

“…The pharmacokinetics and safety of duloxetine were evaluated in a single-blind, placebo-controlled, escalating multiple-dose study in 12 healthy male subjects…”
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Assessment of the potential for a pharmacokinetic interaction between fluoxetine and terfenadine by Bergstrom, Richard F., Goldberg, Mark J., Cerimele, Benito J., Hatcher, Barbara L.

“…Objective To assess whether fluoxetine and its metabolite, norfluoxetine, are inhibitors of the metabolism of CYP3A substrates. Background Because inhibition…”
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Olanzapine: Interaction Study with Imipramine by Callaghan, John T., Cerimele, Benito J., Kassahun, Kelem J., Nyhart Jr, Eldon H., Hoyes-Beehler, Pamela J., Kondraske, George V.

“…Olanzapine is an “atypical” antipsychotic agent with a high affinity for serotonin 5HT2A/C, 5HT3, 5HT6, and dopamine D1, D2, D3, D4 receptors. Depressed…”
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Pharmacokinetics of dirithromycin by Sides, G D, Cerimele, B J, Black, H R, Busch, U, DeSante, K A

“…Dirithromycin is a new member of the macrolide class of antibiotics and has been developed for oral administration. Dirithromycin is a 14-membered lactone ring…”
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Lack of Effect of Olanzapine on the Pharmacokinetics of a Single Aminophylline Dose in Healthy Men by Macias, William L., Bergstrom, Richard E, Cerimele, Benito J., Kassahun, Kelem, Tatum, David E., Callaghan, John T.

“…Study Objective. To test whether olanzapine, an atypical antipsychotic, is an inhibitor of cytochrome P450 (CYP) 1A2 activity, we conducted a drug interaction…”
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Tmax : an unconfounded metric for rate of absorption in single dose bioequivalence studies by BASSON, R. P, CERIMELE, B. J, DESANTE, K. A, HOWEY, D. C

“…While peak drug concentration (Cmax) is recognized to be contaminated by the extent of absorption, it has long served as the indicator of change in absorption…”
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Long-term arrhythmia monitoring in healthy, adult males by Bowsher, Dennis J., Cerimele, Benito J., Reid, Philip R.

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Recent graduates' and current dental students' evaluation of their prosthodontic curriculum by Haug, S P, Brown, D T, Goodacre, C J, Cerimele, B J

“…This survey of recent graduates and third- and fourth-year dental students at Indiana University School of Dentistry determined whether the prosthodontic…”
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Effect of zatosetron on ipecac-induced emesis in dogs and healthy men by Schwartz, S M, Goldberg, M J, Gidda, J S, Cerimele, B J

“…Serotonin receptor (5-HT3) antagonists provide effective antiemetic therapy in cancer patients receiving emetogenic chemotherapy, such as cisplatin. Animal…”
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Conversion of cefamandole nafate to cefamandole sodium by Indelicato, J M, Wilham, W L, Cerimele, B J

“…The rate of hydrolysis of the formyl moiety of cefamandole nafate was determined as a function of pH, temperature, and concentration of added sodium carbonate…”
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Combined effects of fenmetozole and ethanol by Griffis, L C, Bright, T P, Cerimele, B J, Forney, R B

“…Eight male subjects took none or 200 mg fenmetozole 1 hr before drinking a beverage containing none or 50 ml/70 kg ethanol. Tests designed to measure mental…”
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