Search Results - "Ceriani, Laura"
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The glycocalyx affects the mechanotransductive perception of the topographical microenvironment
Published in Journal of nanobiotechnology (19-09-2022)“…Abstract The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction, but many details of mechanotransductive signal…”
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In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models
Published in Neoplasia (New York, N.Y.) (01-01-2017)“…Abstract The fibroblast growth factor receptor (FGFR) pathway has been implicated both as an escape mechanism from anti-angiogenic therapy and as a driver…”
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MO502: Use of Lithium, Valproate and the Risk of Acute or Chronic Kidney Disease: An Observational Study From Routine Care Data
Published in Nephrology, dialysis, transplantation (03-05-2022)“…Abstract BACKGROUND AND AIMS Lithium is an established treatment for bipolar disorder and treatment-resistant depression. Despite awareness of potential kidney…”
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Quality of laboratory biomarker monitoring during treatment with lithium in patients with bipolar disorder
Published in Bipolar disorders (01-09-2023)“…Clinical guidelines recommend monitoring of creatinine and lithium throughout treatment with lithium. We here assessed the extent to which this occurs in…”
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Quantification of trabectedin in human plasma: Validation of a high-performance liquid chromatography–mass spectrometry method and its application in a clinical pharmacokinetic study
Published in Journal of pharmaceutical and biomedical analysis (01-07-2014)“…•Trabectedin was determined in human plasma by LC–MS/MS.•The method was developed and validated in a small amount of human plasma.•Extraction procedure based…”
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In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models12
Published in Neoplasia (New York, N.Y.) (15-12-2016)“…The fibroblast growth factor receptor (FGFR) pathway has been implicated both as an escape mechanism from anti-angiogenic therapy and as a driver oncogene in…”
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HPLC-MS/MS method for quantitative determination of the novel dual inhibitor of FGF and VEGF receptors E-3810 in tumor tissues from xenograft mice and human biopsies
Published in Journal of mass spectrometry. (01-01-2014)“…We developed and validated a high‐performance liquid chromatography–tandem mass spectrometry analytical method to measure E‐3810, a novel dual inhibitor of…”
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Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden
Published in JAMA network open (2023)“…Among patients with bipolar disorder, discordant findings have been published on the nephrotoxic effects of lithium therapy. To quantify absolute and relative…”
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Abstract 2670: Exploring the in vitro and in vivo activity of lucitanib in FGFR1-amplified lung cancer models
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract Lucitanib (S80881, formerly E-3810) is a novel tyrosine kinase inhibitor that selectively inhibits vascular endothelial growth factor (VEGF) receptors…”
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HPLC-MS/MS method to measure trabectedin in tumors: preliminary PK study in a mesothelioma xenograft model
Published in Bioanalysis (01-01-2015)“…Trabectedin is an anticancer agent registered for the second-line treatment of soft tissue sarcoma and ovarian cancer. No preclinical data are available on its…”
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