Search Results - "Ceresoli, Giovanni"

Stereotactic body radiation therapy for pleural mesothelioma: Which goal, which patients: Comment to “Clinical outcomes of stereotactic body radiation therapy for malignant pleural mesothelioma” by Shin et al by Ceresoli, Giovanni L., Ghirardelli, Paolo, Vavassori, Vittorio

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Tumour Treating Fields for mesothelioma – Authors' reply by Ceresoli, Giovanni L, Gianoncelli, Letizia, Grosso, Federica

“…Patients had incidental diagnosis of malignant pleural mesothelioma and were not part of a screening programme; the majority of them were enrolled in…”
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Tumour Treating Fields in combination with pemetrexed and cisplatin or carboplatin as first-line treatment for unresectable malignant pleural mesothelioma (STELLAR): a multicentre, single-arm phase 2 trial by Ceresoli, Giovanni L, Aerts, Joachim G, Dziadziuszko, Rafal, Ramlau, Rodryg, Cedres, Susana, van Meerbeeck, Jan P, Mencoboni, Manlio, Planchard, David, Chella, Antonio, Crinò, Lucio, Krzakowski, Maciej, Rüssel, Jörn, Maconi, Antonio, Gianoncelli, Letizia, Grosso, Federica

“…Tumour Treating Fields (TTFields) are a regional, antimitotic treatment for solid tumours, which is based on the delivery of low-intensity alternating electric…”
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A reply to “managing oligoprogressive malignant pleural mesothelioma with stereotactic body radiation therapy” by Ceresoli, Giovanni L., Ghirardelli, Paolo, Franceschini, Davide, Scorsetti, Marta, Vavassori, Vittorio

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Nintedanib in combination with pemetrexed and cisplatin for chemotherapy-naive patients with advanced malignant pleural mesothelioma (LUME-Meso): a double-blind, randomised, placebo-controlled phase 3 trial by Scagliotti, Giorgio V, Gaafar, Rabab, Nowak, Anna K, Nakano, Takashi, van Meerbeeck, Jan, Popat, Sanjay, Vogelzang, Nicholas J, Grosso, Federica, Aboelhassan, Rasha, Jakopovic, Marko, Ceresoli, Giovanni L, Taylor, Paul, Orlandi, Francisco, Fennell, Dean A, Novello, Silvia, Scherpereel, Arnaud, Kuribayashi, Kozo, Cedres, Susana, Sørensen, Jens Benn, Pavlakis, Nick, Reck, Martin, Velema, Derek, von Wangenheim, Ute, Kim, Miyoung, Barrueco, José, Tsao, Anne S

“…Nintedanib targets VEGF receptors 1–3, PDGF receptors α and β, FGF receptors 1–3, and Src and Abl kinases, which are all implicated in malignant pleural…”
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Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial by Kindler, Hedy L, Novello, Silvia, Bearz, Alessandra, Ceresoli, Giovanni L, Aerts, Joachim G J V, Spicer, James, Taylor, Paul, Nackaerts, Kristiaan, Greystoke, Alastair, Jennens, Ross, Calabrò, Luana, Burgers, Jacobus A, Santoro, Armando, Cedrés, Susana, Serwatowski, Piotr, Ponce, Santiago, Van Meerbeeck, Jan P, Nowak, Anna K, Blumenschein, Jr, George, Siegel, Jonathan M, Kasten, Linda, Köchert, Karl, Walter, Annette O, Childs, Barrett H, Elbi, Cem, Hassan, Raffit, Fennell, Dean A

“…Few treatment options exist for second-line treatment of malignant pleural mesothelioma. We aimed to assess the antibody-drug conjugate anetumab ravtansine…”
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Epidermal Growth Factor Receptor Gene and Protein and Gefitinib Sensitivity in Non–Small-Cell Lung Cancer by Cappuzzo, Federico, Hirsch, Fred R., Rossi, Elisa, Bartolini, Stefania, Ceresoli, Giovanni L., Bemis, Lynne, Haney, Jerry, Witta, Samir, Danenberg, Kathleen, Domenichini, Irene, Ludovini, Vienna, Magrini, Elisabetta, Gregorc, Vanesa, Doglioni, Claudio, Sidoni, Angelo, Tonato, Maurizio, Franklin, Wilbur A., Crino, Lucio, Bunn, Paul A., Varella-Garcia, Marileila

“…Background: Gefitinib is a selective inhibitor of the epidermal growth factor (EGFR) tyrosine kinase, which is overexpressed in many cancers, including…”
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Phase II Study of Pemetrexed Plus Carboplatin in Malignant Pleural Mesothelioma by CERESOLI, Giovanni L, ZUCALI, Paolo A, MARANGOLO, Maurizio, SOTO PARRA, Hector J, SANTORO, Armando, FAVARETTO, Adolfo G, GROSSI, Francesco, BIDOLI, Paolo, DEL CONTE, Guido, CERIBELLI, Anna, BEARZ, Alessandra, MORENGHI, Emanuela, CAVINA, Raffaele

“…This multicenter, phase II clinical study was conducted to evaluate the activity of the combination of pemetrexed and carboplatin in patients with malignant…”
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Salvage radiotherapy for oligo-progressive malignant pleural mesothelioma by Ghirardelli, Paolo, Franceschini, Davide, D’Aveni, Alessandro, Dominici, Luca, Ravasio, Andrea, Marzo, Marco, Villa, Elisa, Di Noia, Vincenzo, Scorsetti, Marta, Vavassori, Vittorio, Ceresoli, Giovanni L.

“…•No standard therapy is available for progressing malignant pleural mesothelioma (MPM).•Oligo-progression may occur in selected MPM patients.•In…”
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Retreatment with pemetrexed-based chemotherapy in patients with malignant pleural mesothelioma by Ceresoli, Giovanni L, Zucali, Paolo A, De Vincenzo, Fabio, Gianoncelli, Letizia, Simonelli, Matteo, Lorenzi, Elena, Ripa, Cristina, Giordano, Laura, Santoro, Armando

“…Abstract The role of second-line therapy in patients with malignant pleural mesothelioma (MPM) progressing after first-line pemetrexed-based chemotherapy (PBC)…”
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Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations by Mannarino, Laura, Mirimao, Federica, Panini, Nicolò, Paracchini, Lara, Marchini, Sergio, Beltrame, Luca, Amodeo, Rosy, Grosso, Federica, Libener, Roberta, De Simone, Irene, Ceresoli, Giovanni L., Zucali, Paolo A., Lupi, Monica, D’Incalci, Maurizio

“…Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in malignant pleural mesothelioma (MPM) patients, the mechanisms…”
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Heterogeneity of treatment effect on patients’ long-term outcome according to pathological response type in neoadjuvant RCTs for breast cancer. by Pala, Laura, Sala, Isabella, Pagan, Eleonora, De Pas, Tommaso, Zattarin, Emma, Catania, Chiara, Cocorocchio, Emilia, Rossi, Giovanna, Laszlo, Daniele, Ceresoli, Giovanni, Canzian, Jacopo, Valenzi, Elena, Bagnardi, Vincenzo, Conforti, Fabio

“…To provide evidence explaining the poor association between pCR and patients’ long-term outcome at trial-level in neoadjuvant RCTs for breast cancer (BC), we…”
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Phase II Study of Asparagine-Glycine-Arginine–Human Tumor Necrosis Factor α, a Selective Vascular Targeting Agent, in Previously Treated Patients With Malignant Pleural Mesothelioma by GREGORC, Vanesa, ZUCALI, Paolo A, SPREAFICO, Anna, VIGANO, Maria Grazia, FONTANA, Floriana, DE BRAUD, Filippo G, BAJETTA, Emilio, CALIGARIS-CAPPIO, Federico, BRUZZI, Paolo, LAMBIASE, Antonio, BORDIGNON, Claudio, SANTORO, Armando, CERESOLI, Giovanni L, CITTERIO, Giovanni, DE PAS, Tommaso M, ZILEMBO, Nicoletta, DE VINCENZO, Fabio, SIMONELLI, Matteo, ROSSONI, Gilda

“…NGR-hTNF consists of human tumor necrosis factor alpha (hTNF-alpha) fused to the tumor-homing peptide asparagine-glycine-arginine (NGR) able to selectively…”
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Increased HER2 Gene Copy Number Is Associated With Response to Gefitinib Therapy in Epidermal Growth Factor Receptor–Positive Non–Small-Cell Lung Cancer Patients by CAPPUZZO, Federico, VARELLA-GARCIA, Marileila, FRANKLIN, Wilbur A, CRINO, Lucid, GAZDAR, Adi F, BUNN, Paul A, HIRSCH, Fred R, SHIGEMATSU, Hisayuki, DOMENICHINI, Irene, BARTOLINI, Stefania, CERESOLI, Giovanni L, ROSSI, Elisa, LUDOVINI, Vienna, GREGORC, Vanesa, TOSCHI, Luca

“…In non-small-cell lung cancer (NSCLC), response to tyrosine kinase inhibitors (TKIs) is significantly associated with the presence of increased copy number…”
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Early Response Evaluation in Malignant Pleural Mesothelioma by Positron Emission Tomography With [18F]Fluorodeoxyglucose by CERESOLI, Giovanni L, CHITI, Arturo, ZUCALI, Paolo A, RODARI, Marcello, LUTMAN, Romano F, SALAMINA, Silvia, INCARBONE, Matteo, ALLOISIO, Marco, SANTORO, Armando

“…Response evaluation with conventional criteria based on computed tomography (CT) is particularly challenging in malignant pleural mesothelioma (MPM) due to its…”
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Thymidylate Synthase and Excision Repair Cross-Complementing Group-1 as Predictors of Responsiveness in Mesothelioma Patients Treated with Pemetrexed/Carboplatin by ANDREA ZUCALI, Paolo, GIOVANNETTI, Elisa, BRUZZONE, Andrea, THUNNISSEN, Erik, TUNESI, Gianni, GIORDANO, Laura, RONCALLI, Massimo, PETERS, Godefridus J, SANTORO, Armando, DESTRO, Annarita, MENCOBONI, Manlio, LUCA CERESOLI, Giovanni, GIANONCELLI, Letizia, LORENZI, Elena, DE VINCENZO, Fabio, SIMONELLI, Matteo, PERRINO, Matteo

“…The pemetrexed/platinum agent combination represents the standard of care in first-line treatment for malignant pleural mesothelioma (MPM). However, there are…”
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Gemcitabine and vinorelbine in pemetrexed‐pretreated patients with malignant pleural mesothelioma by Zucali, Paolo A., Ceresoli, Giovanni L., Garassino, Isabella, De Vincenzo, Fabio, Cavina, Raffaele, Campagnoli, Elisabetta, Cappuzzo, Federico, Salamina, Silvia, Soto Parra, Hector J., Santoro, Armando

“…BACKGROUND Pemetrexed‐cisplatin chemotherapy is the standard of care in the first‐line treatment of unresectable malignant pleural mesothelioma (MPM)…”
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Significance of Neutrophil-to-lymphocyte Ratio in Western Advanced EGFR-mutated Non-small Cell Lung Cancer Receiving a Targeted Therapy by Meriggi, Fausto, Codignola, Claudio, Beretta, Giordano D., Ceresoli, Giovanni L., Caprioli, Alberto, Scartozzi, Mario, Fraccon, Anna P., Prochilo, Tiziana, Ogliosi, Chiara, Zaniboni, Alberto

“…Purpose Lung cancer is one of the leading causes of cancer-related death worldwide and, although targeted therapy with tyrosine kinase inhibitors has…”
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Primary pulmonary meningioma Report of a case and review of the literature by INCARBONE, Matteo, LUCA CERESOLI, Giovanni, DI TOMMASO, Luca, CAPPUZZO, Federico, INZIRILLO, Francesco, INFANTE, Maurizio, ALLOISIO, Marco

“…Primary pulmonary meningioma (PPM) is a rare disease and usually presents as a solitary pulmonary nodule (SPN). These lesions are mostly benign, but malignant…”
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Molecular Alterations in Spontaneous Sputum of Cancer-Free Heavy Smokers: Results from a Large Screening Program by BARYSHNIKOVA, Ekaterina, DESTRO, Annarita, RAVASI, Gianni, RONCALLI, Massimo, VALENTINO INFANTE, Maurizio, CAVUTO, Silvio, CARIBONI, Umberto, ALLOISIO, Marco, LUCA CERESOLI, Giovanni, LUTMAN, Romano, BRAMBILLA, Giorgio, CHIESA, Giuseppe

“…Purpose: The high mortality rate for lung cancer is likely to be reduced by the development of a panel of sensitive biological markers able to identify…”
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