Search Results - "Cercós, Pilar"

Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease by Naranjo, José R, Zhang, Hongyu, Villar, Diego, González, Paz, Dopazo, Xose M, Morón-Oset, Javier, Higueras, Elena, Oliveros, Juan C, Arrabal, María D, Prieto, Angela, Cercós, Pilar, González, Teresa, De la Cruz, Alicia, Casado-Vela, Juan, Rábano, Alberto, Valenzuela, Carmen, Gutierrez-Rodriguez, Marta, Li, Jia-Yi, Mellström, Britt

“…Deregulated protein and Ca2+ homeostasis underlie synaptic dysfunction and neurodegeneration in Huntington disease (HD); however, the factors that disrupt…”
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IQM-PC332, a Novel DREAM Ligand with Antinociceptive Effect on Peripheral Nerve Injury-Induced Pain by Socuéllamos, Paula G, Olivos-Oré, Luis A, Barahona, María Victoria, Cercós, Pilar, Pérez Pascual, Marta, Arribas-Blázquez, Marina, Naranjo, José Ramón, Valenzuela, Carmen, Gutiérrez-Rodríguez, Marta, Artalejo, Antonio R

“…Neuropathic pain is a form of chronic pain arising from damage of the neural cells that sense, transmit or process sensory information. Given its growing…”
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Pharmacological Approaches for the Modulation of the Potassium Channel KV4.x and KChIPs by Cercós, Pilar, Peraza, Diego A., Benito-Bueno, Angela de, Socuéllamos, Paula G., Aziz-Nignan, Abdoul, Arrechaga-Estévez, Dariel, Beato, Escarle, Peña-Acevedo, Emilio, Albert, Armando, González-Vera, Juan A., Rodríguez, Yoel, Martín-Martínez, Mercedes, Valenzuela, Carmen, Gutiérrez-Rodríguez, Marta

“…Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group…”
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Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment by Lopez-Hurtado, Alejandro, Peraza, Diego A., Cercos, Pilar, Lagartera, Laura, Gonzalez, Paz, Dopazo, Xose M., Herranz, Rosario, Gonzalez, Teresa, Martin-Martinez, Mercedes, Mellström, Britt, Naranjo, Jose R., Valenzuela, Carmen, Gutierrez-Rodriguez, Marta

“…DREAM, a neuronal calcium sensor protein, has multiple cellular roles including the regulation of Ca 2+ and protein homeostasis. We recently showed that…”
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Modulation of KV4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2 by de Benito-Bueno, Angela, Socuellamos, Paula G., Merinero, Yaiza G., Cercos, Pilar, Izquierdo, Carolina, Daniel-Mozo, Miguel, Marín-Olivero, Irene, Perez-Lara, Angel, Gonzalez-Vera, Juan A., Orte, Angel, Albert, Armando, Martin-Martinez, Mercedes, Gutierrez-Rodriguez, Marta, Valenzuela, Carmen

“…The transient outward potassium current (Itof) is generated by the activation of KV4 channels assembled with KChIP2 and other accessory subunits (DPP6 and…”
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Identification of IQM-266, a Novel DREAM Ligand That Modulates KV4 Currents by Peraza, Diego A., Cercós, Pilar, Miaja, Pablo, Merinero, Yaiza G., Lagartera, Laura, Socuéllamos, Paula G., Izquierdo García, Carolina, Sánchez, Sara A., López-Hurtado, Alejandro, Martín-Martínez, Mercedes, Olivos-Oré, Luis A., Naranjo, José R., Artalejo, Antonio R., Gutiérrez-Rodríguez, Marta, Valenzuela, Carmen

“…DREAM/KChIP3/calsenilin is a neuronal calcium sensor with multiple functions, including the regulation of A-type outward potassium currents (IA). This effect…”
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Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease by Naranjo, José R, Zhang, Hongyu, Villar, Diego, González, Paz, Dopazo, Xose M, Morón-Oset, Javier, Higueras, Elena, Oliveros, Juan C, Arrabal, María D, Prieto, Angela, Cercós, Pilar, González, Teresa, De la Cruz, Alicia, Casado-Vela, Juan, Rábano, Alberto, Valenzuela, Carmen, Gutierrez-Rodriguez, Marta, Li, Jia-Yi, Mellström, Britt

“…Deregulated protein and Ca^sup 2+^ homeostasis underlie synaptic dysfunction and neurodegeneration in Huntington disease (HD); however, the factors that…”
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Pharmacological Approaches for the Modulation of the Potassium Channel K V 4.x and KChIPs by Cercós, Pilar, Peraza, Diego A, Benito-Bueno, Angela de, Socuéllamos, Paula G, Aziz-Nignan, Abdoul, Arrechaga-Estévez, Dariel, Beato, Escarle, Peña-Acevedo, Emilio, Albert, Armando, González-Vera, Juan A, Rodríguez, Yoel, Martín-Martínez, Mercedes, Valenzuela, Carmen, Gutiérrez-Rodríguez, Marta

“…Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group…”
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Identification of IQM-266, a Novel DREAM Ligand That Modulates K V 4 Currents by Peraza, Diego A, Cercós, Pilar, Miaja, Pablo, Merinero, Yaiza G, Lagartera, Laura, Socuéllamos, Paula G, Izquierdo García, Carolina, Sánchez, Sara A, López-Hurtado, Alejandro, Martín-Martínez, Mercedes, Olivos-Oré, Luis A, Naranjo, José R, Artalejo, Antonio R, Gutiérrez-Rodríguez, Marta, Valenzuela, Carmen

“…Downstream Regulatory Element Antagonist Modulator (DREAM)/KChIP3/calsenilin is a neuronal calcium sensor (NCS) with multiple functions, including the…”
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Effects of Cl888 on Kv4.3, Kv4.3/Kchip2C and Kv4.3/KChiP3 Channels by Prieto, Angela, Cercos, Pilar, de la Cruz, Alicia, Gonzalez, Teresa, Gutierrez-Rodriguez, Marta, Naranjo, Jose-Ramon, Valenzuela, Carmen

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Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease by Naranjo, Jose R, Zhang, Hongyu, Villar, Diego, Gonzalez, Paz, Dopazo, Xose M, Moron-Oset, Javier, Higueras, Elena, Oliveros, Juan C, Arrabal, Maria D, Prieto, Angela, Cercos, Pilar, Gonzalez, Teresa, De la Cruz, Alicia, Casado-Vela, Juan, Rabano, Alberto, Valenzuela, Carmen, Gutierrez-Rodriguez, Marta, Li, Jia-Yi, Mellstrom, Britt

“…Deregulated protein and [Ca.sup.2+] homeostasis underlie synaptic dysfunction and neurodegeneration in Huntington disease (HD); however, the factors that…”
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