Search Results - "Cerabona, Donna"
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Specific cell ablation in Drosophila using the toxic viral protein M2(H37A)
Published in Fly (Austin, Tex.) (01-10-2010)“…The expression of toxic viral proteins for the purpose of eliminating distinct populations of cells, while leaving the rest of an organism unaffected, is a…”
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2
Leukemia and chromosomal instability in aged Fancc−/− mice
Published in Experimental hematology (01-05-2016)“…Fanconi anemia (FA) is an inherited disorder of genomic instability associated with high risk of myelodysplasia and acute myeloid leukemia (AML). Young mice…”
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3
Cdkn3 Knockout Mice Develop Hematopoietic Malignancies
Published in Blood (02-12-2016)“…Cyclin dependent kinase inhibitor 3 (CDKN3) is a dual-specificity cell cycle regulatory phosphatase. In interphase, CDKN3 prevents premature G1/S transition by…”
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4
Genomic Instability in Fanconi Anemia Results from a Combination of Chromosome Mis-Segregation in Mitosis and Unresolved Interphase DNA Damage
Published in Blood (06-12-2014)“…Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure, multiple congenital anomalies, and genomic instability resulting in…”
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Impaired Spindle Assembly Checkpoint In Vivo Promotes MDS/AML in a Novel Mouse Model of Fanconi Anemia
Published in Blood (03-12-2015)“…The Fanconi anemia (FA/BRCA) signaling network prevents bone marrow failure and cancer by protecting genomic integrity. Biallelic germline mutations within…”
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FANCA safeguards interphase and mitosis during hematopoiesis in vivo
Published in Experimental hematology (01-12-2015)“…The Fanconi anemia (FA/BRCA) signaling network controls multiple genome-housekeeping checkpoints, from interphase DNA repair to mitosis. The in vivo role of…”
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Correction for Sierra Potchanant et al., "INPP5E Preserves Genomic Stability through Regulation of Mitosis"
Published in Molecular and cellular biology (15-10-2017)Get full text
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8
Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk
Published in The Journal of clinical investigation (01-01-2013)“…Neurofibromatosis type 1 (NF1) predisposes individuals to the development of juvenile myelomonocytic leukemia (JMML), a fatal myeloproliferative disease (MPD)…”
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9
INPP5E Preserves Genomic Stability through Regulation of Mitosis
Published in Molecular and cellular biology (01-03-2017)“…The partially understood phosphoinositide signaling cascade regulates multiple aspects of cellular metabolism. Previous studies revealed that INPP5E, the…”
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10
Fanconi anemia pathway safeguards interphase and mitosis in vivo
Published in Experimental hematology (01-09-2015)Get full text
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11
FANCA Controls Mitotic Phosphosignaling Networks To Ensure Genome Stability During Cell Division
Published in Blood (15-11-2013)“…Fanconi anemia (FA) is a heterogenous genome instability syndrome with a high risk of cancer. The FA proteins are essential for interphase DNA damage repair…”
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12
Normal Hematopoiesis and Neurofibromin-Deficient Myeloproliferative Disease Require Erk
Published in Blood (16-11-2012)“…Abstract ▪704▪This icon denotes a clinically relevant abstract Neurofibromatosis type 1 predisposes individuals to the development of juvenile myelomonocytic…”
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13
TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis
Published in BoneKEy reports (08-07-2015)“…Mechanistic understanding of the preferential homing of circulating tumor cells to bone and their perturbation on bone metabolism within the tumor-bone…”
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TGF[beta]-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis
Published in BoneKEy reports (01-07-2015)“…Mechanistic understanding of the preferential homing of circulating tumor cells to bone and their perturbation on bone metabolism within the tumor-bone…”
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