Search Results - "Cerù, Maria Paola"

Targeting PPARalpha in Alzheimer's Disease by D'Orio, Barbara, Fracassi, Anna, Ceru, Maria Paola, Moreno, Sandra

“…The molecular mechanisms underlying Alzheimer's disease (AD) are yet to be fully elucidated. The so-called "amyloid cascade hypothesis" has long been the…”
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Emerging Roles of Peroxisome Proliferator-Activated Receptors (PPARs) in the Regulation of Neural Stem Cells Proliferation and Differentiation by Cimini, AnnaMaria, Cerù, Maria Paola

“…The molecular mechanisms controlling the specification of neural cell fates have been the focus of intense research in recent years. Neural precursor cells…”
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Corrigendum to “PPARs in Human Neuroepithelial Tumors: PPAR Ligands as Anticancer Therapies for the Most Common Human Neuroepithelial Tumors” by Cerù, Maria Paola, D'Angelo, Barbara, Galzio, Renato, Benedetti, Elisabetta, Cimini, AnnaMaria

“…The article titled “PPARs in Human Neuroepithelial Tumors: PPAR Ligands as Anticancer Therapies for the Most Common Human Neuroepithelial Tumors” [1] was found…”
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In search for novel strategies towards neuroprotection and neuroregeneration: is PPARα a promising therapeutic target? by Moreno, Sandra, Cerù, Maria Paola

“…[...]the roles played by PPARs in the brain are incompletely understood, especially in relation to the isotype-specific mechanisms of action. [...]the…”
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Neuroprotective properties of peroxisome proliferator-activated receptor alpha (PPARα) and its lipid ligands by Fidaleo, Marco, Fanelli, Francesca, Ceru, Maria Paola, Moreno, Sandra

“…Signalling lipids are known to control a wide array of cellular processes, including cell proliferation, apoptosis, migration, and energy metabolism. Fatty…”
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PPARs in Human Neuroepithelial Tumors: PPAR Ligands as Anticancer Therapies for the Most Common Human Neuroepithelial Tumors by Benedetti, Elisabetta, Galzio, Renato, D'Angelo, Barbara, Cerù, Maria Paola, Cimini, Annamaria

“…Neuroepithelial tumors represent a heterogeneous class of human tumors including benignant and malignant tumors. The incidence of central nervous system…”
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Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer’s Disease by Moreno, Sandra, Cerù, Maria Paola, Bernardi, Cinzia, Cecconi, Francesco, Sepe, Sara, Fracassi, Anna, Fanelli, Francesca, Porcellotti, Sara, Cimini, AnnaMaria

“…Alzheimer’s disease (AD) is the most common form of dementia, characterized by progressive neurodegeneration. Pathogenetic mechanisms, triggered by β-amyloid…”
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Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes by Cimini, AnnaMaria, Moreno, Sandra, D'Amelio, Marcello, Cristiano, Loredana, D'Angelo, Barbara, Falone, Stefano, Benedetti, Elisabetta, Carrara, Paolo, Fanelli, Francesca, Cecconi, Francesco, Amicarelli, Fernanda, Cerù, Maria Paola

“…The central role of peroxisomes in reactive oxygen species and lipid metabolism and their importance in brain functioning are well established. The aim of this…”
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An overview of the effect of linoleic and conjugated‐linoleic acids on the growth of several human tumor cell lines by Maggiora, Marina, Bologna, Mauro, Cerù, Maria Paola, Possati, Laura, Angelucci, Angelo, Cimini, Anna, Miglietta, Antonella, Bozzo, Francesca, Margiotta, Chiara, Muzio, Guiliana, Canuto, Rosa Angela

“…Both n‐6 and n‐3 polyunsaturated fatty acids are dietary fats important for cell function, being involved in several physiologic and pathologic processes, such…”
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p73 and p63 regulate the expression of fibroblast growth factor receptor 3 by Sayan, A. Emre, D’Angelo, Barbara, Sayan, Berna S., Tucci, Paola, Cimini, AnnaMaria, Cerù, Maria Paola, Knight, Richard A., Melino, Gerry

“…p53, p63 and p73 make a family of transcription factors that play a vital role in development and cancer. All p53 family members have more than one promoter…”
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PPARγ‐dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF) by Cimini, AnnaMaria, Cristiano, Loredana, Colafarina, Sabrina, Benedetti, Elisabetta, Di Loreto, Silvia, Festuccia, Claudio, Amicarelli, Fernanda, Canuto, Rosa Angela, Cerù, Maria Paola

“…Conjugated linoleic acid (CLA) has been shown to exert beneficial effects against carcinogenesis, atherosclerosis and diabetes. It has been demonstrated that…”
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Neuroendocrine transdifferentiation induced by VPA is mediated by PPARγ activation and confers resistance to antiblastic therapy in prostate carcinoma by Angelucci, Adriano, Muzi, Paola, Cristiano, Loredana, Millimaggi, Danilo, Cimini, AnnaMaria, Dolo, Vincenza, Miano, Roberto, Vicentini, Carlo, Cerù, Maria Paola, Bologna, Mauro

“…BACKGROUND Prostate cancer (PCa) is the most commonly diagnosed cancer in men in the Western Countries. When prostatectomy fails to eradicate the primary…”
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Regional and Ultrastructural Immunolocalization of Copper-Zinc Superoxide Dismutase in Rat Central Nervous System by Moreno, Sandra, Nardacci, Roberta, Ceru, Maria Paola

“…We examined the distribution of copper-zinc superoxide dismutase (CuZn-SOD) in adult rat central nervous system by light and electron microscopic…”
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Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury by Amicarelli, Fernanda, Colafarina, Sabrina, Cattani, Franca, Cimini, Annamaria, Di Ilio, Carmine, Ceru, Maria Paola, Miranda, Michele

“…Methylglyoxal is a reactive dicarbonyl compound endogenously produced mainly from glycolytic intermediates. Recent research indicates that methylglyoxal is a…”
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Oxidative Stress during the Progression of [beta]-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease by Porcellotti, Sara, Fanelli, Francesca, Fracassi, Anna, Sepe, Sara, Cecconi, Francesco, Bernardi, Cinzia, Cimini, AnnaMaria, Cerù, Maria Paola, Moreno, Sandra

“…Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive neurodegeneration. Pathogenetic mechanisms, triggered by β-amyloid…”
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Liver peroxisomes in newborns from clofibrate-treated rats. II. A biochemical study of the recovery period by Sartori, C, Stefanini, S, Cimini, A, Di Giulio, A, Cerù, M P

“…The fatty-acyl-CoA beta-oxidation (FAO) and catalase activities, as well as membrane fluidity of liver peroxisomes of newborns from normal and…”
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Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma by Angelucci, Adriano, Muzi, Paola, Cristiano, Loredana, Millimaggi, Danilo, Cimini, AnnaMaria, Dolo, Vincenza, Miano, Roberto, Vicentini, Carlo, Cerù, Maria Paola, Bologna, Mauro

“…Prostate cancer (PCa) is the most commonly diagnosed cancer in men in the Western Countries. When prostatectomy fails to eradicate the primary tumor, PCa is…”
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Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea by Bonfigli, Antonella, Zarivi, Osvaldo, Colafarina, Sabrina, Cimini, Anna Maria, Ragnelli, Anna Maria, Aimola, Pierpaolo, Natali, Pier Giorgio, Cerù, Maria Paola, Amicarelli, Fernanda, Miranda, Michele

“…Melanocytes and neuroblasts share the property of transforming L‐tyrosine through two distinct metabolic pathways leading to melanogenesis and catecholamine…”
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PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF) by Cimini, AnnaMaria, Cristiano, Loredana, Colafarina, Sabrina, Benedetti, Elisabetta, Di Loreto, Silvia, Festuccia, Claudio, Amicarelli, Fernanda, Canuto, Rosa Angela, Cerù, Maria Paola

“…Conjugated linoleic acid (CLA) has been shown to exert beneficial effects against carcinogenesis, atherosclerosis and diabetes. It has been demonstrated that…”
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Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease by Fanelli, Francesca, Sepe, Sara, D'Amelio, Marcello, Bernardi, Cinzia, Cristiano, Loredana, Cimini, AnnaMaria, Cecconi, Francesco, Ceru', Maria Paola, Moreno, Sandra

“…Alzheimer's Disease (AD) is a progressive neurodegenerative disease, especially affecting the hippocampus. Impairment of cognitive and memory functions is…”
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