Search Results - "Cepko, C. L."

Vertebrate neural cell-fate determination: Lessons from the retina by Livesey, F. J, Cepko, C. L

“…Postmitotic neurons are produced from a pool of cycling progenitors in an orderly fashion during development. Studies of cell-fate determination in the…”
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The Noncoding RNA Taurine Upregulated Gene 1 Is Required for Differentiation of the Murine Retina by Young, T.L., Matsuda, T., Cepko, C.L.

“…Background: With the advent of genome-wide analyses, it is becoming evident that a large number of noncoding RNAs (ncRNAs) are expressed in vertebrates…”
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Retinal progenitor cells can produce restricted subsets of horizontal cells by Rompani, S.B, Cepko, C.L

“…Retinal progenitor cells have been shown to be multipotent throughout development. Similarly, many other structures of the developing central nervous system…”
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Characterization of Mice with Targeted Deletion of Glycine Receptor Alpha 2 by Young-Pearse, T. L., Ivic, L., Kriegstein, A. R., Cepko, C. L.

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An Analysis of the Gene Expression Program of Mammalian Neural Progenitor Cells by Livesey, F. J., Young, T. L., Cepko, C. L.

“…A diverse range of neural cell types is generated from a pool of dividing stem and progenitor cells in an orderly manner during development. Little is known of…”
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Retinopathy and attenuated circadian entrainment in Crx -deficient mice by Furukawa, Takahisa, Cepko, Constance L, Morrow, Eric M, Li, Tiansen, Davis, Fred C

“…Crx, an Otx-like homeobox gene, is expressed specifically in the photoreceptors of the retina and the pinealocytes of the pineal gland. Crx has been proposed…”
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p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina by Dyer, M A, Cepko, C L

“…A precise balance between proliferation and differentiation must be maintained during retinal development to obtain the correct proportion of each of the seven…”
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Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx by Livesey, F.J., Furukawa, T., Steffen, M.A., Church, G.M., Cepko, C.L.

“…Background: Terminal differentiation of many cell types is controlled and maintained by tissue or cell-specific transcription factors. Little is known,…”
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Cell Fate Determination in the Vertebrate Retina by Cepko, Constance L., Austin, Christopher P., Yang, Xianjie, Alexiades, Macrene, Ezzeddine, Diala

“…In the vertebrate central nervous system, the retina has been a useful model for studies of cell fate determination. Recent results from studies conducted in…”
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Clonally Related Cortical Cells Show Several Migration Patterns by Walsh, C., Cepko, C. L.

“…The mammalian cerebral cortex is organized into columns of cells with common functional properties. During embryogenesis, cortical neurons are formed deep,…”
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Regulation of Chamber-Specific Gene Expression in the Developing Heart by Irx4 by Bao, Zheng-Zheng, Bruneau, Benoit G., Seidman, J. G., Seidman, Christine E., Cepko, Constance L.

“…The vertebrate heart consists of two types of chambers, the atria and the ventricles, which differ in their contractile and electrophysiological properties…”
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Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis by Daiger, Stephen P, Sohocki, Melanie M, Bowne, Sara J, Sullivan, Lori S, Blackshaw, Seth, Cepko, Constance L, Payne, Annette M, Bhattacharya, Shomi S, Khaliq, Shagufta, Qasim Mehdi, S, Birch, David G, Harrison, Wilbur R, Elder, Frederick F.B, Heckenlively, John R

“…Leber congenital amaurosis (LCA, MIM 204000) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the…”
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Development of the pattern of photoreceptors in the chick retina by Bruhn, SL, Cepko, CL

“…The various classes of photoreceptor cells found in vertebrate retinae are organized in specific patterns, which are important for visual function. It is not…”
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All Brn3 genes can promote retinal ganglion cell differentiation in the chick by Liu, W, Khare, S L, Liang, X, Peters, M A, Liu, X, Cepko, C L, Xiang, M

“…Targeted gene disruption studies in the mouse have demonstrated crucial roles for the Brn3 POU domain transcription factor genes, Brn3a, Brn3b, Brn3c (now…”
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Widespread Dispersion of Neuronal Clones Across Functional Regions of the Cerebral Cortex by Walsh, Christopher, Cepko, Constance L.

“…The cerebral cortex of the mammalian brain has expanded rapidly during the course of evolution and acquired structurally distinguishable areas devoted to…”
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Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo by FEKETE, D. M, CEPKO, C. L

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Two homeobox genes define the domain of EphA3 expression in the developing chick retina by Schulte, D, Cepko, C L

“…Graded expression of the Eph receptor EphA3 in the retina and its two ligands, ephrin A2 and ephrin A5 in the optic tectum, the primary target of retinal…”
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A Recombinant Retrovirus Encoding Alkaline Phosphatase Confirms Clonal Boundary Assignment in Lineage Analysis of Murine Retina by Fields-Berry, Shawn C., Halliday, Andrea L., Cepko, Constance L.

“…Recombinant retroviruses encoding the histochemically detectable enzyme β-galactosidase have been used to investigate lineage in the vertebrate nervous system…”
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Cardiomyopathy in Irx4-Deficient Mice Is Preceded by Abnormal Ventricular Gene Expression by Bruneau, Benoit G., Bao, Zheng-Zheng, Fatkin, Diane, Xavier-Neto, Jose, Georgakopoulos, Dimitrios, Maguire, Colin T., Berul, Charles I., Kass, David A., Kuroski-de Bold, Mercedes L., de Bold, Adolfo J., Conner, David A., Rosenthal, Nadia, Cepko, Constance L., Seidman, Christine E., Seidman, J. G.

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Immortalization of neural cells via retrovirus-mediated oncogene transduction by CEPKO, C. L

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