Search Results - "Centeno, B."

Potentially inappropriate medications in older adults living with HIV by López‐Centeno, B, Badenes‐Olmedo, C, Mataix‐Sanjuan, A, Bellón, JM, Pérez‐Latorre, L, López, JC, Benedí, J, Khoo, S, Marzolini, C, Calvo‐Alcántara, MJ, Berenguer, J

“…Objectives We assessed the prevalence of potentially inappropriate medication (PIM) among older (≥ 65 years) people living with HIV (O‐PLWH) in the region of…”
Get full text

miR-675 Mediates Downregulation of Twist1 and Rb in AFP-Secreting Hepatocellular Carcinoma by Hernandez, J. M., Elahi, A., Clark, C. W., Wang, J., Humphries, L. A., Centeno, B., Bloom, G., Fuchs, B. C., Yeatman, T., Shibata, D.

“…Background Alpha-fetoprotein (AFP)-secreting hepatocellular carcinomas (HCC) represent a genetically distinct subset of tumors often associated with a worse…”
Get full text

Modulation of the Fibrillogenesis Inhibition Properties of Two Transthyretin Ligands by Halogenation by Cotrina, Ellen Y, Pinto, Marta, Bosch, Lluís, Vilà, Marta, Blasi, Daniel, Quintana, Jordi, Centeno, Nuria B, Arsequell, Gemma, Planas, Antoni, Valencia, Gregorio

“…The amyloidogenic protein transthyretin (TTR) is thought to aggregate into amyloid fibrils by tetramer dissociation which can be inhibited by a number of small…”
Get full text

Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors by Mairal, Teresa, Nieto, Joan, Pinto, Marta, Almeida, Maria Rosário, Gales, Luis, Ballesteros, Alfredo, Barluenga, José, Pérez, Juan J, Vázquez, Jesús T, Centeno, Nuria B, Saraiva, Maria Joao, Damas, Ana M, Planas, Antoni, Arsequell, Gemma, Valencia, Gregorio

“…The thyroid hormone and retinol transporter protein known as transthyretin (TTR) is in the origin of one of the 20 or so known amyloid diseases. TTR self…”
Get full text

Synchronous rectal adenocarcinoma and splenic marginal zone lymphoma by Srikumar, T, Markow, M, Centeno, B, Hoffe, S, Tao, J, Fernandez, H, Strosberg, J, Shibata, D

“…Synchronous cancers of different primary origin are rare. Here, we describe the case of a patient with concomitant diagnoses of rectal adenocarcinoma and…”
Get full text

Design, Synthesis, and Structure−Activity Relationships of 1-,3-,8-, and 9-Substituted-9-deazaxanthines at the Human A2B Adenosine Receptor by Carotti, Angelo, Cadavid, Maria Isabel, Centeno, Nuria B, Esteve, Cristina, Loza, Maria Isabel, Martinez, Ana, Nieto, Rosa, Raviña, Enrique, Sanz, Ferran, Segarra, Victor, Sotelo, Eddy, Stefanachi, Angela, Vidal, Bernat

“…Over two hundred 1-, 3-, 8-, and 9-substituted-9-deazaxanthines were prepared and evaluated for their binding affinity at the recombinant human adenosine…”
Get full text

Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approach by Cotrina, Ellen Y., Blasi, Daniel, Vilà, Marta, Planas, Antoni, Abad-Zapatero, Cele, Centeno, Nuria B., Quintana, Jordi, Arsequell, Gemma

“…Ligand efficiency indices (LEIs) were applied prospectively for the first time to select a set of biphenyl derivatives as transthyretin inhibitors by virtual…”
Get full text

Detection and tumor staging of malignancy in cystic, intraductal, and solid tumors of the pancreas by EUS by Brandwein, Steven L., Farrell, James J., Centeno, Barbara A., Brugge, William R.

“…Background: EUS can provide detailed imaging of pancreatic malignancies and direct fine needle aspiration (FNA) of pancreatic masses. The ability of EUS to…”
Get full text

New Serotonin 5-HT2A, 5-HT2B, and 5-HT2C Receptor Antagonists:  Synthesis, Pharmacology, 3D-QSAR, and Molecular Modeling of (Aminoalkyl)benzo and Heterocycloalkanones by Brea, José, Rodrigo, Jordi, Carrieri, Antonio, Sanz, Ferran, Cadavid, M. Isabel, Enguix, María J, Villazón, María, Mengod, Guadalupe, Caro, Yolanda, Masaguer, Christian F, Raviña, Enrique, Centeno, Nuria B, Carotti, Angelo, Loza, M. Isabel

“…A series of 52 conformationally constrained butyrophenones have been synthesized and pharmacologically tested as antagonists at 5-HT2A, 5-HT2B, and 5-HT2C…”
Get full text

4CPS-217 Hepatitis b treatment: towards effectiveness and adherence by Centeno, B Lopez, Castro, V Alonso, Martín, A Gil, Casasempere, I Martín, Oyarzábal, A Aranguren, Alcántara, MJCalvo

“…BackgroundAlthough hepatitis B (HB) drugs have strong antiviral activity, they cannot eradicate the virus, so they must be administered for long periods of…”
Get full text

4CPS-105 Prescribed antineoplastic agents in paediatric patients by Alonso Castro, V, López Centeno, B, Martín Casasempere, I, Alioto, D, Gil Martín, A, Segura Bedmar, M, Aranguren Oyarzábal, A, Calvo Alcántara, MJ

“…BackgroundMany medicines prescribed for children have not been formally studied. Therefore, most of them are not labelled to be used in paediatric patients…”
Get full text

Comparative modelling of protein structure and its impact on microbial cell factories by Centeno, Nuria B, Planas-Iglesias, Joan, Oliva, Baldomero

“…Comparative modeling is becoming an increasingly helpful technique in microbial cell factories as the knowledge of the three-dimensional structure of a protein…”
Get full text

3D-QSAR methods on the basis of ligand-receptor complexes. Application of COMBINE and GRID/GOLPE methodologies to a series of CYP1A2 ligands by Lozano, J J, Pastor, M, Cruciani, G, Gaedt, K, Centeno, N B, Gago, F, Sanz, F

“…Many heterocyclic amines (HCA) present in cooked food exert a genotoxic activity when they are metabolised (N-oxidated) by the human cytochrome P450 1A2…”
Get full text

1ISG-021 A comprehensive regional strategy addressing guidance on safe handling of hazardous drugs by Alioto, D, Cañamares Orbis, I, Segura Bedmar, M, Tourne Izquierdo, BM, Lopez Gomez, FJ, Lopez Centeno, B, Alonso Castro, V, Gil Martin, A, Martin Casasempere, I, Aranguren Oyarzabal, A, Calvo Alcantara, MJ

“…BackgroundOccupational exposure to hazardous drugs (HDs) is a mounting public health concern. Nevertheless, currently there are not harmonised standards for…”
Get full text

Identification of tree species from the Peruvian tropical amazon “Selva Central” forests according to wood anatomy by Ferreira, Cassiana A., Inga, Janet G., Vidal, Osir D., Goytendia, Walter E., Moya, Sthefany M., Centeno, Thonny B., Vélez, Andrés, Gamarra, Daniel, Tomazello-Filho, Mario

“…The “Selva Central” of Peru is characterized by its forest species richness that produces quality wood for countless uses. Therefore, it is necessary to…”
Get full text

Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E  -tocotrienol by Husain, K., Centeno, B. A., Chen, D.-T., Fulp, W. J., Perez, M., Zhang Lee, G., Luetteke, N., Hingorani, S. R., Sebti, S. M., Malafa, M. P.

Get full text

2SPD-027 Centralised purchasing as a strategic line for the rationalisation of pharmaceutical expenditure in a regional health service by Castro, V Alonso, Centeno, B Lopez, Palacios, JL Pinar, Casasempere, I Martin, Martin, A Gil, Oyarzabal, A Aranguren, Alcantara, MJCalvo

“…BackgroundCentralised drug purchasing in a Regional Health Service enhances efficiency in drugs’ procurement and ensures that all hospitals in charge of the…”
Get full text

Pyridazine derivatives. Part 27: A joint theoretical and experimental approach to the synthesis of 6-phenyl-4,5-disubstituted-3(2 H)-pyridazinones by Sotelo, Eddy, Centeno, Nuria B, Rodrigo, Jordi, Raviña, Enrique

“…A theoretical study of the structures of a series of 5-substituted-6-phenyl-3(2 H)-pyridazinones has been carried out using quantum-mechanical calculations…”
Get full text

Cyst fluid analysis in the differential diagnosis of pancreatic cysts: a new approach to the preoperative assessment of pancreatic cystic lesions by Lewandrowski, K, Lee, J, Southern, J, Centeno, B, Warshaw, A

“…Pancreatic cysts include pseudocysts, serous tumors, and mucinous tumors, some of which are malignant. The clinical and radiologic features of these lesions…”
Get full text

CP-094 Communication among centralised health service and hospital pharmacy: What can we improve? by Centeno, B Lopez, Castro, V Alonso, Martín, A Gil, Oyarzábal, A Aranguren, Alcántara, MJ Calvo, Martos, E Cruz

“…BackgroundThe register and assessment of queries received in a centralised health service (CHS) from hospital pharmacists and other professionals allow…”
Get full text