Search Results - "Cendali, Francesca I."
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Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC)
Published in Metabolites (26-10-2022)“…Exercise intolerance is a major manifestation of post-acute sequelae of severe acute respiratory syndrome coronavirus infection (PASC, or "long-COVID")…”
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Metabolic correlates to critical speed in murine models of sickle cell disease
Published in Frontiers in physiology (13-03-2023)“…Exercise intolerance is a common clinical manifestation in patients with sickle cell disease (SCD), though the mechanisms are incompletely understood. Here we…”
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Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19
Published in Cells (Basel, Switzerland) (02-09-2021)“…The Corona Virus Disease 2019 (COVID-19) pandemic represents an ongoing worldwide challenge. The present large study sought to understand independent and…”
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Peritoneal Infusion of Oxygen Microbubbles Alters the Metabolomic Profile of the Lung and Spleen in Acute Hypoxic Exposure
Published in Bioengineering (Basel) (27-07-2024)“…Administration of oxygen microbubbles (OMBs) has been shown to increase oxygen and decrease carbon dioxide in systemic circulation, as well as reduce lung…”
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Multiomics Signatures of Coagulopathy in a Polytrauma Swine Model Contrasted with Severe Multisystem Injured Patients
Published in Journal of proteome research (05-04-2024)“…Trauma-induced coagulopathy (TIC) is a leading contributor to preventable mortality in severely injured patients. Understanding the molecular drivers of TIC is…”
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Omics Signatures of Tissue Injury and Hemorrhagic Shock in Swine
Published in Annals of surgery (01-12-2023)“…Advanced mass spectrometry methods were leveraged to analyze both proteomics and metabolomics signatures in plasma upon controlled tissue injury (TI) and…”
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Primaquine-5,6-Orthoquinone Is Directly Hemolytic to Older G6PD Deficient RBCs in a Humanized Mouse Model
Published in The Journal of pharmacology and experimental therapeutics (18-09-2024)“…Primaquine and Tafenoquine are the only approved drugs that can achieve a radical cure for malaria but are contraindicated in patients who are deficient in…”
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The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells
Published in Molecular and cellular endocrinology (01-06-2022)“…Luteinizing hormone (LH) stimulates testosterone production from Leydig cells. Both LH and testosterone play important roles in spermatogenesis and male…”
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Increased exercise tolerance in humanized G6PD deficient mice
Published in Blood advances (08-11-2024)“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency affects 500 million people globally, impacting red blood cell (RBC) antioxidant pathways and increasing…”
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Obesity and PKD: Mechanistic Studies Using the Pkd1RC/RC Model: TH-PO406
Published in Journal of the American Society of Nephrology (01-11-2023)Get full text
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Acute Hypoxic Exercise In Healthy Subjects Increases Red Blood Cell Acylcarnitines And Glycolysis: 1673
Published in Medicine and science in sports and exercise (01-09-2023)Get full text
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