Search Results - "Cenci, Giovanni"

Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements by Cacchione, Stefano, Cenci, Giovanni, Raffa, Grazia Daniela

“…The maintenance of chromosome ends in Drosophila is an exceptional phenomenon because it relies on the transposition of specialized retrotransposons rather…”
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Editorial: The Genetic and Epigenetic Bases of Cellular Response to Ionizing Radiation by Seong, Ki Moon, Cenci, Giovanni

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Reduced Environmental Dose Rates Are Responsible for the Increased Susceptibility to Radiation-Induced DNA Damage in Larval Neuroblasts of Drosophila Grown inside the LNGS Underground Laboratory by Porrazzo, Antonella, Esposito, Giuseppe, Grifoni, Daniela, Cenci, Giovanni, Morciano, Patrizia, Tabocchini, Maria Antonella

“…A large amount of evidence from radiobiology studies carried out in Deep Underground Laboratories support the view that environmental radiation may trigger…”
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The Organization of the Golgi Structures during Drosophila Male Meiosis Requires the Citrate Lyase ATPCL by Morciano, Patrizia, Di Giorgio, Maria Laura, Tullo, Liliana, Cenci, Giovanni

“…During spermatogenesis, the Golgi apparatus serves important roles including the formation of the acrosome, which is a sperm-specific organelle essential for…”
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Drosophila cell cycle under arrest: Uncapped telomeres plead guilty by Cenci, Giovanni

“…Telomeres are specialized structures that protect chromosome ends from degradation and fusion events. In most organisms, telomeres consist of short, repetitive…”
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An inherited TBX3 alteration in a prenatal case of ulnar-mammary syndrome: Clinical assessment and functional characterization in Drosophila melanogaster by Irene, Bottillo, Andrea, D'Alessandro, Pia, Ciccone Maria, Gianluca, Cestra, Gianluca, Di Giacomo, Evelina, Silvestri, Marco, Castori, Francesco, Brancati, Andrea, Lenzi, Alessandro, Paiardini, Silvia, Majore, Giovanni, Cenci, Paola, Grammatico

“…Ulnar mammary syndrome (UMS) results from heterozygous variants in the TBX3 gene and impacts limb, tooth, hair, apocrine gland, and genitalia development. The…”
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Co-amplification of CBX3 with EGFR or RAC1 in human cancers corroborated by a conserved genetic interaction among the genes by Bosso, Giuseppe, Cipressa, Francesca, Tullo, Liliana, Cenci, Giovanni

“…Chromobox Protein 3 (CBX3) overexpression is a common event occurring in cancer, promotes cancer cell proliferation and represents a poor prognosis marker in a…”
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Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma by Pomella, Silvia, Porrazzo, Antonella, Cassandri, Matteo, Camero, Simona, Codenotti, Silvia, Milazzo, Luisa, Vulcano, Francesca, Barillari, Giovanni, Cenci, Giovanni, Marchese, Cinzia, Fanzani, Alessandro, Megiorni, Francesca, Rota, Rossella, Marampon, Francesco

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and adolescence that includes FP-RMS, harboring the fusion oncoprotein PAX3/7-FOXO1…”
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Food-Associated Lactobacillus plantarum and Yeasts Inhibit the Genotoxic Effect of 4-Nitroquinoline-1-Oxide by Prete, Roberta, Tofalo, Rosanna, Federici, Ermanno, Ciarrocchi, Aurora, Cenci, Giovanni, Corsetti, Aldo

“…Lactic acid bacteria and yeasts, representing the prevailing microbiota associated with different foods generally consumed without any cooking, were identified…”
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A role for Separase in telomere protection by Cipressa, Francesca, Morciano, Patrizia, Bosso, Giuseppe, Mannini, Linda, Galati, Alessandra, Daniela Raffa, Grazia, Cacchione, Stefano, Musio, Antonio, Cenci, Giovanni

“…Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity and are assembled independently of the…”
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Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development by Maccallini, Paolo, Bavasso, Francesca, Scatolini, Livia, Bucciarelli, Elisabetta, Noviello, Gemma, Lisi, Veronica, Palumbo, Valeria, D'Angeli, Simone, Cacchione, Stefano, Cenci, Giovanni, Ciapponi, Laura, Wakefield, James G, Gatti, Maurizio, Raffa, Grazia Daniela

“…Trimethylguanosine synthase 1 (TGS1) is a conserved enzyme that mediates formation of the trimethylguanosine cap on several RNAs, including snRNAs and…”
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AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance by Burla, Romina, Carcuro, Mariateresa, Raffa, Grazia D, Galati, Alessandra, Raimondo, Domenico, Rizzo, Angela, La Torre, Mattia, Micheli, Emanuela, Ciapponi, Laura, Cenci, Giovanni, Cundari, Enrico, Musio, Antonio, Biroccio, Annamaria, Cacchione, Stefano, Gatti, Maurizio, Saggio, Isabella

“…Telomeres are nucleoprotein complexes that protect the ends of linear chromosomes from incomplete replication, degradation and detection as DNA breaks…”
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Two-phase olive mill waste composting: Community dynamics and functional role of the resident microbiota by Federici, Ermanno, Pepi, Milva, Esposito, Alessandro, Scargetta, Silvia, Fidati, Laura, Gasperini, Simone, Cenci, Giovanni, Altieri, Roberto

“…► High quality compost was produced from a two-phase olive mill waste. ► Size and diversity of the resident microbiota were related to the different composting…”
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The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo by Vaccaro, Sara, Rossetti, Alessandra, Porrazzo, Antonella, Camero, Simona, Cassandri, Matteo, Pomella, Silvia, Tomaciello, Miriam, Macioce, Giampiero, Pedini, Francesca, Barillari, Giovanni, Marchese, Cinzia, Rota, Rossella, Cenci, Giovanni, Tombolini, Mario, Newman, Robert A., Yang, Peiying, Codenotti, Silvia, Fanzani, Alessandro, Megiorni, Francesca, Festuccia, Claudio, Minniti, Giuseppe, Gravina, Giovanni Luca, Vulcano, Francesca, Milazzo, Luisa, Marampon, Francesco

“…Treatment of rhabdomyosarcoma (RMS), the most common a soft tissue sarcoma in childhood, provides intensive multimodal therapy, with radiotherapy (RT) playing…”
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Depletion of ATP-Citrate Lyase (ATPCL) Affects Chromosome Integrity Without Altering Histone Acetylation in Drosophila Mitotic Cells by Morciano, Patrizia, Di Giorgio, Maria Laura, Porrazzo, Antonella, Licursi, Valerio, Negri, Rodolfo, Rong, Yikang, Cenci, Giovanni

“…The Citrate Lyase (ACL) is the main cytosolic enzyme that converts the citrate exported from mitochondria by the SLC25A1 carrier in Acetyl Coenzyme A…”
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The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres by Cenci, Giovanni, Ciapponi, Laura, Marzullo, Marta, Raffa, Grazia D, Morciano, Patrizia, Raimondo, Domenico, Burla, Romina, Saggio, Isabella, Gatti, Maurizio

“…Drosophila telomeres are sequence-independent structures that are maintained by transposition to chromosome ends of three specialized retroelements (HeT-A,…”
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Reduced RNA turnover as a driver of cellular senescence by Mullani, Nowsheen, Porozhan, Yevheniia, Mangelinck, Adèle, Rachez, Christophe, Costallat, Mickael, Batsché, Eric, Goodhardt, Michele, Cenci, Giovanni, Mann, Carl, Muchardt, Christian

“…Accumulation of senescent cells is an important contributor to chronic inflammation upon aging. The inflammatory phenotype of senescent cells was previously…”
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In Vitro Inhibition of 4-Nitroquinoline-1-Oxide Genotoxicity by Probiotic Lactobacillus rhamnosus IMC501 by Bocci, Alessandro, Sebastiani, Bartolomeo, Trotta, Francesca, Federici, Ermanno, Cenci, Giovanni

“…Inhibition of 4-nitroquinoline-1-oxide (4-NQO) genotoxicity by a probiotic strain of Lactobacillus rhamnosus (IMC501) was assessed by the prokaryotic…”
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Identification of the Telomere elongation Mutation in Drosophila by Reddy, Hemakumar M, Randall, Thomas A, Cipressa, Francesca, Porrazzo, Antonella, Cenci, Giovanni, Frydrychova, Radmila Capkova, Mason, James M

“…Telomeres in , which have inspired a large part of Sergio Pimpinelli work, are similar to those of other eukaryotes in terms of their function. Yet, their…”
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Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection by Raffa, Grazia D, Siriaco, Giorgia, Cugusi, Simona, Ciapponi, Laura, Cenci, Giovanni, Wojcik, Edward, Gatti, Maurizio

“…Several proteins have been identified that protect Drosophila telomeres from fusion events. They include UbcD1, HP1, HOAP, the components of the…”
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