Search Results - "Cen, Zhihong"
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The Role of B Cells in Regulation of Th Cell Differentiation in Coxsackievirus B3–Induced Acute Myocarditis
Published in Inflammation (01-10-2021)“…Viral myocarditis (VMC) is the major cause of sudden death in adolescents. To date, no effective treatment has been identified for VMC. Studies have shown that…”
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The abnormal distribution of peripheral B1 cells and transition B cells in patients with idiopathic dilated cardiomyopathy: a pilot study
Published in BMC cardiovascular disorders (04-03-2022)“…The aberrant distribution of peripheral B cell subsets is associated with the pathogenesis of a variety of inflammatory and autoimmune diseases. However, the…”
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The absence of B cells disrupts splenic and myocardial Treg homeostasis in coxsackievirus B3-induced myocarditis
Published in Clinical and experimental immunology (13-05-2022)“…Although B cells are essential for humoral immunity and show noteworthy immunomodulatory activity through antibody-independent functions, the role of B cells…”
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CD4+TEM cells drive the progression from acute myocarditis to dilated cardiomyopathy in CVB3-induced BALB/c mice
Published in International immunopharmacology (25-01-2024)“…Acute viral myocarditis can progress to chronic myocarditis leading to dilated cardiomyopathy (DCM). Persistent CD4+ T-cell-mediated autoimmunity triggered by…”
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Cardiac macrophages undergo dynamic changes after coxsackievirus B3 infection and promote the progression of myocarditis
Published in Journal of medical virology (01-08-2023)“…Although most patients with acute viral myocarditis recover spontaneously, some patients progress to heart failure. Perturbations in innate immunity may…”
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IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis
Published in Virology journal (30-12-2014)“…A new subset of T helper (Th) cells, named IL-22-producing Th22 cells, was identified recently. Th22 cells have been implicated in immunity and inflammation…”
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7
CD4 + T EM cells drive the progression from acute myocarditis to dilated cardiomyopathy in CVB3-induced BALB/c mice
Published in International immunopharmacology (25-01-2024)“…Acute viral myocarditis can progress to chronic myocarditis leading to dilated cardiomyopathy (DCM). Persistent CD4 T-cell-mediated autoimmunity triggered by…”
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8
The absence of B cells disrupts splenic and myocardial Treg homeostasis in coxsackievirus B3-induced myocarditis
Published in Clinical and experimental immunology (13-05-2022)“…Although B cells are essential for humoral immunity and show noteworthy immunomodulatory activity through antibody-independent functions, the role of B cells…”
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IL-10-producing B cells involved in the pathogenesis of Coxsackie virus B3-induced acute viral myocarditis
Published in International journal of clinical and experimental pathology (2015)“…Interleukin-10 (IL-10)-producing B cells, a subset of regulatory B cells, play critical roles in autoimmune and infectious diseases. However, the role of…”
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Increased circulating interleukin 10-secreting B cells in patients with dilated cardiomyopathy
Published in International journal of clinical and experimental pathology (01-01-2015)“…Regulatory B cells (Bregs) have recently been implicated in the pathogenesis of autoimmune diseases. However, their role in the pathogenesis of dilated…”
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22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis
Published in Virology journal (2014)“…BACKGROUND: A new subset of T helper (Th) cells, named IL-22-producing Th22 cells, was identified recently. Th22 cells have been implicated in immunity and…”
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