Search Results - "Cells (Basel, Switzerland)"

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis by Doyle, Laura M, Wang, Michael Zhuo

“…The use of extracellular vesicles, specifically exosomes, as carriers of biomarkers in extracellular spaces has been well demonstrated. Despite their promising…”
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Osteoblast-Osteoclast Communication and Bone Homeostasis by Kim, Jung-Min, Lin, Chujiao, Stavre, Zheni, Greenblatt, Matthew B, Shim, Jae-Hyuck

“…Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate…”
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miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis by Condrat, Carmen Elena, Thompson, Dana Claudia, Barbu, Madalina Gabriela, Bugnar, Oana Larisa, Boboc, Andreea, Cretoiu, Dragos, Suciu, Nicolae, Cretoiu, Sanda Maria, Voinea, Silviu Cristian

“…MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of regulating mRNA through its degradation and adjusting protein levels. In…”
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Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives by Roehlen, Natascha, Crouchet, Emilie, Baumert, Thomas F

“…Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global health. Correlating with liver disease progression, fibrosis is…”
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Management of Rheumatoid Arthritis: An Overview by Radu, Andrei-Flavius, Bungau, Simona Gabriela

“…Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology, primarily affecting the joints, then extra-articular manifestations can…”
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The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges by Loh, Chin-Yap, Chai, Jian Yi, Tang, Ting Fang, Wong, Won Fen, Sethi, Gautam, Shanmugam, Muthu Kumaraswamy, Chong, Pei Pei, Looi, Chung Yeng

“…Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis where the EMT program enhances metastasis, chemoresistance and tumor…”
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Mesenchymal Stem Cells for Regenerative Medicine by Han, Yu, Li, Xuezhou, Zhang, Yanbo, Han, Yuping, Chang, Fei, Ding, Jianxun

“…In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have attracted increasing attention. MSCs are easily extracted from the bone…”
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Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis by Lin, Yen-Ju, Anzaghe, Martina, Schülke, Stefan

“…Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally. It is characterized by an inflammation of the tendon…”
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Mesenchymal Stem Cell Migration and Tissue Repair by Fu, Xiaorong, Liu, Ge, Halim, Alexander, Ju, Yang, Luo, Qing, Song, And Guanbin

“…Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and differentiate into a variety of cell types, which play key roles in…”
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High-Fat, Western-Style Diet, Systemic Inflammation, and Gut Microbiota: A Narrative Review by Malesza, Ida Judyta, Malesza, Michał, Walkowiak, Jarosław, Mussin, Nadiar, Walkowiak, Dariusz, Aringazina, Raisa, Bartkowiak-Wieczorek, Joanna, Mądry, Edyta

“…The gut microbiota is responsible for recovering energy from food, providing hosts with vitamins, and providing a barrier function against exogenous pathogens…”
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Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes by Gurunathan, Sangiliyandi, Kang, Min-Hee, Jeyaraj, Muniyandi, Qasim, Muhammad, Kim, Jin-Hoi

“…Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids, RNA, and DNA. They are derived from endocytic membranes and can…”
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Long Non-Coding RNA in the Pathogenesis of Cancers by Chi, Yujing, Wang, Di, Wang, Junpei, Yu, Weidong, Yang, Jichun

“…The incidence and mortality rate of cancer has been quickly increasing in the past decades. At present, cancer has become the leading cause of death worldwide…”
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Oxidative Stress in Human Pathology and Aging: Molecular Mechanisms and Perspectives by Hajam, Younis Ahmad, Rani, Raksha, Ganie, Shahid Yousuf, Sheikh, Tariq Ahmad, Javaid, Darakhshan, Qadri, Syed Sanober, Pramodh, Sreepoorna, Alsulimani, Ahmad, Alkhanani, Mustfa F, Harakeh, Steve, Hussain, Arif, Haque, Shafiul, Reshi, Mohd Salim

“…Reactive oxygen and nitrogen species (RONS) are generated through various endogenous and exogenous processes; however, they are neutralized by enzymatic and…”
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Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases by Harrell, Carl Randall, Jovicic, Nemanja, Djonov, Valentin, Arsenijevic, Nebojsa, Volarevic, Vladislav

“…There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression was mainly attributed to the effects of MSC-derived extracellular vesicles…”
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TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis-Updated 2019 by Dewidar, Bedair, Meyer, Christoph, Dooley, Steven, Meindl-Beinker, And Nadja

“…Liver fibrosis is an advanced liver disease condition, which could progress to cirrhosis and hepatocellular carcinoma. To date, there is no direct approved…”
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scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells by Wang, Zhengpin, Xu, Xiaojiang

“…In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both high sequence…”
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Inflammation in Parkinson's Disease: Mechanisms and Therapeutic Implications by Pajares, Marta, I Rojo, Ana, Manda, Gina, Boscá, Lisardo, Cuadrado, Antonio

“…Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized by the death of dopaminergic neurons that project from the substantia…”
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Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19 by Yadav, Rohitash, Chaudhary, Jitendra Kumar, Jain, Neeraj, Chaudhary, Pankaj Kumar, Khanra, Supriya, Dhamija, Puneet, Sharma, Ambika, Kumar, Ashish, Handu, Shailendra

“…Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been…”
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Influence of Nitrogen and Phosphorus on Microalgal Growth, Biomass, Lipid, and Fatty Acid Production: An Overview by Yaakob, Maizatul Azrina, Mohamed, Radin Maya Saphira Radin, Al-Gheethi, Adel, Aswathnarayana Gokare, Ravishankar, Ambati, Ranga Rao

“…Microalgae can be used as a source of alternative food, animal feed, biofuel, fertilizer, cosmetics, nutraceuticals and for pharmaceutical purposes. The…”
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A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping by Romano, Maria, Ruggiero, Alessia, Squeglia, Flavia, Maga, Giovanni, Berisio, Rita

“…The current coronavirus disease-2019 (COVID-19) pandemic is due to the novel coronavirus SARS-CoV-2. The scientific community has mounted a strong response by…”
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