Search Results - "Cell transplantation"

Clinical Trials With Mesenchymal Stem Cells: An Update by Squillaro, Tiziana, Peluso, Gianfranco, Galderisi, Umberto

“…In the last year, the promising features of mesenchymal stem cells (MSCs), including their regenerative properties and ability to differentiate into diverse…”
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The Pros and Cons of Mesenchymal Stem Cell-Based Therapies by Musiał-Wysocka, Aleksandra, Kot, Marta, Majka, Marcin

“…The need to search for new, alternative treatments for various diseases has prompted scientists and physicians to focus their attention on regenerative…”
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Fighting against Skin Aging: The Way from Bench to Bedside by Zhang, Shoubing, Duan, Enkui

“…As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging…”
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Microenvironment Imbalance of Spinal Cord Injury by Fan, Baoyou, Wei, Zhijian, Yao, Xue, Shi, Guidong, Cheng, Xin, Zhou, Xianhu, Zhou, Hengxing, Ning, Guangzhi, Kong, Xiaohong, Feng, Shiqing

“…Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient physiology and psychology. The microenvironment of the injured…”
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Traumatic Brain Injury: Current Treatment Strategies and Future Endeavors by Galgano, Michael, Toshkezi, Gentian, Qiu, Xuecheng, Russell, Thomas, Chin, Lawrence, Zhao, Li-Ru

“…Traumatic brain injury (TBI) presents in various forms ranging from mild alterations of consciousness to an unrelenting comatose state and death. In the most…”
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Cryopreservation: An Overview of Principles and Cell-Specific Considerations by Whaley, David, Damyar, Kimia, Witek, Rafal P., Mendoza, Alan, Alexander, Michael, Lakey, Jonathan RT

“…The origins of low-temperature tissue storage research date back to the late 1800s. Over half a century later, osmotic stress was revealed to be a main…”
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Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives by Liang, Xiaoting, Ding, Yue, Zhang, Yuelin, Tse, Hung-Fat, Lian, Qizhou

“…Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical practice as therapeutic agents for immunomodulation and ischemic…”
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Cerebral Small Vessel Disease by Li, Qian, Yang, Yang, Reis, Cesar, Tao, Tao, Li, Wanwei, Li, Xiaogang, Zhang, John H.

“…Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and…”
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Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy by Ding, Dah-Ching, Chang, Yu-Hsun, Shyu, Woei-Cherng, Lin, Shinn-Zong

“…The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure…”
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The Gut Microbiota in Multiple Sclerosis: An Overview of Clinical Trials by Schepici, Giovanni, Silvestro, Serena, Bramanti, Placido, Mazzon, Emanuela

“…Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, and degenerative disease that affects the central nervous system. A recent study showed that…”
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Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development by Ganguly, Payal, El-Jawhari, Jehan J., Giannoudis, Peter V., Burska, Agata N., Ponchel, Frederique, Jones, Elena A.

“…Aging at the cellular level is a complex process resulting from accumulation of various damages leading to functional impairment and a reduced quality of life…”
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Secondary Release of Exosomes from Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery after Stroke in Rats Treated with Exosomes Harvested from MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stromal Cells by Xin, Hongqi, Wang, Fengjie, Li, Yanfeng, Lu, Qing-E, Cheung, Wing Lee, Zhang, Yi, Zhang, Zheng Gang, Chopp, Michael

“…We previously demonstrated that multipotent mesenchymal stromal cells (MSCs) that overexpress microRNA 133b (miR-133b) significantly improve functional…”
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Repeated Mild Traumatic Brain Injury: Potential Mechanisms of Damage by Fehily, Brooke, Fitzgerald, Melinda

“…Mild traumatic brain injury (mTBI) represents a significant public healthcare concern, accounting for the majority of all head injuries. While symptoms are…”
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MicroRNA-133a and Myocardial Infarction by Xiao, Yi, Zhao, Jiling, Tuazon, Julian P., Borlongan, Cesar V., Yu, Guolong

“…Myocardial infarction (MI) is the leading cause of morbidity and mortality in the world. The infarcted heart displays typical cell death cascades characterized…”
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Significant Improvement of Acute Complete Spinal Cord Injury Patients Diagnosed by a Combined Criteria Implanted with NeuroRegen Scaffolds and Mesenchymal Stem Cells by Xiao, Zhifeng, Tang, Fengwu, Zhao, Yannan, Han, Guang, Yin, Na, Li, Xing, Chen, Bing, Han, Sufang, Jiang, Xianfeng, Yun, Chen, Zhao, Changyu, Cheng, Shixiang, Zhang, Sai, Dai, Jianwu

“…Stem cells and biomaterials transplantation hold a promising treatment for functional recovery in spinal cord injury (SCI) animal models. However, the…”
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Non-Coding RNA in Acute Ischemic Stroke: Mechanisms, Biomarkers and Therapeutic Targets by Wang, Sheng-Wen, Liu, Zhong, Shi, Zhong-Song

“…Non-coding RNAs (ncRNAs) are a class of functional RNAs that regulate gene expression in a post-transcriptional manner. NcRNAs include microRNAs, long…”
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Screening Hub Genes as Prognostic Biomarkers of Hepatocellular Carcinoma by Bioinformatics Analysis by Zhou, Zengyuan, Li, Yuzheng, Hao, Haiyue, Wang, Yuanyuan, Zhou, Zihao, Wang, Zhipeng, Chu, Xia

“…Hepatocellular carcinoma (HCC) is a widespread, common type of cancer in Asian countries, and the need for biomarker-matched molecularly targeted therapy for…”
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Exosomes from Bone Marrow Mesenchymal Stem Cells Inhibit Neuronal Apoptosis and Promote Motor Function Recovery via the Wnt/β-catenin Signaling Pathway by Li, Ci, Jiao, Guangjun, Wu, Wenliang, Wang, Hongliang, Ren, Shanwu, Zhang, Lu, Zhou, Hongming, Liu, Haichun, Chen, Yunzhen

“…Severe spinal cord injury (SCI) is caused by external mechanical injury, resulting in unrecoverable neurological injury. Recent studies have shown that…”
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The Systematic Effect of Mesenchymal Stem Cell Therapy in Critical COVID-19 Patients: A Prospective Double Controlled Trial by Adas, G, Cukurova, Z, Yasar, K Kart, Yilmaz, R, Isiksacan, N, Kasapoglu, P, Yesilbag, Z, Koyuncu, ID, Karaoz, E

“…The aim of this clinical trial was to control the cytokine storm by administering mesenchymal stem cells (MSCs) to critically-ill COVID-19 patients, to…”
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Immunoregulatory Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles on T Lymphocytes by Del Fattore, Andrea, Luciano, Rosa, Pascucci, Luisa, Goffredo, Bianca Maria, Giorda, Ezio, Scapaticci, Margherita, Fierabracci, Alessandra, Muraca, Maurizio

“…The immunomodulatory activity of mesenchymal stem cells (MSCs) is largely mediated by paracrine factors. We have recently shown that the immunosuppressive…”
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