Search Results - "Cell proliferation"

Exosomes from adipose‐derived stem cells and application to skin wound healing by An, Yang, Lin, Shuyan, Tan, Xiaojie, Zhu, Shiou, Nie, Fangfei, Zhen, Yonghuan, Gu, Luosha, Zhang, Chunlei, Wang, Baicheng, Wei, Wei, Li, Dong, Wu, Junhao

“…Skin wound healing is an intractable problem that represents an urgent clinical need. To solve this problem, a large number of studies have focused on the use…”
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Immune modulation by mesenchymal stem cells by Jiang, Wei, Xu, Jianyong

“…Mesenchymal stem cells (MSCs) can be derived from various adult tissues with multipotent and self‐renewal abilities. The characteristics of presenting no major…”
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Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF‐1α/SLC7A11 pathway by Yuan, Siyu, Wei, Can, Liu, Guofang, Zhang, Lijun, Li, Jiahao, Li, Lingling, Cai, Shiyi, Fang, Ling

“…Objectives Evidences demonstrate that sorafenib alleviates liver fibrosis via inhibiting HSC activation and ECM accumulation. The underlying mechanism remains…”
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Role of pyroptosis in cardiovascular disease by Zhaolin, Zeng, Guohua, Li, Shiyuan, Wu, Zuo, Wang

“…Cardiac function is determined by the dynamic equilibrium of various cell types and the extracellular matrix that composes the heart. Cardiovascular diseases…”
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Role of the CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting by Xu, Maosen, Wang, Yang, Xia, Ruolan, Wei, Yuquan, Wei, Xiawei

“…The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and progression of various cancers. CCL2 can activate tumour cell growth and…”
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Exosomes derived from miR‐375‐overexpressing human adipose mesenchymal stem cells promote bone regeneration by Chen, Si, Tang, Yiman, Liu, Yunsong, Zhang, Ping, Lv, Longwei, Zhang, Xiao, Jia, Lingfei, Zhou, Yongsheng

“…Objectives The present study aimed to investigate whether exosomes derived from miR‐375‐overexpressing human adipose mesenchymal stem cells (hASCs) could…”
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Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway by Zhou, Jin, Jiang, Yuan‐yuan, Chen, Huan, Wu, Yi‐chao, Zhang, Li

“…Objectives Tanshinone I (Tan‐I) is one of the vital fatsoluble monomer components, which extracted from Chinese medicinal herb Salvia miltiorrhiza Bunge. It…”
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Programmed cell death in spinal cord injury pathogenesis and therapy by Shi, Zhongju, Yuan, Shiyang, Shi, Linlin, Li, Jiahe, Ning, Guangzhi, Kong, Xiaohong, Feng, Shiqing

“…Spinal cord injury (SCI) always leads to functional deterioration due to a series of processes including cell death. In recent years, programmed cell death…”
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Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID‐19 by Xia, Qi‐Dong, Xun, Yang, Lu, Jun‐Lin, Lu, Yu‐Chao, Yang, Yuan‐Yuan, Zhou, Peng, Hu, Jia, Li, Cong, Wang, Shao‐Gang

“…Objectives Coronavirus disease 2019 (COVID‐19) is rapidly spreading worldwide. Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with…”
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Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis by Jiang, Yuhe, Zhang, Ping, Zhang, Xiao, Lv, Longwei, Zhou, Yongsheng

“…Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and microstructural degeneration. The personal and societal costs of…”
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The role of astrocytes in oxidative stress of central nervous system: A mixed blessing by Chen, Yaxing, Qin, Chen, Huang, Jianhan, Tang, Xin, Liu, Chang, Huang, Keru, Xu, Jianguo, Guo, Gang, Tong, Aiping, Zhou, Liangxue

“…Central nervous system (CNS) maintains a high level of metabolism, which leads to the generation of large amounts of free radicals, and it is also one of the…”
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Detection of SARS‐CoV‐2 in saliva and characterization of oral symptoms in COVID‐19 patients by Chen, Lili, Zhao, Jiajia, Peng, Jinfeng, Li, Xiaoshuang, Deng, Xuliang, Geng, Zhi, Shen, Zhenyu, Guo, Fengyuan, Zhang, Qianwen, Jin, Yang, Wang, Lin, Wang, Songlin

“…Objectives In order to provide a more comprehensive understanding of the effects of SARS‐CoV‐2 on oral health and possible saliva transmission, we performed…”
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The PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities by He, Xuegang, Li, Ying, Deng, Bo, Lin, Aixin, Zhang, Guangzhi, Ma, Miao, Wang, Yonggang, Yang, Yong, Kang, Xuewen

“…Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below the injured segment of the spinal cord, which significantly impacts the…”
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Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration by Zhao, Kangcheng, An, Ran, Xiang, Qian, Li, Gaocai, Wang, Kun, Song, Yu, Liao, Zhiwei, Li, Shuai, Hua, Wenbin, Feng, Xiaobo, Wu, Xinghuo, Zhang, Yukun, Das, Abhirup, Yang, Cao

“…Objective Lactate accumulation is an important factor in the intervertebral disc degeneration (IVDD). Currently, the effect and underlying mechanism of action…”
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NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration by Zhang, Guang‐Zhi, Liu, Ming‐Qiang, Chen, Hai‐Wei, Wu, Zuo‐Long, Gao, Yi‐Cheng, Ma, Zhan‐Jun, He, Xue‐Gang, Kang, Xue‐Wen

“…Intervertebral disc degeneration (IDD) is a common clinical degenerative disease of the spine. A series of factors, such as inflammation, oxidative stress and…”
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Cellular senescence and cancer: Focusing on traditional Chinese medicine and natural products by Liu, Yiman, Yang, Shenshen, Wang, Kailong, Lu, Jia, Bao, Xiaomei, Wang, Rui, Qiu, Yuling, Wang, Tao, Yu, Haiyang

“…Cancer is the principal cause of death and a dominant public health problem which seriously threatening human life. Among various ways to treat cancer,…”
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Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF‐1α‐mediated promotion of angiogenesis in a rat model of stabilized fracture by Zhang, Yuntong, Hao, Zichen, Wang, Panfeng, Xia, Yan, Wu, Jianghong, Xia, Demeng, Fang, Shuo, Xu, Shuogui

“…Objectives Exosomes, as important players in intercellular communication due to their ability to transfer certain molecules to target cells, are believed to…”
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Exosome biogenesis, secretion and function of exosomal miRNAs in skeletal muscle myogenesis by Yue, Binglin, Yang, Haiyan, Wang, Jian, Ru, Wenxiu, Wu, Jiyao, Huang, Yongzheng, Lan, Xianyong, Lei, Chuzhao, Chen, Hong

“…Exosomes are membrane‐bound extracellular vesicles that are produced in the endosomal compartment of most mammalian cell types and then released. Exosomes are…”
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D‐mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF‐2α‐dependent manner by Zhou, Xueman, Zheng, Yingcheng, Sun, Wentian, Zhang, Zhenzhen, Liu, Jiaqi, Yang, Wenke, Yuan, Wenxiu, Yi, Yating, Wang, Jun, Liu, Jin

“…Objectives Chondrocyte ferroptosis contributes to osteoarthritis (OA) progression, and D‐mannose shows therapeutic value in many inflammatory conditions. Here,…”
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TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury by Wang, Yao, Zhang, Haiyue, Chen, Qian, Jiao, Fangzhou, Shi, Chunxia, Pei, Maohua, Lv, Jian, Zhang, Hong, Wang, Luwen, Gong, Zuojiong

“…Objective Acute kidney injury (AKI) is a common complication of acute liver failure (ALF). Pyroptosis is a necrosis type related to inflammation. This study…”
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