Search Results - "Cell health and cytoskeleton"

Alterations in cancer cell mechanical properties after fluid shear stress exposure: a micropipette aspiration study by Chivukula, Venkat Keshav, Krog, Benjamin L, Nauseef, Jones T, Henry, Michael D, Vigmostad, Sarah C

“…Over 90% of cancer deaths result not from primary tumor development, but from metastatic tumors that arise after cancer cells circulate to distal sites via the…”
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New developments in C5a receptor signaling by Sarma, J Vidya, Ward, Peter A

“…Complement activation usually results in the formation of complement fragment 5a (C5a) that interacts with its two receptors, C5aR and C5L2. These receptors…”
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Structure of, and functional insight into the GLUT family of membrane transporters by Long, Wentong, Cheeseman, Chris I

“…This review examines the development of structure and function of the human GLUT proteins, gene family hSLC2A. These proteins are essential for moving the key…”
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Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress by Natarajan, Sathish Kumar, Becker, Donald F

“…Flavoproteins catalyze a variety of reactions utilizing flavin mononucleotide or flavin adenine dinucleotide as cofactors. The oxidoreductase properties of…”
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THE RETINOBLASTOMA PROTEIN: A MASTER TUMOR SUPPRESSOR ACTS AS A LINK BETWEEN CELL CYCLE AND CELL ADHESION by Engel, B E, Cress, W D, Santiago-Cardona, P G

“…was the first tumor suppressor gene discovered. Over four decades of work have revealed that the Rb protein (pRb) is a master regulator of biological pathways…”
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Current perspectives on mitochondrial inheritance in fungi by Xu, Jianping, He, Li

“…The mitochondrion is an essential organelle of eukaryotes, generating the universal energy currency, adenosine triphosphate, through oxidative phosphorylation…”
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Apoptotic membrane dynamics in health and disease by Julian, Linda, Olson, Michael F

“…Apoptosis, also known as programmed cell death, is a fundamental homeostatic mechanism essential for normal embryonic development and the maintenance of…”
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Cytoskeleton and Golgi-apparatus interactions: a two-way road of function and structure by Egea, Gustavo, Serra-Peinado, Carla, Gavilan, Maria P, Rios, Rosa M

“…The Golgi apparatus is the result of a complex and dynamic interaction between a large variety of molecules that determine its architecture, protein and lipid…”
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Sarcomeric model of stretch-induced stress fiber reorganization by Kaunas, Roland, Hsu, Deguchi

“…Actin stress fibers (SFs) are mechanosensitive structural elements that respond to applied stress and strain to regulate cell morphology, signal transduction,…”
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Current perspectives on cadherin-cytoskeleton interactions and dynamics by Yap, Alpha, Liang, Xuan, Gomez, Guillermo

“…Cells are linked together dynamically by adhesion molecules, such as the classical cadherins. E-cadherin, which mediates epithelial cell–cell interactions,…”
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Emerging roles for the pH-sensing G protein-coupled receptors in response to acidotic stress by Sanderlin, Edward J, Justus, Calvin R, Krewson, Elizabeth A, Yang, Li. V

“…Protons (hydrogen ions) are the simplest form of ions universally produced by cellular metabolism including aerobic respiration and glycolysis. Export of…”
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Dendritic spine morphology and dynamics in health and disease by Lee, Stacey, Zhang, Huaye, Webb, Donna J

“…Dendritic spines are actin-rich structures that form the postsynaptic terminals of excitatory synapses in the brain. The development and plasticity of spines…”
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Emerging perspectives on laminopathies by Lattanzi, Giovanna, Benedetti, Sara, D'apice, Maria Rosaria, Maggi, Lorenzo, Carboni, Nicola, Scarano, Emanuela, Politano, Luisa

“…Laminopathies are a group of inherited disorders caused by mutations in the lamin A/C gene, and can affect diverse organs or tissues, or can be systemic,…”
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Dispersion relations of cytoskeleton dynamics by Wang, Ru, Lei, Lei, Sridharan, Shamira, Wang, Yingxiao, Levine, Alex J, Popescu, Gabriel

“…While it is well known that the cytoskeleton plays a fundamental role in maintaining cell shape, performing cell division, and intracellular transport, its…”
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Expression profile of plakin cross-linking proteins in short-term denervated mouse hindlimb skeletal muscle by Blouin, Patrick, Serresse, Olivier, Dorman, Sandra, Larivière, Céline

“…Purpose: Skeletal muscle atrophy linked to neuromuscular inactivity is a complex phenomenon involving widespread alteration of muscle structure and function…”
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Desmosome assembly, homeostasis, and desmosomal disease by Cirillo, Nicola

“…Cell–cell adhesion is involved in all aspects of tissue behavior in multicellular organisms, from tissue morphogenesis (regulation of cell shape, apoptosis,…”
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Mechanism and regulation of epithelial-mesenchymal transition in cancer by Reed, Irene K. Guttilla

“…During development and the pathogenesis of certain diseases, including cancer, the epithelial-mesenchymal transition (EMT) program is activated. It is…”
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Nucleoskeleton dynamics and functions in health and disease by Meinke, Peter, Makarov, Alexandr A, Thanh, Phu Le, Sadurska, Daina, Schirmer, Eric C

“…It is a common misconception to view the "cyto"-skeleton as just the filament systems in the "cyto"-plasm. In fact, the cytoskeleton extends into the nucleus…”
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Bcl-2 family-regulated apoptosis in health and disease by Kluck, Ruth

“…Apoptotic cell death is essential for embryonic development, tissue homeostasis, and a well-functioning immune system, with aberrant apoptosis contributing to…”
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Osteoblasts and their applications in bone tissue engineering by Cartmell, Sarah, Rupani, Balint

“…Tissue engineering is an emerging therapy that offers a new solution to patients suffering from bone loss. It utilizes cells derived from such sources as a…”
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