Search Results - "Celine Gongora"

High fragmentation characterizes tumour-derived circulating DNA by Mouliere, Florent, Robert, Bruno, Arnau Peyrotte, Erika, Del Rio, Maguy, Ychou, Marc, Molina, Franck, Gongora, Celine, Thierry, Alain R

“…Circulating DNA (ctDNA) is acknowledged as a potential diagnostic tool for various cancers including colorectal cancer, especially when considering the…”
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Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA by Thierry, Alain R, Mouliere, Florent, El Messaoudi, Safia, Mollevi, Caroline, Lopez-Crapez, Evelyne, Rolet, Fanny, Gillet, Brigitte, Gongora, Celine, Dechelotte, Pierre, Robert, Bruno, Del Rio, Maguy, Lamy, Pierre-Jean, Bibeau, Frederic, Nouaille, Michelle, Loriot, Virginie, Jarrousse, Anne-Sophie, Molina, Franck, Mathonnet, Muriel, Pezet, Denis, Ychou, Marc

“…Alain Thierry and his colleagues offer a new allele-specific, quantitative PCR–based method designed for the detection of point mutations and determination of…”
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Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer by Combès, Eve, Andrade, Augusto F, Tosi, Diego, Michaud, Henri-Alexandre, Coquel, Flavie, Garambois, Veronique, Desigaud, Delphine, Jarlier, Marta, Coquelle, Arnaud, Pasero, Philippe, Bonnefoy, Nathalie, Moreaux, Jerome, Martineau, Pierre, Del Rio, Maguy, Beijersbergen, Roderick L, Vezzio-Vie, Nadia, Gongora, Celine

“…Although many patients with colorectal cancer initially respond to the chemotherapeutic agent oxaliplatin, acquired resistance to this treatment remains a…”
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Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load by Mouliere, Florent, El Messaoudi, Safia, Gongora, Celine, Guedj, Anne-Sophie, Robert, Bruno, Del Rio, Maguy, Molina, Franck, Lamy, Pierre-Jean, Lopez-Crapez, Evelyne, Mathonnet, Muriel, Ychou, Marc, Pezet, Denis, Thierry, Alain R

“…Abstract Our data might suggest a very high variation in the proportion of malignant cells in colorectal tumors and/or low tumor cell clonogenicity. However,…”
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Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump by Mazard, Thibault, Causse, Annick, Simony, Joelle, Leconet, Wilhem, Vezzio-Vie, Nadia, Torro, Adeline, Jarlier, Marta, Evrard, Alexandre, Del Rio, Maguy, Assenat, Eric, Martineau, Pierre, Ychou, Marc, Robert, Bruno, Gongora, Celine

“…Despite recent advances in the treatment of colorectal cancer (CRC), tumor resistance is a frequent cause of chemotherapy failure. Therefore, new treatment…”
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Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug-Drug Interactions Are the Usual Suspects by Leenhardt, Fanny, Fiteni, Frédéric, Gauthier, Ludovic, Alexandre, Marie, Guiu, Séverine, Firmin, Nelly, Pouderoux, Stéphane, Viala, Marie, Lossaint, Gerald, Gautier, Chloé, Mollevi, Caroline, Gracia, Matthieu, Gongora, Celine, Mbatchi, Litaty, Evrard, Alexandre, Jacot, William

“…Palbociclib is a good candidate for therapeutic drug monitoring (TDM) due to its narrow therapeutic range and frequency of toxicities, particularly high-grade…”
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STING‐ATF3/type I interferon crosstalk: A potential target to improve anti‐tumour immunity in chemotherapy‐treated urothelial carcinoma by Fauvre, Alexandra, Machu, Margot, Merienne, Audrey, Vie, Nadia, Bessede, Thomas, Robin, Mathilde, Garambois, Veronique, Taffoni, Clara, Laguette, Nadine, Gervois‐Segain, Nadine, Jarry, Anne, Labarriere, Nathalie, Allory, Yves, Larbouret, Christel, Gros, Laurent, Tosi, Diego, Solit, David B., Pourquier, Philippe, Houédé, Nadine, Gongora, Celine

“…Upper Tract Urothelial Carcinomas (UTUC) are extremely aggressive and immunosuppressed tumors of the ureter or renal pelvis with a high relapse rate (>50%)…”
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Sorafenib inhibits ABCG2 and overcomes irinotecan resistance--response by Gongora, Céline

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ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro by Tsujimura, Hideki, Tamura, Tomohiko, Gongora, Celine, Aliberti, Julio, Reis e Sousa, Caetano, Sher, Alan, Ozato, Keiko

“…Dendritic cells (DCs) develop from bone marrow (BM) progenitor cells and mature in response to external signals to elicit functions important for innate and…”
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The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells by Slaninová, Věra, Heron-Milhavet, Lisa, Robin, Mathilde, Jeanson, Laura, Aissanou, Adam, Kantar, Diala, Tosi, Diego, Bréhélin, Laurent, Gongora, Céline, Djiane, Alexandre

“…YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated in cancers. In tumor cells, they have been mainly associated…”
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BAG6 promotes PINK1 signaling pathway and is essential for mitophagy by Ragimbeau, Romain, El Kebriti, Leila, Sebti, Salwa, Fourgous, Elise, Boulahtouf, Abdelhay, Arena, Giuseppe, Espert, Lucile, Turtoi, Andrei, Gongora, Céline, Houédé, Nadine, Pattingre, Sophie

“…Bcl‐2‐associated athanogen‐6 (BAG6) is a nucleocytoplasmic shuttling protein involved in protein quality control. We previously demonstrated that BAG6 is…”
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Effect of macrophage migration inhibitory factor on corneal sensitivity after laser in situ keratomileusis in rabbit by Hyon, Joon Young, Hose, Stacey, Gongora, Celine, Sinha, Debasish, O'Brien, Terrence

“…To investigate the effect of macrophage migration inhibitory factor (MIF) on corneal sensitivity after laser in situ keratomileusis (LASIK) surgery. New…”
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Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells by Denis, Vincent, Cassagnard, Nadège, Del Rio, Maguy, Cornillot, Emmanuel, Bec, Nicole, Larroque, Christian, Jeanson, Laura, Jarlier, Marta, Combès, Eve, Robert, Bruno, Gongora, Céline, Martineau, Pierre, Dariavach, Piona

“…Spleen tyrosine kinase (Syk) expression have been both positively and negatively associated with tumorigenesis. Our goal was to evaluate the contribution of…”
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BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy by Sebti, Salwa, Prébois, Christine, Pérez-Gracia, Esther, Bauvy, Chantal, Desmots, Fabienne, Pirot, Nelly, Gongora, Céline, Bach, Anne-Sophie, Hubberstey, Andrew V., Palissot, Valérie, Berchem, Guy, Codogno, Patrice, Linares, Laetitia K., Liaudet-Coopman, Emmanuelle, Pattingre, Sophie

“…Autophagy is regulated by posttranslational modifications, including acetylation. Here we show that HLA-B—associated transcript 3 (BAT3) is essential for basal…”
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Gamma Interferon Triggers Interaction between ICSBP (IRF-8) and TEL, Recruiting the Histone Deacetylase HDAC3 to the Interferon-Responsive Element by Kuwata, Takeshi, Gongora, Celine, Kanno, Yuka, Sakaguchi, Kazuyasu, Tamura, Tomohiko, Kanno, Tomohiko, Basrur, Venkatesha, Martinez, Robert, Appella, Ettore, Golub, Todd, Ozato, Keiko

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Efficacy of novel allogeneic cancer cells vaccine to treat colorectal cancer by Alzeeb, George, Tortorelli, Corinne, Taleb, Jaqueline, De Luca, Fanny, Berge, Benoit, Bardet, Chloé, Limagne, Emeric, Brun, Marion, Chalus, Lionel, Pinteur, Benoit, Bravetti, Paul, Gongora, Céline, Apetoh, Lionel, Ghiringhelli, Francois

“…Colorectal cancer (CRC) remains a significant global health burden, emphasizing the need for innovative treatment strategies. 95% of the CRC population are…”
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Strategies for clinical development of monoclonal antibodies beyond first-in-human trials: tested doses and rationale for dose selection by Viala, Marie, Vinches, Marie, Alexandre, Marie, Mollevi, Caroline, Durigova, Anna, Hayaoui, Nadia, Homicsko, Krisztian, Cuenant, Alice, Gongora, Céline, Gianni, Luca, Tosi, Diego

“…Background: Our previous survey on first-in-human trials (FIHT) of monoclonal antibodies (mAbs) showed that, due to their limited toxicity, the recommended…”
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Synthesis and in vitro antitumour activity of carboplatin analogues containing functional handles compatible for conjugation to drug delivery systems by Rečnik, Lisa-Maria, Cantelli, Christophe, Fersing, Cyril, Gongora, Céline, Pouget, Jean-Pierre, Lisowski, Vincent

“…[Display omitted] We describe herein the synthesis of a series of carboplatin derivatives with different functional groups at position 3 of the cyclobutane…”
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Multiplexed-Based Assessment of DNA Damage Response to Chemotherapies Using Cell Imaging Cytometry by Vezzio-Vié, Nadia, Kong-Hap, Marie-Alice, Combès, Eve, Andrade, Augusto Faria, Del Rio, Maguy, Pasero, Philippe, Theillet, Charles, Gongora, Céline, Pourquier, Philippe

“…The current methods for measuring the DNA damage response (DDR) are relatively labor-intensive and usually based on Western blotting, flow cytometry, and/or…”
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Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer by Ogier, Charline, Colombo, Pierre-Emmanuel, Bousquet, Corinne, Canterel-Thouennon, Lucile, Sicard, Pierre, Garambois, Véronique, Thomas, Gaëlle, Gaborit, Nadège, Jarlier, Marta, Pirot, Nelly, Pugnière, Martine, Vie, Nadia, Gongora, Céline, Martineau, Pierre, Robert, Bruno, Pèlegrin, André, Chardès, Thierry, Larbouret, Christel

“…Neuregulin 1 (NRG1), a ligand for HER3 and HER4 receptors, is secreted by both pancreatic tumor cells (PC) and cancer-associated fibroblasts (CAFs), the latter…”
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