Search Results - "Celias, Daiana"

The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake by de Mingo Pulido, Álvaro, Hänggi, Kay, Celias, Daiana P., Gardner, Alycia, Li, Jie, Batista-Bittencourt, Bruna, Mohamed, Eslam, Trillo-Tinoco, Jimena, Osunmakinde, Olabisi, Peña, Reymi, Onimus, Alexis, Kaisho, Tsuneyasu, Kaufmann, Johanna, McEachern, Kristen, Soliman, Hatem, Luca, Vincent C., Rodriguez, Paulo C., Yu, Xiaoqing, Ruffell, Brian

“…Blockade of the inhibitory receptor TIM-3 shows efficacy in cancer immunotherapy clinical trials. TIM-3 inhibits production of the chemokine CXCL9 by XCR1+…”
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Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells by Motran, Claudia Cristina, Silvane, Leonardo, Chiapello, Laura Silvina, Theumer, Martin Gustavo, Ambrosio, Laura Fernanda, Volpini, Ximena, Celias, Daiana Pamela, Cervi, Laura

“…The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the…”
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Helminths Turning on the NLRP3 Inflammasome: Pros and Cons by Celias, Daiana Pamela, Motrán, Claudia Cristina, Cervi, Laura

“…Helminth infections can activate multimeric protein complexes called inflammasomes. In this forum we summarize the main effects of the NLRP3 inflammasome…”
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LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition by Ming, Qianqian, Celias, Daiana P., Wu, Chao, Cole, Aidan R., Singh, Srishti, Mason, Charlotte, Dong, Shen, Tran, Timothy H., Amarasinghe, Gaya K., Ruffell, Brian, Luca, Vincent C.

“…The immune checkpoint receptor lymphocyte activation gene 3 protein (LAG3) inhibits T cell function upon binding to major histocompatibility complex class II…”
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Cathepsin L3 From Fasciola hepatica Induces NLRP3 Inflammasome Alternative Activation in Murine Dendritic Cells by Celias, Daiana Pamela, Corvo, Ileana, Silvane, Leonardo, Tort, José Francisco, Chiapello, Laura Silvina, Fresno, Manuel, Arranz, Alicia, Motrán, Claudia Cristina, Cervi, Laura

“…The production of IL-1-family cytokines such as IL-1β and IL-18 is finely regulated by inflammasome activation after the recognition of pathogens associated…”
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Detection of exogenous DNA uptake by murine dendritic cells by Celias, Daiana P., de Mingo Pulido, Álvaro, Ruffell, Brian

“…This protocol has been developed to measure exogenous DNA uptake by murine dendritic cells (DCs) using supernatant containing cellular debris, which allows for…”
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Dendritic cells and parasites: from recognition and activation to immune response instruction by Motran, Claudia Cristina, Ambrosio, Laura Fernanda, Volpini, Ximena, Celias, Daiana Pamela, Cervi, Laura

“…The effective defense against parasite infections requires the ability to mount an appropriate and controlled specific immune response able to eradicate the…”
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A Vaccine Based on Kunitz-Type Molecule Confers Protection Against Fasciola hepatica Challenge by Inducing IFN-γ and Antibody Immune Responses Through IL-17A Production by Silvane, Leonardo, Celias, Daiana Pamela, Romagnoli, Pablo Alberto, Maletto, Belkys Angélica, Sanchez Vallecillo, María Fernanda, Chiapello, Laura Silvina, Palma, Santiago Daniel, Allemandi, Daniel Alberto, Sanabria, Rodrigo Eduardo Fabrizio, Pruzzo, César Iván, Motrán, Claudia Cristina, Cervi, Laura

“…is helminth parasite found around the world that causes fasciolosis, a chronic disease affecting mainly cattle, sheep, and occasionally humans. Triclabendazole…”
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Abstract 678: Investigating the mechanisms involved in HMGB1-dependent DNA uptake and STING activation in dendritic cells by Celias, Daiana P., Hänggi, Kay, Ruffell, Brian

“…Background: The cGAS-STING pathway is critical for the development of anti-tumor immunity. Activation of host STING can occur by sensing of extracellular DNA…”
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Fasciola hepatica Fatty Acid Binding Protein (Fh12) inhibits the activation of murine dendritic cells by Ruiz-Jiménez, Caleb, Celias, Daiana, Silvane, Leonardo, Cervi, Laura, Espino, Ana M.

“…Fasciola hepatica, is a helminth that excretes-secretes different proteins that modulate cells of the immune system, generating anti-inflammatory responses. It…”
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Abstract 655: Necroptosis promotes tumor growth through IL1-alpha release and recruitment of immunosuppressive myeloid cells by Hänggi, Kay, Keske, Aysenur, Gardner, Alycia, Li, Jie, Osunmakinde, Olabisi, Celias, Daiana, Beg, Amer, Ruffell, Brian

“…Programmed cell death (PCD) was originally limited to apoptosis, but now includes pyroptosis, ferroptosis, necroptosis, and paraptosis. Necroptosis has…”
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Fasciola hepatica fatty acid binding protein (Fh12) induces apoptosis and tolerogenic properties in murine bone marrow derived dendritic cells by Ruiz-Jiménez, Caleb, Celias, Daiana, Valdés, Bianca, Ramos-Pérez, Willy D., Cervi, Laura, Espino, Ana M.

“…In a previous study we demonstrated that Fasciola hepatica fatty acid binding protein (Fh12) significantly suppress macrophage function by inhibiting IL-6,…”
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