Search Results - "Celia C. H. Chen"

Structure of Phosphorylated Enzyme I, the Phosphoenolpyruvate: Sugar Phosphotransferase System Sugar Translocation Signal Protein by Teplyakov, Alexey, Lim, Kap, Zhu, Peng-Peng, Kapadia, Geeta, Chen, Celia C. H., Schwartz, Jennifer, Howard, Andrew, Reddy, Prasad T., Peterkofsky, Alan, Herzberg, Osnat

“…Bacterial transport of many sugars, coupled to their phosphorylation, is carried out by the phosphoenolpyruvate (PEP):sugar phosphotransferase system and…”
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Swiveling Domain Mechanism in Pyruvate Phosphate Dikinase by Lim, Kap, Read, Randy J, Chen, Celia C. H, Tempczyk, Aleksandra, Wei, Min, Ye, Dongmei, Wu, Chun, Dunaway-Mariano, Debra, Herzberg, Osnat

“…Pyruvate phosphate dikinase (PPDK) catalyzes the reversible conversion of phosphoenolpyruvate (PEP), AMP, and Pi to pyruvate and ATP. The enzyme contains two…”
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Degradation Pathway of the Phosphonate Ciliatine:  Crystal Structure of 2-Aminoethylphosphonate Transaminase by Chen, Celia C. H, Zhang, H, Kim, A. D, Howard, A, Sheldrick, G. M, Mariano-Dunaway, D, Herzberg, O

“…Phosphonates allow certain organisms to thrive in otherwise hostile environments, and 2-aminoethylphosphonate (AEP) is a precursor of many cellular…”
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Pyruvate Site of Pyruvate Phosphate Dikinase:  Crystal Structure of the Enzyme−Phosphonopyruvate Complex, and Mutant Analysis by Herzberg, Osnat, Chen, Celia C. H, Liu, Sijiu, Tempczyk, Aleksandra, Howard, Andrew, Wei, Min, Ye, Dongmei, Dunaway-Mariano, Debra

“…Crystals of pyruvate phosphate dikinase in complex with a substrate analogue inhibitor, phosphonopyruvate (K i = 3 μM), have been obtained in the presence of…”
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Structure and Kinetics of Phosphonopyruvate Hydrolase from Voriovorax sp. Pal2:  New Insight into the Divergence of Catalysis within the PEP Mutase/Isocitrate Lyase Superfamily by Chen, Celia C. H, Han, Ying, Niu, Weiling, Kulakova, Anna N, Howard, Andrew, Quinn, John P, Dunaway-Mariano, Debra, Herzberg, Osnat

“…Phosphonopyruvate (P-pyr) hydrolase (PPH), a member of the phosphoenolpyruvate (PEP) mutase/isocitrate lyase (PEPM/ICL) superfamily, hydrolyzes P-pyr and…”
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Structures of the Acyl−Enzyme Complexes of the Staphylococcus aureus β-Lactamase Mutant Glu166Asp:Asn170Gln with Benzylpenicillin and Cephaloridine by Chen, Celia C. H, Herzberg, Osnat

“…The serine-β-lactamases hydrolyze β-lactam antibiotics in a reaction that proceeds via an acyl−enzyme intermediate. The double mutation, E166D:N170Q, of the…”
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Swiveling-Domain Mechanism for Enzymatic Phosphotransfer between Remote Reaction Sites by Herzberg, Osnat, Celia C. H. Chen, Kapadia, Geeta, McGuire, Marielena, Carroll, Lawrence J., Noh, Seong J., Dunaway-Mariano, Debra

“…The crystal structure of pyruvate phosphate dikinase, a histidyl multiphosphotransfer enzyme that synthesizes adenosine triphosphate, reveals a three-domain…”
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Elimination of the Hydrolytic Water Molecule in a Class A β-Lactamase Mutant:  Crystal Structure and Kinetics by Zawadzke, Laura E, Chen, Celia C. H, Banerjee, Soojay, Li, Zhong, Wäsch, Susana, Kapadia, Geeta, Moult, John, Herzberg, Osnat

“…Two site-directed mutant enzymes of the class A β-lactamase from Staphylococcus aureus PC1 were produced with the goal of blocking the site that in the native…”
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Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily by Chen, Celia C H, Han, Ying, Niu, Weiling, Kulakova, Anna N, Howard, Andrew, Quinn, John P, Dunaway-Mariano, Debra, Herzberg, Osnat

“…Phosphonopyruvate (P-pyr) hydrolase (PPH), a member of the phosphoenolpyruvate (PEP) mutase/isocitrate lyase (PEPM/ICL) superfamily, hydrolyzes P-pyr and…”
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Deamino-Oxytocin and 1-γ-Mercaptobutyric Acid-Oxytocin: X-ray Crystallographic Data by Low, Barbara W., Celia C. H. Chen

“…X-ray studies of crystalline deamino-oxytocin (1-β -mercaptopropionic acid-oxytocin) have established the existence of both wet and dry forms. A remarkable…”
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Swiveling Domain Mechanism in Pyruvate Phosphate Dikinase by Lim, Kap, Read, Ry J, Chen, Celia CH, Tempczyk, Aleksra, Wei, Min, Ye, Dongmei, Wu, Chun, Dunaway-Mariano, Debra, Herzberg, Osnat

“…Pyruvate phosphate dikinase (PPDK) catalyzes the reversible conversion of phosphoenolpyruvate (PEP), AMP, and P sub(i) to pyruvate and ATP. The enzyme contains…”
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