Characteristics of a COVID-19 confirmed case series in primary care (COVID-19-PC project): a cross-sectional study

To estimate the prevalence of symptoms and signs related to a COVID-19 case series confirmed by polymerase chain reaction (PCR) for SARS-CoV-2. Risk factors and the associated use of health services will also be analysed. Observational, descriptive, retrospective case series study. The study was per...

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Published in:	BMC family practice Vol. 22; no. 1; p. 66
Main Authors:	Rogero-Blanco, Eloisa, González-García, Vera, García, Rodrigo Medina, Muéoz-Molina, Pilar, Machin-Hamalainen, Santiago, López-Rodríguez, Juan A, López, Abellán, Ramón, Francisco, Apoita, Barranco, de Quirós, Marta Bernardo, Corral, Carlos Bernardo, María, Manuel, Velasco, Bosom, Ãlvaro, Marta Casado, Sanz, Carlos Casado, Pilar, M, Sánchez, Chaves, González, Pilar Cubero, De la Torre Buedo, Paulino, Muéiz, Eva Docavo, Díaz, Patricia Fernández, Valeiras, Raquel Ferrer, Ranz, Teresa Garcés, Damián, José, Galeano, García, Celeste, MÂª, Ciriano, Gómez, Ignacio, Jorge, Criado, Gómez, Soledad, María, López, Herranz, Calatayud, Marta Hontanilla, Gallar, Josefina Hurtado, Fernández, Jorge Jerez, Rodríguez, Pablo López, Antonio, Juan, Hamalainen, Machín, Rodríguez, Santiago Macías, Becerra, Jacinto Marín, Teresa, María, Fernández, Mateo, García, Raquel Medina, Rodríguez, Rodrigo Moldes, Paz, Mari, Cebolla, Morcillo, Box, Sara Pajares, Goncalves, Purificación Palacios, Berdeja, Lydia Preto, Artur, Guilherme, Orzando, Prieto, Araencibia, Asunción Quintana, Blanco, Lara Rogero, Eloísa, María, Fernández, Rossignoli, Navarro, Tomas San Telesforo, José, María, Barreiro, Sánchez, Franco, Sara Santos, Vila i Torello, Laura, Valeiras, Clara Ferrer, Rodríguez, Teresa Alejano, Isabel, Ana, Sacristán, Barbero, Camino, Pedro Barranco, García, María Calvo, Calera, Isabel Diaz, Concepción, M, Hernández, Drak, Barona, Yasmin Fuentes, Carlos, Juan, Gómez, Galtier, Fernández, Leticia Gómez, Esperanza, María, García, González, Alocén, Vera Horcajada, Galán, Rocío Hortelano, Isabel, María, Molina, Muéoz, Carnero, Navarro, Sánchez, Belén Pérez, Carlos, Francisco, Baquero, Sáenz García, Garrido, Isabel Torralba, Iván, Vicente, García, Zufia, Javier, Francisco, Alonso, Andrea Valcárcel
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 08-04-2021 BioMed Central BMC
Subjects:	Chronic obstructive pulmonary disease Confidence intervals Coronavirus Infections Coronaviruses COVID-19 COVID-19 - diagnosis COVID-19 - epidemiology COVID-19 - physiopathology COVID-19 [Supplementary Concept] COVID-19 Nucleic Acid Testing - statistics & numerical data Cross-sectional studies Demography Diabetes Disease Transmission, Infectious - statistics & numerical data Dyspnea Emergency medical care Female Fever Health care Hospitals Humans Infections Male Methods Middle Aged Patient Acceptance of Health Care - statistics & numerical data Patients Physicians Pneumonia Pneumonia, Viral - diagnosis Pneumonia, Viral - epidemiology Pneumonia, Viral - etiology Primary care Primary Health Care Primary Health Care - methods Primary Health Care - statistics & numerical data Public health Pulmonary manifestations of general diseases Risk Factors SARS-CoV-2 - isolation & purification Severe acute respiratory syndrome coronavirus 2 Severity of Illness Index Sociodemographics Socioeconomic Factors Spain - epidemiology Statistics Symptom Assessment - methods Symptom Assessment - statistics & numerical data Variables Viral Spain Coronavirus Infections Pneumonia Primary Health Care COVID-19 [Supplementary Concept] Viral
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Summary:	To estimate the prevalence of symptoms and signs related to a COVID-19 case series confirmed by polymerase chain reaction (PCR) for SARS-CoV-2. Risk factors and the associated use of health services will also be analysed. Observational, descriptive, retrospective case series study. The study was performed at two Primary Care Health Centres located in Madrid, Spain. The subjects studied were all PCR SARS-CoV-2 confirmed cases older than 18 years, diagnosed from the beginning of the community transmission (March 13) until April 15, 2020. We collected sociodemographic, clinical, health service utilization and clinical course variables during the following months. All data was gathered by their own attending physician, and electronic medical records were reviewed individually. A descriptive analysis was carried out and a Poisson regression model was adjusted to study associated factors to Health Services use. Out of the 499 patients studied from two health centres, 55.1% were women and mean age was 58.2 (17.3). 25.1% were healthcare professionals. The most frequent symptoms recorded related to COVID-19 were cough (77.9%; CI 95% 46.5-93.4), fever (77.7%; CI95% 46.5-93.4) and dyspnoea (54.1%, CI95% 46.6-61.4). 60.7% were admitted to hospital. 64.5% first established contact with their primary care provider before going to the hospital, with a mean number of 11.4 Healthcare Providers Encounters with primary care during all the follow-up period. The number of visit-encounters with primary care was associated with being male [IRR 1.072 (1.013, 1.134)], disease severity {from mild respiratory infection [IRR 1.404 (1.095, 1.801)], up to bilateral pneumonia [IRR 1.852 (1.437,2.386)]}, and the need of a work leave [IRR 1.326 (1.244, 1.413]. Symptoms and risk factors in our case series are similar to those in other studies. There was a high number of patients with atypical unilateral or bilateral pneumonia. Care for COVID has required a high use of healthcare resources such as clinical encounters and work leaves.
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ISSN:	1471-2296 1471-2296
DOI:	10.1186/s12875-021-01419-7