Search Results - "Celes, Mara Rúbia"

Dantrolene improves in vitro structural changes induced by serum from Trypanosoma cruzi-infected mice by Malvestio, Lygia M., Celes, Mara Rúbia N., Jelicks, Linda A., Tanowitz, Herbert B., Prado, Cibele M.

“…Dystrophin, an important protein of the dystrophin-glycoprotein complex, has been implicated in the pathogenesis of experimental Chagas disease. It is…”
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Calpain-mediated dystrophin disruption may be a potential structural culprit behind chronic doxorubicin-induced cardiomyopathy by Campos, Erica C., O'Connell, João L., Malvestio, Lygia M., Romano, Minna M. Dias, Ramos, Simone G., Celes, Mara Rúbia N., Prado, Cibele M., Simões, Marcus V., Rossi, Marcos A.

“…The critical importance of dystrophin to cardiomyocyte contraction and sarcolemmal and myofibers integrity, led us to test the hypothesis that dystrophin…”
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The Colombian Strain of Trypanosoma cruzi Induces a Proinflammatory Profile, Neuronal Death, and Collagen Deposition in the Intestine of C57BL/6 Mice Both during the Acute and Early Chronic Phase by do Carmo Neto, José Rodrigues, da Costa, Arthur Wilson Florêncio, Braga, Yarlla Loyane Lira, Lucio, Fernanda Hélia, dos Santos Martins, Ana Luisa Monteiro, dos Reis, Marlene Antônia, de Oliveira, Flávia Aparecida, Celes, Mara Rúbia Nunes, da Silva, Marcos Vinicius, Oliveira, Milton Adriano Pelli, Machado, Juliana Reis

“…The objective of this study was to evaluate the histopathological changes caused by infection with the Colombian strain of Trypanosoma cruzi (T. cruzi) in the…”
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Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis by Celes, Mara Rúbia N, Torres-Dueñas, Diego, Alves-Filho, José C, Duarte, Djane B, Cunha, Fernando Q, Rossi, Marcos A

“…OBJECTIVE:The present study describes intercalated disc remodeling under both protein expression and structural features in experimental severe sepsis induced…”
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Toxicity Assessment of New Ag-ZnO/AgO Nanocomposites: An In Vitro and In Vivo Approach by do Carmo Neto, José Rodrigues, Franco, Pablo Igor Ribeiro, Braga, Yarlla Loyane Lira, de Oliveira, Jordana Fernandes, Perini, Hugo Felix, Albuquerque, Luís Fernando Duarte, Martins, Danieli Brolo, Helmo, Fernanda Rodrigues, Andrade, Anderson Assunção, Miguel, Marina Pacheco, Celes, Mara Rúbia Nunes, Rocha, Thiago Lopes, Almeida Silva, Anielle Christine, Machado, Juliana Reis, da Silva, Marcos Vinícius

“…Zinc oxide nanoparticles (ZnO NPs) are metal oxide nanomaterials, which are important for several applications: antibacterial, anthelmintic, antiprotozoal and…”
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Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi by Pelli de Oliveira, Milton Adriano, Lino-Júnior, Ruy de Sousa, Celes, Mara Rúbia Nunes, Machado, Juliana Reis, Monteiro, Maria Luiza Gonçalves dos Reis, da Silva, Aline Cristina Souza, Aparecida da Silva, Crislaine, de Oliveira, Pollyana Guimarães, Matos Cascudo, Natália Carasek, de Oliveira, Wendyson Duarte, de Almeida, Vera Lúcia, Vinícius da Silva, Marcos, Corrêa, Rosana Rosa Miranda

“…Inflammatory response in Chagas disease is related to parasite and host factors. However, immune system regulation has not been fully elucidated. Thus, this…”
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Correlation between intestinal BMP2, IFNγ, and neural death in experimental infection with Trypanosoma cruzi by do Carmo Neto, José Rodrigues, Vinicius da Silva, Marcos, Braga, Yarlla Loyane Lira, Florencio da Costa, Arthur Wilson, Fonseca, Simone Gonçalves, Nagib, Patricia Resende Alô, Nunes Celes, Mara Rúbia, Oliveira, Milton Adriano Pelli, Machado, Juliana Reis

“…Megacolon is one of the main late complications of Chagas disease, affecting approximately 10% of symptomatic patients. However, studies are needed to…”
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Neonatal Sepsis and Inflammatory Mediators by Celes, Mara Rúbia Nunes, Corrêa, Rosana Rosa Miranda, Monteiro, Maria Luiza Gonçalves dos Reis, Etchebehere, Renata Margarida, de Menezes, Liliana Borges, Vinícius da Silva, Marcos, Soave, Danilo Figueiredo, Machado, Juliana Reis, Reis, Marlene Antônia dos

“…Neonatal sepsis is a major cause of morbidity and mortality and its signs and symptoms are nonspecific, which makes the diagnosis difficult. The routinely used…”
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Activation of Both the Calpain and Ubiquitin-Proteasome Systems Contributes to Septic Cardiomyopathy through Dystrophin Loss/Disruption and mTOR Inhibition by Freitas, Ana Caroline Silva, Figueiredo, Maria Jose, Campos, Erica Carolina, Soave, Danilo Figueiredo, Ramos, Simone Gusmao, Tanowitz, Herbert B, Celes, Mara Rúbia N

“…Cardiac dysfunction caused by the impairment of myocardial contractility has been recognized as an important factor contributing to the high mortality in…”
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Curcumin Attenuates Doxorubicin-Induced Cardiac Oxidative Stress and Increases Survival in Mice by Arruda, Felipe S, Tomé, Fernanda D, Milhomem, Anália C, Franco, Pablo I R, Justino, Allisson B, Franco, Rodrigo R, Campos, Erica C, Espindola, Foued S, Soave, Danilo F, Celes, Mara Rubia N

“…Doxorubicin (DOX) is a potent chemotherapeutic agent used to treat multiple types of cancer, but its clinical application is limited by cardiotoxicity, mainly…”
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Increased Atrial β-Adrenergic Receptors and GRK-2 Gene Expression Can Play a Fundamental Role in Heart Failure After Repair of Congenital Heart Disease with Cardiopulmonary Bypass by Oliveira, Marcela Silva, Carmona, Fabio, Vicente, Walter V. A., Manso, Paulo H., Mata, Karina M., Celes, Mara Rúbia, Campos, Erica C., Ramos, Simone G.

“…Surgeries to correct congenital heart diseases are increasing in Brazil and worldwide. However, even with the advances in surgical techniques and perfusion,…”
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Advax4 delta inulin combination adjuvant together with ECMX, a fusion construct of four protective mTB antigens, induces a potent Th1 immune response and protects mice against Mycobacterium tuberculosis infection by de Paula Oliveira Santos, Bruno, Trentini, Monalisa Martins, Machado, Renato Beilner, Rúbia Nunes Celes, Mara, Kipnis, André, Petrovsky, Nikolai, Junqueira-Kipnis, Ana Paula

“…Tuberculosis (TB) remains a main public health concern and 10.4 million new cases occurred in 2015 around the world. BCG is the only approved vaccine against…”
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Doxorubicin-induced Cardiotoxicity and Cardioprotective Agents: Classic and New Players in the Game by Dos Santos Arruda, Felipe, Tomé, Fernanda Dias, Miguel, Marina Pacheco, de Menezes, Liliana Borges, Nagib, Patrícia Resende Alo, Campos, Erica Carolina, Soave, Danilo Figueiredo, Celes, Mara Rúbia Nunes

“…Doxorubicin (DOX) is a cytostatic antibiotic from the class of anthracyclines widely used in chemotherapeutic cancer treatments. Despite the efficiency against…”
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High-Lard and High-Cholesterol Diet, but not High-Lard Diet, Leads to Metabolic Disorders in a Modified Dyslipidemia Model by Muniz, Lidiane B, Alves-Santos, Aline M, Camargo, Fabricio, Martins, Danieli Brolo, Celes, Mara Rubia N, Naves, Maria Margareth V

“…In view of the increased global prevalence of cardiovascular and hepatic diseases, the diet lipid content and its relationship with the accumulation of fat in…”
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Cardiac Chagas Disease: MMPs, TIMPs, Galectins, and TGF-β as Tissue Remodelling Players by Machado, Juliana Reis, Celes, Mara Rúbia Nunes, dos Reis, Marlene Antônia, Silva, Bárbara Oliveira, Lamounier, Amanda Borges, Silva, Beatriz Aquino, Braga, Yarlla Loyane Lira, do Carmo Neto, Jose Rodrigues, da Costa, Arthur Wilson Florencio, de Oliveira, Flávia Aparecida

“…A century after the discovery of Chagas disease, studies are still needed to establish the complex pathophysiology of this disease. However, it is known that…”
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The Influence of IL-11 on Cardiac Fibrosis in Experimental Models: A Systematic Review by Braga, Yarlla Loyane Lira, do Carmo Neto, José Rodrigues, Franco, Pablo Igor Ribeiro, Helmo, Fernanda Rodrigues, Dos Reis, Marlene Antônia, de Oliveira, Flávia Aparecida, Celes, Mara Rúbia Nunes, da Silva, Marcos Vinícius, Machado, Juliana Reis

“…Fibrosis is one of the main factors that impair the function of many organs. In the heart, fibrosis leads to contractile dysfunction and arrhythmias, which are…”
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Polyphenols-Rich Fraction from Annona muricata Linn. Leaves Attenuates Oxidative and Inflammatory Responses in Neutrophils, Macrophages, and Experimental Lung Injury by Saraiva, André, Justino, Allisson, Franco, Rodrigo, Silva, Heitor, Arruda, Felipe, Klein, Sandra, Celes, Mara, Goulart, Luiz, Espindola, Foued

“…Annona muricata Linn. is a common plant found in the warmest regions of South and Central America and its use in traditional medicine has been reported for the…”
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ACE2 Down-Regulation May Act as a Transient Molecular Disease Causing RAAS Dysregulation and Tissue Damage in the Microcirculatory Environment Among COVID-19 Patients by Ramos, Simone Gusmão, Rattis, Bruna Amanda da Cruz, Ottaviani, Giulia, Celes, Mara Rubia Nunes, Dias, Eliane Pedra

“…Severe acute respiratory syndrome coronavirus 2, the etiologic agent of coronavirus disease 2019 (COVID-19) and the cause of the current pandemic, produces…”
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The Fate of the Tumor in the Hands of Microenvironment: Role of TAMs and mTOR Pathway by Nagib, Patrícia Resende Alo, de Menezes, Liliana Borges, Tomé, Fernanda Dias, Miguel, Marina Pacheco, Soave, Danilo Figueiredo, Celes, Mara Rúbia Nunes

“…Since 2000, written with elegance and accuracy, Hanahan and Weinberg have proposed six major hallmarks of cancer and, together, they provide great advances to…”
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Intercellular junctions in sepsis by Rossi, Marcos A, Celes, Mara Rúbia N

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