Search Results - "Celej, María Soledad"
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Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease
Published in Biochemical journal (01-11-2015)“…Parkinson's disease (PD) is an age-related movement disorder characterized by a progressive degeneration of dopaminergic neurons in the midbrain. Although the…”
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Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure
Published in Biochemical journal (01-05-2012)“…Parkinson's disease is an age-related movement disorder characterized by the presence in the mid-brain of amyloid deposits of the 140-amino-acid protein AS…”
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Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death
Published in Scientific reports (03-03-2017)“…Autophagy is a fundamental cellular homeostatic mechanism, whereby cells autodigest parts of their cytoplasm for removal or turnover. Neurodegenerative…”
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Binding of the Highly Toxic Tetracycline Derivative, Anhydrotetracycline, to Bovine Serum Albumin
Published in Biological & Pharmaceutical Bulletin (2011)“…Tetracycline (TC) derivatives are extensively used as antibiotics in human and animal medicine and, very recently, they have been screened as…”
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Amyloid oligomerization of the Parkinson's disease related protein α‐synuclein impacts on its curvature‐membrane sensitivity
Published in Journal of neurochemistry (01-11-2018)“…The amyloid aggregation of the presynaptic protein α‐synuclein (AS) is pathognomonic of Parkinson's disease and other neurodegenerative disorders…”
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Protein stability induced by ligand binding correlates with changes in protein flexibility
Published in Protein science (01-07-2003)“…The interaction between ligands and proteins usually induces changes in protein thermal stability with modifications in the midpoint denaturation temperature,…”
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Protein Unfolding Coupled to Ligand Binding: Differential Scanning Calorimetry Simulation Approach
Published in Journal of chemical education (01-01-2005)“…The aim of this work is to present the physicochemical basis underlying the changes in protein thermostability upon ligand binding. The article is addressed to…”
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Amperometric Glucose Biosensor Based on Gold-Dispersed Carbon Paste
Published in Electroanalysis (New York, N.Y.) (01-09-1998)“…Metallized carbon paste electrodes containing glucose oxidase have demonstrated to be very useful for the rapid, selective, and sensitive glucose…”
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Alpha-Synuclein Amyloid Oligomers Exhibit Beta-Sheet Antiparallel Structure as Revealed by FTIR Spectroscopy
Published in Biophysical journal (31-01-2012)Get full text
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