Search Results - "Ceglia, Valentina"
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Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines
Published in Frontiers in immunology (13-01-2022)“…CD40 is a potent activating receptor expressed on antigen-presenting cells (APCs) of the immune system. CD40 regulates many aspects of B and T cell immunity…”
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A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires
Published in Frontiers in immunology (30-11-2021)“…Common approaches for monitoring T cell responses are limited in their multiplexity and sensitivity. In contrast, deep sequencing of the T Cell Receptor (TCR)…”
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HIV Protease Inhibitors Apoptotic Effect in SH-SY5Y Neuronal Cell Line
Published in Cellular physiology and biochemistry (01-09-2016)“…Background: Prophylactic treatment regimens to prevent mother-to-child HIV transmission include protease inhibitors Lopinavir and Ritonavir. Lopinavir and…”
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Anti-CD40 Antibodies Fused to CD40 Ligand Have Superagonist Properties
Published in The Journal of immunology (1950) (15-10-2021)“…Abstract CD40 is a potent activating receptor within the TNFR family expressed on APCs of the immune system, and it regulates many aspects of B and T cell…”
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Dendritic cell targeting anti-CD40 antibody-CD40L-HIV-1 vaccines are adjuvant intrinsic
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Soluble CD40L and agonistic anti-CD40 monoclonal antibody are adjuvants used in vaccination settings. Vaccines based on anti-CD40 antibodies fused to…”
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Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity
Published in Blood (18-04-2019)“…Filamin A (FLNa) links the cell membrane with the cytoskeleton and is central in several cellular processes. Heterozygous mutations in the X-linked FLNA gene…”
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Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity
Published in Blood (18-04-2019)“…Filamin A (FLNa) links the cell membrane with the cytoskeleton and is central in several cellular processes. Heterozygous mutations in the X-linked gene are…”
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Journal Article