Search Results - "Ceder, Rebecca"

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury by Kohonen, Pekka, Parkkinen, Juuso A., Willighagen, Egon L., Ceder, Rebecca, Wennerberg, Krister, Kaski, Samuel, Grafström, Roland C.

“…Predicting unanticipated harmful effects of chemicals and drug molecules is a difficult and costly task. Here we utilize a ‘big data compacting and data…”
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YAP1 is a potential biomarker for cetuximab resistance in head and neck cancer by Jerhammar, Fredrik, Johansson, Ann-Charlotte, Ceder, Rebecca, Welander, Jenny, Jansson, Agneta, Grafström, Roland C, Söderkvist, Peter, Roberg, Karin

“…Summary Objectives Targeted therapy against the epidermal growth factor receptor (EGFR) only variably represents a therapeutic advance in head and neck…”
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Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma by Jerhammar, Fredrik, Ceder, Rebecca, Garvin, Stina, Grénman, Reidar, Grafström, Roland C., Roberg, Karin

“…Radiotherapy remains the backbone of head and neck cancer therapy but response is sometimes impeded by tumor radioresistance. Identifying predictive biomarkers…”
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MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer by Hansson, Magnus L, Behmer, Stefanie, Ceder, Rebecca, Mohammadi, Sadollah, Preta, Giulio, Grafström, Roland C, Fadeel, Bengt, Wallberg, Annika E

“…Mastermind-like 1 (MAML1) is a transcriptional coregulator of activators in various signaling pathways, such as Notch, p53, myocyte enhancer factor 2C (MEF2C)…”
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CD44 expression in oro-pharyngeal carcinoma tissues and cell lines by Rajarajan, Abirami, Stokes, Angela, Bloor, Balvinder K, Ceder, Rebecca, Desai, Hemini, Grafström, Roland C, Odell, Edward W

“…Expression of CD44, a transmembrane hyaluronan-binding glycoprotein, is variably considered to have prognostic significance for different cancers, including…”
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The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing by Kohonen, Pekka, Benfenati, Emilio, Bower, David, Ceder, Rebecca, Crump, Michael, Cross, Kevin, Grafström, Roland C., Healy, Lyn, Helma, Christoph, Jeliazkova, Nina, Jeliazkov, Vedrin, Maggioni, Silvia, Miller, Scott, Myatt, Glenn, Rautenberg, Michael, Stacey, Glyn, Willighagen, Egon, Wiseman, Jeff, Hardy, Barry

“…The aim of the SEURAT‐1 (Safety Evaluation Ultimately Replacing Animal Testing‐1) research cluster, comprised of seven EU FP7 Health projects co‐financed by…”
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History, Implementation and Current Use of the IFCC-IUPAC's Nomenclature for Properties and Units (NPU) Terminology in Denmark, Norway and Sweden by Antonsen, Steen, Amundsen, Erik Koldberg, Ceder, Rebecca, Toska, Karin, Tollånes, Mette Christophersen, Hansen, Young Bae, Nordin, Gunnar

“…Electronic exchange of health care data demands code/terminology systems. In the Scandinavian countries, the IFCC-IUPAC's Nomenclature for Properties and Units…”
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Abstract 3179: The head and neck cancer biomarker wiki: A tool for data mining and biomarker meta-analyses by Ceder, Rebecca, Kohonen, Pekka, Grafström, Roland C.

“…Abstract Biomarkers that accurately predict outcome or treatment response is lacking for most human tumor types, including for common and well-studied cancers…”
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Properties and units in the clinical laboratory sciences part XXIV. Properties and units in clinical molecular genetics (technical report 2017) by Petersen, Ulla M., Padró-Miquel, Ariadna, Taylor, Graham, Hertz, Jens Michael, Ceder, Rebecca, Fuentes-Arderiu, Xavier, den Dunnen, Johan T.

“…This document describes the application of the syntax, semantic rules, and format of the Nomenclature for Properties and Units (NPU) terminology for coded…”
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Arsenic alters global histone modifications in lymphocytes in vitro and in vivo by Pournara, Angeliki, Kippler, Maria, Holmlund, Teresa, Ceder, Rebecca, Grafström, Roland, Vahter, Marie, Broberg, Karin, Wallberg, Annika E.

“…Arsenic, an established carcinogen and toxicant, occurs in drinking water and food and affects millions of people worldwide. Arsenic appears to interfere with…”
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Abstract 4032: Transcriptomics analyses of normal and transformed keratinocyte lines generated novel biomarkers for prognosticating outcome in head and neck cancer by Grafstrom, Roland C., Merne, Marina, Kohonen, Pekka, Jerhammar, Fredrik, Nees, Matthias, Roberg, Karin, Ceder, Rebecca

“…Abstract We tested the hypothesis that characterization of differentiation-related features in human cell lines might reveal prognosticating genes undetected…”
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Toward the Replacement of Animal Experiments through the Bioinformatics-driven Analysis of 'Omics' Data from Human Cell Cultures by Grafström, Roland C, Nymark, Penny, Hongisto, Vesa, Spjuth, Ola, Ceder, Rebecca, Willighagen, Egon, Hardy, Barry, Kaski, Samuel, Kohonen, Pekka

“…This paper outlines the work for which Roland Grafström and Pekka Kohonen were awarded the 2014 Lush Science Prize. The research activities of the Grafström…”
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Cancer Biology, Toxicology and Alternative Methods Development Go Hand‐in‐Hand by Kohonen, Pekka, Ceder, Rebecca, Smit, Ines, Hongisto, Vesa, Myatt, Glenn, Hardy, Barry, Spjuth, Ola, Grafström, Roland

“…Toxicological research faces the challenge of integrating knowledge from diverse fields and novel technological developments generally in the biological and…”
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Formaldehyde dehydrogenase: Beyond phase I metabolism by Thompson, Chad M., Ceder, Rebecca, Grafström, Roland C.

“…Formaldehyde dehydrogenase, formally Class III alcohol dehydrogenase (ADH3), has recently been discovered to partially regulate nitrosothiol homeostasis by…”
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Differentiation-Promoting Culture of Competent and Noncompetent Keratinocytes Identifies Biomarkers for Head and Neck Cancer by Ceder, Rebecca, Haig, Ylva, Merne, Marina, Hansson, Annette, Zheng, Xi, Roberg, Karin, Nees, Matthias, Iljin, Kristiina, Bloor, Balvinder K, Morgan, Peter R, Fadeel, Bengt, Grafström, Roland C

“…Aberrant contact-inhibited proliferation and differentiation induction couple with tumor severity, albeit with an imprecise association with prognosis…”
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Abstract 2169: Integrated proteomic and genomic profiling data from a tongue squamous cell carcinoma cell line separates normal and tumor tongue tissue by Ceder, Rebecca, Staab, Claudia A., Roberg, Karin, Jörnvall, Hans, Höög, Jan-Olov, Grafström, Roland C.

“…Abstract In depth characterization of individual human tumor cell lines might serve to explore the concept of future personalized cancer management. To address…”
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Requirement of apoptotic protease-activating factor-1 for bortezomib-induced apoptosis but not for Fas-mediated apoptosis in human leukemic cells by Ottosson-Wadlund, Astrid, Ceder, Rebecca, Preta, Giulio, Pokrovskaja, Katja, Grafström, Roland C, Heyman, Mats, Söderhäll, Stefan, Grandér, Dan, Hedenfalk, Ingrid, Robertson, John D, Fadeel, Bengt

“…Bortezomib is a highly selective inhibitor of the 26S proteasome and has been approved for clinical use in the treatment of relapsing and refractory multiple…”
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Probabilistic toxicogenomics studies in vitro by Parkkinen, Juuso, Ceder, Rebecca, Willighagen, Egon, Wennerberg, Krister, Kaski, Samuel, Grafström, Roland

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Bioinformatics-based cancer research have wide toxicological applicability by Grafström, Roland C., Ceder, Rebecca, Fadeel, Bengt, Roberg, Karin, Willighagen, Egon

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Matrix metalloproteinase-7 and -13 expression associate to cisplatin resistance in head and neck cancer cell lines by Ansell, Anna, Jerhammar, Fredrik, Ceder, Rebecca, Grafström, Roland, Grénman, Reidar, Roberg, Karin

“…Summary Concomitant chemoradiotherapy is a common treatment for advanced head and neck squamous cell carcinomas (HNSCC). Cisplatin is the backbone of…”
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