Search Results - "Cecilia Subauste, M"

Vinculin Modulation of Paxillin-FAK Interactions Regulates ERK to Control Survival and Motility by Subauste, M. Cecilia, Pertz, Olivier, Adamson, Eileen D., Turner, Christopher E., Junger, Sachiko, Hahn, Klaus M.

“…Cells lacking vinculin are highly metastatic and motile. The reasons for this finding have remained unclear. Both enhanced survival and motility are critical…”
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Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling by Portillo, Jose-Andres C, Schwartz, Isaac, Zarini, Simona, Bapputty, Reena, Kern, Timothy S, Gubitosi-Klug, Rose A, Murphy, Robert C, Subauste, M Cecilia, Subauste, Carlos S

“…The cell surface receptor CD40 is required for the development of retinopathies induced by diabetes and ischemia/reperfusion. The purpose of this study was to…”
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Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems by Cecilia Subauste, M, Kupriyanova, Tatyana A, Conn, Erin M, Ardi, Veronica C, Quigley, James P, Deryugina, Elena I

“…Increased metastatic and angiogenic potentials of aggressive human colon carcinoma cells were verified in independent chick embryo models by comparing in vivo…”
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A cell‐penetrating CD40‐TRAF2,3 blocking peptide diminishes inflammation and neuronal loss after ischemia/reperfusion by Portillo, Jose‐Andres C., Yu, Jin‐Sang, Hansen, Samuel, Kern, Timothy S., Subauste, M. Cecilia, Subauste, Carlos S.

“…While the administration of anti‐CD154 mAbs in mice validated the CD40‐CD154 pathway as a target against inflammatory disorders, this approach caused…”
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Vinculin Controls PTEN Protein Level by Maintaining the Interaction of the Adherens Junction Protein β-Catenin with the Scaffolding Protein MAGI-2 by Subauste, M. Cecilia, Nalbant, Perihan, Adamson, Eileen D., Hahn, Klaus M.

“…PTEN is a frequently mutated tumor suppressor in malignancies. Interestingly, some malignancies exhibit undetectable PTEN protein without mutations or loss of…”
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CD40 and tumour necrosis factor‐α co‐operate to up‐regulate inducuble nitric oxide synthase expression in macrophages by Portillo, Jose‐Andres C., Feliciano, Luis Muniz, Okenka, Genevieve, Heinzel, Frederick, Subauste, M. Cecilia, Subauste, Carlos S.

“…Summary Regulation of inducible nitric oxide synthase (NOS2) expression is important given the role of this enzyme in inflammation, control of infections and…”
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RACK1 downregulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells by Subauste, M Cecilia, Ventura-Holman, Tereza, Du, Liqin, Subauste, Jose S, Chan, Shing-Leng, Yu, Victor C, Maher, Joseph F

“…Evasion of apoptosis plays an important role in colon cancer progression. Following loss of the Apc tumor suppressor gene in mice, the gene encoding Fem1b is…”
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Fem1b, a proapoptotic protein, mediates proteasome inhibitor-induced apoptosis of human colon cancer cells by Subauste, M. Cecilia, Sansom, Owen J., Porecha, Nehal, Raich, Natacha, Du, Liqin, Maher, Joseph F.

“…In the treatment of colon cancer, the development of resistance to apoptosis is a major factor in resistance to therapy. New molecular approaches to overcome…”
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Rho Family Proteins Modulate Rapid Apoptosis Induced by Cytotoxic T Lymphocytes and Fas by Subauste, M.Cecilia, Von Herrath, Matthias, Benard, Valerie, Chamberlain, Chester E., Chuang, Tsung-Hsien, Chu, Keting, Bokoch, Gary M., Hahn, Klaus M.

“…Little is known about the role of Rho proteins in apoptosis produced by stimuli evolved specifically to produce apoptosis, such as granzymes from cytotoxic T…”
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Fem1b antigen in the stool of ApcMin mice as a biomarker of early Wnt signaling activation in intestinal neoplasia by Subauste, M Cecilia, Ventura-Holman, Tereza, Lu, Deyin, Du, Liqin, Sansom, Owen J, Maher, Joseph F

“…Colorectal cancer is preventable by early detection and removal of precursor lesions. Central to early stages of colorectal neoplasia is activation of Wnt…”
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RACK1 down-regulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells by Subauste, M. Cecilia, Ventura-Holman, Tereza, Du, Liqin, Subauste, Jose S., Chan, Shing-Leng, Yu, Victor C., Maher, Joseph F.

“…Evasion of apoptosis plays an important role in colon cancer progression. Following loss of the Apc tumor suppressor gene in mice, the gene encoding Fem1b is…”
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A Catalytic Antibody Produces Fluorescent Tracers of Gap Junction Communication in Living Cells by Subauste, M. Cecilia, List, Benjamin, Guan, Xiaojun, Hahn, Klaus M., Lerner, Richard, Gilula, Norton B.

“…The antibody 38C2 efficiently catalyzed a retro-Michael reaction to convert a novel, cell-permeable fluorogenic substrate into fluorescein within living cells…”
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The ADP-ribosylation Factor (ARF)-related GTPase ARF-related Protein Binds to the ARF-specific Guanine Nucleotide Exchange Factor Cytohesin and Inhibits the ARF-dependent Activation of Phospholipase D by Schürmann, A, Schmidt, M, Asmus, M, Bayer, S, Fliegert, F, Koling, S, Massmann, S, Schilf, C, Subauste, M C, Voss, M, Jakobs, K H, Joost, H G

“…ADP-ribosylation factor-related protein (ARP) is a membrane-associated GTPase with remote similarity to the family of ADP-ribosylation factors (ARF). In a…”
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CD40 and tumour necrosis factor-[alpha] co-operate to up-regulate inducuble nitric oxide synthase expression in macrophages by Portillo, Jose-Andres C, Feliciano, Luis Muniz, Okenka, Genevieve, Heinzel, Frederick, Subauste, M Cecilia, Subauste, Carlos S

“…Summary Regulation of inducible nitric oxide synthase (NOS2) expression is important given the role of this enzyme in inflammation, control of infections and…”
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Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure by Subauste, M C, Jacoby, D B, Richards, S M, Proud, D

“…Rhinovirus infections cause over one third of all colds and are a contributing factor to exacerbations of asthma. To gain insights into the early biochemical…”
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Fem1b antigen in the stool of Apc Min mice as a biomarker of early Wnt signaling activation in intestinal neoplasia by Subauste, M. Cecilia, Ventura-Holman, Tereza, Lu, Deyin, Du, Liqin, Sansom, Owen J, Maher, Joseph F

“…Abstract Background : Colorectal cancer is preventable by early detection and removal of precursor lesions. Central to early stages of colorectal neoplasia is…”
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Vinculin Controls PTEN Protein Level by Maintaining the Interaction of the Adherens Junction Protein β-Catenin with the Scaffolding Protein MAGI-2 by M. Cecilia Subauste, Perihan Nalbant, Eileen D. Adamson, Klaus M. Hahn

“…PTEN is a frequently mutated tumor suppressor in malignancies. Interestingly, some malignancies exhibit undetectable PTEN protein without mutations or loss of…”
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Transient exposure of human bronchial epithelial cells to cytokines leads to persistent increased expression of ICAM-1 by Subauste, M C, Choi, D C, Proud, D

“…Effects of several cytokines on kinetics of Intercellular Adhesion Molecule-1 (ICAM-1) and Vascular Cell Adhesion Molecule-1 (VCAM-1) expression were studied…”
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Glucocorticoids do not alter peptidase expression on a human bronchial epithelial cell line by Proud, D, Subauste, M C, Ward, P E

“…Respiratory epithelial cell surface neutral endopeptidase 24.11 (NEP-24.11) degrades proinflammatory peptides, and it has been suggested that glucocorticoids…”
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