Search Results - "Ceccaldi, Alexandre"

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    Delivering the power of nanomedicine to patients today by Germain, Matthieu, Caputo, Fanny, Metcalfe, Su, Tosi, Giovanni, Spring, Kathleen, Åslund, Andreas K.O., Pottier, Agnes, Schiffelers, Raymond, Ceccaldi, Alexandre, Schmid, Ruth

    Published in Journal of controlled release (10-10-2020)
    “…The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified…”
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    Journal Article
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    Triplex Formation on DNA Targets: How To Choose the Oligonucleotide by Vekhoff, Pierre, Ceccaldi, Alexandre, Polverari, David, Pylouster, Jean, Pisano, Claudio, Arimondo, Paola B

    Published in Biochemistry (Easton) (25-11-2008)
    “…Triplex-forming oligonucleotides (TFOs) are sequence-specific DNA binders. TFOs provide a tool for controlling gene expression or, when attached to an…”
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    Copeptin as a prognostic biomarker in acute myocardial infarction by Lattuca, Benoit, Sy, Vuthy, Nguyen, Lee S., Bernard, Maguy, Zeitouni, Michel, Overtchouk, Pavel, Yan, Yan, Hammoudi, Nadjib, Ceccaldi, Alexandre, Collet, Jean-Philippe, Kerneis, Mathieu, Diallo, Abdourahmane, Montalescot, Gilles, Silvain, Johanne

    Published in International journal of cardiology (01-01-2019)
    “…Copeptin - the C-terminal section of vasopressin precursor - is a novel biomarker, that has been shown to be a useful prognostic factor in heart failure,…”
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    Journal Article
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    Altered cardiac reserve is a determinant of exercise intolerance in sickle cell anaemia patients by Hammoudi, Nadjib, Ceccaldi, Alexandre, Haymann, Jean‐Philippe, Guedeney, Paul, Nicolas‐Jilwan, Fadila, Zeitouni, Michel, Montalescot, Gilles, Lionnet, François, Isnard, Richard, Hatem, Stéphane N.

    Published in European journal of clinical investigation (01-01-2022)
    “…Background The underlying mechanisms of exercise intolerance in sickle cell anaemia (SCA) patients are complex and not yet completely understood. While latent…”
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    Cardiac manifestations in sickle cell disease varies with patient genotype by Guedeney, Paul, Lionnet, François, Ceccaldi, Alexandre, Stankovic Stojanovic, Katia, Cohen, Ariel, Mattioni, Sarah, Montalescot, Gilles, Bachmeyer, Claude, Isnard, Richard, Haymann, Jean‐Philippe, Hammoudi, Nadjib

    Published in British journal of haematology (01-06-2018)
    “…Summary Cardiac involvement is well characterized in sickle cell anaemia (SCA) but cardiac features associated with Haemoglobin SC (HbSC) disease are mostly…”
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    DNA methylation associated with polycomb repression in retinoic acid receptor β silencing by Moison, Céline, Senamaud‐Beaufort, Catherine, Fourrière, Lou, Champion, Christine, Ceccaldi, Alexandre, Lacomme, Stéphanie, Daunay, Antoine, Tost, Jörg, Arimondo, Paola B., Guieysse‐Peugeot, Anne‐Laure

    Published in The FASEB journal (01-04-2013)
    “…Retinoic acid receptor β 2 (RARβ2) is a tumor suppressor gene whose loss of expression is recurrent in prostate cancers. Here we studied the epigenetic…”
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    Identification of Novel Inhibitors of DNA Methylation by Screening of a Chemical Library by Ceccaldi, Alexandre, Rajavelu, Arumugam, Ragozin, Sergey, Sénamaud-Beaufort, Catherine, Bashtrykov, Pavel, Testa, Noé, Dali-Ali, Hana, Maulay-Bailly, Christine, Amand, Séverine, Guianvarc’h, Dominique, Jeltsch, Albert, Arimondo, Paola B

    Published in ACS chemical biology (15-03-2013)
    “…In order to discover new inhibitors of the DNA methyltransferase 3A/3L complex, we used a medium-throughput nonradioactive screen on a random collection of…”
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    Journal Article
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    DNA methyltransferase assays by Jurkowska, Renata Z, Ceccaldi, Alexandre, Zhang, Yingying, Arimondo, Paola B, Jeltsch, Albert

    “…DNA methyltransferases are important enzymes and their inhibition has many potential applications. The investigation of DNA methyltransferases as well as…”
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    Journal Article
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    Triple Helix-Forming Oligonucleotides Conjugated to New Inhibitors of Topoisomerase II:  Synthesis and Binding Properties by Duca, Maria, Oussedik, Kahina, Ceccaldi, Alexandre, Halby, Ludovic, Guianvarc'h, Dominique, Dauzonne, Daniel, Monneret, Claude, Sun, Jian-Sheng, Arimondo, Paola B

    Published in Bioconjugate chemistry (01-07-2005)
    “…Triplex-forming oligonucleotides (TFOs) are among the most specific DNA ligands and represent an important tool for specific regulation of gene expression…”
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