Search Results - "Ceballos, Nora R."
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Functional studies of p.R132C, p.R149C, p.M283V, p.E431K, and a novel c.652-2A>G mutations of the CYP21A2 gene
Published in PloS one (25-03-2014)“…Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is the most frequent inborn error of metabolism and accounts for 90-95% of CAH cases. In…”
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2
Mechanism of hCG-induced spermiation in the toad Rhinella arenarum (Amphibia, Anura)
Published in General and comparative endocrinology (01-12-2010)“…Research highlights ► Spermiation is not induced by inhibiting the Na+ /K+ ATPase in the absence of hCG. ► Ouabain inhibits hCG-induced spermiation but not…”
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3
Melatonin Inhibits Glucocorticoid Receptor Nuclear Translocation in Mouse Thymocytes
Published in Endocrinology (Philadelphia) (01-11-2006)“…The antiapoptotic effect of melatonin (MEL) has been described in several systems. In particular, MEL inhibits glucocorticoid-mediated apoptosis. Our group…”
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4
Characterization and seasonal changes in LHβ and FSHβ mRNA of Rhinella arenarum (Amphibia, Anura)
Published in General and comparative endocrinology (15-06-2013)“…Highlights • Tetrapods studied conserve 12 cysteins and 1 (LH) or 2 (FSH) N-Glycosilation sites. • LHβ and FSHβ have three peaks along the year, in spring,…”
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Journal Article -
5
Overcrowding-mediated stress alters cell proliferation in key neuroendocrine areas during larval development in Rhinella arenarum
Published in Journal of experimental zoology. Part A, Ecological and integrative physiology (01-02-2016)“…ABSTRACT Exposure to adverse environmental conditions can elicit a stress response, which results in an increase in endogenous corticosterone levels. In early…”
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6
5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura)
Published in General and comparative endocrinology (01-05-2012)“…Abstract The reduction of A-ring of glucocorticoids to produce 5α-dihydro-derivatives by 5α-reductases has been considered as a pathway of irreversible…”
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7
New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects
Published in The Journal of steroid biochemistry and molecular biology (01-02-2009)“…Antiglucocorticoids that act as antagonists at the glucocorticoid receptor (GR) level may be used to block or modulate the undesirable effects of…”
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8
Metabolic and endocrine changes during the reproductive cycle of dermatophagic caecilians in captivity
Published in Zoology (Jena) (01-10-2013)“…The amphibian order Gymnophiona is poorly known, and studies about their reproduction are mainly comparative and descriptive, focusing on the structure of…”
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9
Cytosolic glucocorticoid receptor in the testis of Bufo arenarum: Seasonal changes in its binding parameters
Published in General and comparative endocrinology (01-07-2006)“…Glucocorticoids (GC) are the hormonal mediators of stress. In mammals, high levels of GC have negative effects on reproductive physiology. For instance, GC can…”
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10
Hexachlorobenzene as hormonal disruptor—studies about glucocorticoids: Their hepatic receptors, adrenal synthesis and plasma levels in relation to impaired gluconeogenesis
Published in Biochemical pharmacology (15-03-2007)“…In Wistar rats, hexachlorobenzene (HCB) depresses the gluconeogenic enzyme phosphoenolpyruvate-carboxykinase (PEPCK). In the liver, glucocorticoids (GC)…”
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11
Relationship between steroidogenesis and spermiation in Rana catesbeiana and Leptodactylus ocellatus
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (01-08-2006)“…The present study employs an in vitro system to analyse the role of steroid hormones in hCG-induced spermiation in two species of anuran amphibian: Rana…”
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Journal Article -
12
Seasonal Changes in the Activity of 11β-Hydroxysteroid Dehydrogenase in Toad Testes
Published in Annals of the New York Academy of Sciences (01-04-2005)“…: In mammals, glucocorticoids (GC) are inactivated by the oxidative activity of 11β‐hydroxysteroid dehydrogenase (11β‐HSD). To study that mechanism in the…”
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13
Synthesis of 6,19-cyclopregnanes. Constrained analogues of steroid hormones
Published in Organic & biomolecular chemistry (01-01-2007)“…A procedure for the synthesis of 6,19-cyclopregnanes is described involving an intramolecular alkylation reaction of Delta(4)-3-keto steroids with a…”
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14
Steroid production in toads
Published in Journal of steroid biochemistry and molecular biology (01-06-2003)“…In Bufo arenarum, androgen biosynthesis occurs through a complete 5-ene pathway, including 5-androstane-3β,17β-diol as the immediate precursor of testosterone…”
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Journal Article Conference Proceeding -
15
Effects of mGnRH on testicular steroidogenesis in the toad Bufo arenarum
Published in General and comparative endocrinology (15-06-2002)“…GnRH controls vertebrate reproduction in several ways. This hormone not only affects the secretion of gonadotropins from the pituitary gland but also has a…”
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16
Effect of Salt Acclimatization on 3β-Hydroxysteroid Dehydrogenase/Isomerase Activity in the Interrenal of Bufo arenarum
Published in General and comparative endocrinology (01-03-2002)“…In amphibians, aldosterone (Aldo) is particularly important in the regulation of Na+ exchange by skin and urinary bladder. In previous works we studied a key…”
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Journal Article -
17
Kinetic properties of microsomal 3β hydroxysteroid dehydrogenase-isomerase from the testis of Bufo arenarum H
Published in The Journal of steroid biochemistry and molecular biology (2000)“…3β-hydroxysteroid dehydrogenase 5-ene isomerase (3βHSD/I) activity is necessary for the biosynthesis of hormonally active steroids. A dual distribution of the…”
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Journal Article -
18
Functional Studies of p.R132C, p.R149C, p.M283V, p.E431K, and a Novel c.652-2AG Mutations of the CYP21A2 Gene
Published in PloS one (25-03-2014)“…Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is the most frequent inborn error of metabolism and accounts for 90-95% of CAH cases. In…”
Get full text
Journal Article -
19
Overcrowding-mediated stress alters cell proliferation in key neuroendocrine areas during larval development in Rhinella arenarum: OVERCROWDING-MEDIATED STRESS IN AMPHIBIAN LARVAE
Published in Journal of experimental zoology. Part A, Ecological genetics and physiology (01-02-2016)Get full text
Journal Article -
20
11β-Hydroxysteroid dehydrogenase in the testis of Bufo arenarum: Changes in its seasonal activity
Published in General and comparative endocrinology (01-09-2005)“…In rat Leydig cells, glucocorticoids (GC) inhibit testosterone (T) synthesis via glucocorticoid receptor (GR). However, GC access to GR is regulated by the…”
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