Search Results - "Ceballos, María Paula"
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Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines
Published in Toxicology letters (01-06-2018)“…•Cambinol and EX-527 reduced cell survival and migration.•SIRTs 1 and 2 inhibitors increased apoptosis.•Cambinol and EX-527 modulated P-gp and MRP3 expression…”
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Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity
Published in PloS one (17-03-2015)“…Hepatocellular carcinoma (HCC) is the fifth most frequent cancer worldwide. Sorafenib is the only drug available that improves the overall survival of HCC…”
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3
Participation of 5-lipoxygenase and LTB4 in liver regeneration after partial hepatectomy
Published in Scientific reports (03-12-2019)“…Regeneration is the unmatched liver ability for recovering its functional mass after tissue lost. Leukotrienes (LT) are a family of eicosanoids with the…”
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Sirtuin 1 and 2 inhibitors enhance the inhibitory effect of sorafenib in hepatocellular carcinoma cells
Published in European journal of pharmacology (05-02-2021)“…Multidrug resistance (MDR) counteracts the efficiency of sorafenib, an important first-line therapy for hepatocellular carcinoma (HCC). Sirtuins (SIRTs) 1 and…”
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Delta-tocotrienol enhances the anti-tumor effects of interferon alpha through reactive oxygen species and Erk/MAPK signaling pathways in hepatocellular carcinoma cells
Published in Canadian journal of physiology and pharmacology (01-05-2022)“…The complexity of hepatocellular carcinoma (HCC) signaling and the failure of pharmacological therapeutics reveal the significance of establishing new…”
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Quercetin prevents liver carcinogenesis by inducing cell cycle arrest, decreasing cell proliferation and enhancing apoptosis
Published in Molecular nutrition & food research (01-02-2014)“…SCOPE: Quercetin is the most abundant flavonoid in human diet. It has special interest as it holds anticancerous properties. This study aims to clarify the…”
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Extracellular Vesicles and Cancer Multidrug Resistance: Undesirable Intercellular Messengers?
Published in Life (Basel, Switzerland) (01-07-2023)“…Cancer multidrug resistance (MDR) is one of the main mechanisms contributing to therapy failure and mortality. Overexpression of drug transporters of the ABC…”
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Interferon-α2b and transforming growth factor-β1 treatments on HCC cell lines: Are Wnt/β-catenin pathway and Smads signaling connected in hepatocellular carcinoma?
Published in Biochemical pharmacology (01-12-2011)“…Wnt/β-catenin pathway is often dysregulated in hepatocellular carcinoma (HCC). Activated β-catenin accumulates in the cytosol and nucleus and forms a nuclear…”
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FoxO3a nuclear localization and its association with β-catenin and Smads in IFN-α-treated hepatocellular carcinoma cell lines
Published in Journal of interferon & cytokine research (01-11-2014)“…Interferon-α2b (IFN-α2b) reduces proliferation and increases apoptosis in hepatocellular carcinoma cells by decreasing β-catenin/TCF4/Smads interaction…”
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Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives
Published in Biochemical pharmacology (01-06-2023)“…[Display omitted] Hepatocellular carcinoma (HCC) is the third most common cause of death from cancer worldwide. Therapeutic strategies are still challenging…”
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Role of the RNA binding protein IGF2BP1 in cancer multidrug resistance
Published in Biochemical pharmacology (01-12-2024)“…[Display omitted] The insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1), a member of a conserved family of single-stranded RNA-binding proteins…”
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Relationship between genotoxic effects of breast cancer treatments and patient basal DNA integrity
Published in Journal of environmental pathology, toxicology and oncology (2014)“…Radiotherapy and chemotherapy cause genotoxic side effects that are highly variable among patients. In this study, we evaluated DNA integrity using the comet…”
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Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet
Published in The Journal of nutritional biochemistry (01-08-2018)“…Obesity is accompanied by a low-grade inflammation state, characterized by increased proinflammatory cytokines levels such as tumor necrosis factor alpha…”
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Mammaglobin A: review and clinical utility
Published in Advances in clinical chemistry (2014)“…Mammaglobin A is a protein that belongs to the secretoglobin superfamily. It has highly specific expression in cells from most breast cancers and may be used…”
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Mammaglobin A
Published in Advances in Clinical Chemistry (2014)“…Mammaglobin A is a protein that belongs to the secretoglobin superfamily. It has highly specific expression in cells from most breast cancers and may be used…”
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