Search Results - "Cazier, J. B."

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification by Edginton-White, B., Maytum, A., Kellaway, S. G., Goode, D. K., Keane, P., Pagnuco, I., Assi, S. A., Ames, L., Clarke, M., Cockerill, P. N., Göttgens, B., Cazier, J. B., Bonifer, C.

“…Developmental control of gene expression critically depends on distal cis-regulatory elements including enhancers which interact with promoters to activate…”
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Technical and implementation issues in using next-generation sequencing of cancers in clinical practice by Ulahannan, D, Kovac, M B, Mulholland, P J, Cazier, J-B, Tomlinson, I

“…Next-generation sequencing (NGS) of cancer genomes promises to revolutionise oncology, with the ability to design and use targeted drugs, to predict outcome…”
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Coronavirus Disease 2019: the Pivotal Role of UK Clinical Oncology and the UK Coronavirus Cancer Monitoring Project by Best, J., Starkey, T., Chatterjee, A., Fackrell, D., Pettit, L., Srihari, N., Tween, H., Olsson-Brown, A., Cheng, V., Hughes, D.J., Lee, A.J.X., Purshouse, K., Arnold, R., UK Coronavirus Cancer Monitoring Project Team, Sivakumar, S., Cazier, J.-B., Lee, L.Y.W.

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Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia by Knight, S J L, Yau, C, Clifford, R, Timbs, A T, Sadighi Akha, E, Dréau, H M, Burns, A, Ciria, C, Oscier, D G, Pettitt, A R, Dutton, S, Holmes, C C, Taylor, J, Cazier, J-B, Schuh, A

“…Genome-wide array approaches and sequencing analyses are powerful tools for identifying genetic aberrations in cancers, including leukemias and lymphomas…”
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Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma by MacGregor, T. P., Carter, R., Gillies, R. S., Findlay, J. M., Kartsonaki, C., Castro-Giner, F., Sahgal, N., Wang, L. M., Chetty, R., Maynard, N. D., Cazier, J. B., Buffa, F., McHugh, P. J., Tomlinson, I., Middleton, M. R., Sharma, R. A.

“…Oxaliplatin-based chemotherapy is used to treat patients with esophageal adenocarcinoma (EAC), but no biomarkers are currently available for patient selection…”
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Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden by Cazier, J -b, Rao, S R, Mclean, C M, Walker, A K, Wright, B J, Jaeger, E E M, Kartsonaki, C, Marsden, L, Yau, C, Camps, C, Kaisaki, P, Taylor, J, Catto, J W, Tomlinson, I P M, Kiltie, A E, Hamdy, F C

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High-resolution genomic profiling of human papillomavirus-associated vulval neoplasia by Purdie, K J, Harwood, C A, Gibbon, K, Chaplin, T, Young, B D, Cazier, J B, Singh, N, Leigh, I M, Proby, C M

“…Background: The incidence of human papillomavirus-associated vulval neoplasia is increasing worldwide; yet the associated genetic changes remain poorly…”
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A genome-wide association study on copy-number variation identifies a 11q11 loss as a candidate susceptibility variant for colorectal cancer by Fernandez-Rozadilla, C., Cazier, J. B., Tomlinson, I., Brea-Fernández, A., Lamas, M. J., Baiget, M., López-Fernández, L. A., Clofent, J., Bujanda, L., Gonzalez, D., de Castro, L., Hemminki, K., Bessa, X., Andreu, M., Jover, R., Xicola, R., Llor, X., Moreno, V., Castells, A., Castellví-Bel, S., Carracedo, A., Ruiz-Ponte, C.

“…Colorectal cancer (CRC) is a complex disease, and therefore its development is determined by the combination of both environmental factors and genetic…”
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Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration by Fernandez-Rozadilla, C, Cazier, J B, Moreno, V, Crous-Bou, M, Guinó, E, Durán, G, Lamas, M J, López, R, Candamio, S, Gallardo, E, Paré, L, Baiget, M, Páez, D, López-Fernández, L A, Cortejoso, L, García, M I, Bujanda, L, González, D, Gonzalo, V, Rodrigo, L, Reñé, J M, Jover, R, Brea-Fernández, A, Andreu, M, Bessa, X, Llor, X, Xicola, R, Palles, C, Tomlinson, I, Castellví-Bel, S, Castells, A, Ruiz-Ponte, C, Carracedo, A

“…The development of genotyping technologies has allowed for wider screening for inherited causes of variable outcomes following drug administration. We have…”
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Linkage of osteoporosis to chromosome 20p12 and association to BMP2 by Styrkarsdottir, Unnur, Cazier, Jean-Baptiste, Kong, Augustine, Rolfsson, Ottar, Larsen, Helene, Bjarnadottir, Emma, Johannsdottir, Vala D, Sigurdardottir, Margret S, Bagger, Yu, Christiansen, Claus, Reynisdottir, Inga, Grant, Struan F A, Jonasson, Kristjan, Frigge, Michael L, Gulcher, Jeffrey R, Sigurdsson, Gunnar, Stefansson, Kari

“…Osteoporotic fractures are a major cause of morbidity and mortality in ageing populations. Osteoporosis, defined as low bone mineral density (BMD) and…”
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1677MO COVID-19 mortality in hospitalized cancer patients is not significantly affected by chemotherapy or other anti-cancer treatments by Lee, L., Starkey, T., Cazier, J-B., Kerr, R., Middleton, G.

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1703P UK Coronavirus Cancer Monitoring Project (UKCCMP): A national reporting network for real time data of the COVID-19 pandemic by Olsson-Brown, A.C., Hughes, D.J., Purshouse, K., Lee, L., Cheng, V.W., Lee, A.J.X., Protheroe, E., Smith, A., Curley, H., Arnold, R., Cazier, J-B., D'Costa, J., Palles, C., Campton, N., Varnai, C., Sivakumar, S., Kerr, R., Middleton, G.

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Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden by Cazier, J. -B., Rao, S. R., McLean, C. M., Walker, A. K., Wright, B. J., Jaeger, E. E. M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J. W., Tomlinson, I. P. M., Kiltie, A. E., Hamdy, F. C.

“…Bladder cancers are a leading cause of death from malignancy. Molecular markers might predict disease progression and behaviour more accurately than the…”
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EPIDERMIS INFLUENCE ON THE GAS EXCHANGES AROUND A PRODUCE by Cazier, J. B., Gekas, V., Nilsson, T.

“…The exponential decay of water loss with time from freshly harvested has been confronted to various mathematical models of the interaction between air humidity…”
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Correction: Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden by Cazier, J. -B., Rao, S. R., McLean, C. M., Walker, A. K., Wright, B. J., Jaeger, E. E. M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J. W., Tomlinson, I. P. M., Kiltie, A. E., Hamdy, F. C.

“…Nature Communications 5: Article number: 3756 (2014); Published: 29 April 2014; Updated: 26 June 2014; Updated: 10 October 2014. In the original version of…”
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Correction: Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden by Cazier, J. -B., Rao, S. R., McLean, C. M., Walker, A. K., Wright, B. J., Jaeger, E. E. M., Kartsonaki, C., Marsden, L., Yau, C., Camps, C., Kaisaki, P., Taylor, J., Catto, J. W., Tomlinson, I. P. M., Kiltie, A. E., Hamdy, F. C.

“…Nature Communications 5: Article number: 3756 (2014); Published: 29 April 2014; Updated: 26 June 2014; Updated: 10 October 2014. The financial support for this…”
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A common inversion under selection in Europeans by Kong, Augustine, Stefansson, Kari, Stefansson, Hreinn, Helgason, Agnar, Thorleifsson, Gudmar, Steinthorsdottir, Valgerdur, Masson, Gisli, Barnard, John, Baker, Adam, Jonasdottir, Aslaug, Ingason, Andres, Gudnadottir, Vala G, Desnica, Natasa, Hicks, Andrew, Gylfason, Arnaldur, Gudbjartsson, Daniel F, Jonsdottir, Gudrun M, Sainz, Jesus, Agnarsson, Kari, Birgisdottir, Birgitta, Ghosh, Shyamali, Olafsdottir, Adalheidur, Cazier, Jean-Baptiste, Kristjansson, Kristleifur, Frigge, Michael L, Thorgeirsson, Thorgeir E, Gulcher, Jeffrey R

“…A refined physical map of chromosome 17q21.31 uncovered a 900-kb inversion polymorphism. Chromosomes with the inverted segment in different orientations…”
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Corrigendum: Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden by Cazier, J -b, Rao, S R, Mclean, C M, Walker, A L, Wright, B J, Jaeger, E E M, Kartsonaki, C, Marsden, L, Yau, C, Camps, C, Kaisaki, P, Taylor, J, Catto, J W, Tomlinson, I P M, Kiltie, A E, Hamdy, F C

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WATER ACTIVITY AND ITS PREDICTION: A REVIEW by Cazier, Jean-Baptiste, Gekas, Vassilis

“…Water activity is a very useful parameter in food preservation. Raoult's law gave a first base in the case of ideal solutions. In 1966, Norrish presented a…”
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