Search Results - "Cayabyab, Mark"

Assessment of SARS‐CoV‐2 entry in gingival epithelial cells expressing CD147 by Bontempo, Alexander, Chirino, Alexandra, Heidari, Alireza, Boparai, Saurav, Arora, Saher, Ruiz, Sunniva, Antonson, Sibel A., Kawai, Toshihisa, Cayabyab, Mark J.

“…SARS‐CoV‐2, the causative agent of the debilitating COVID‐19, is mainly transmitted by first infecting nose and lung epithelial cells. The mouth is also…”
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Oral Delivery of a Novel Recombinant Streptococcus mitis Vector Elicits Robust Vaccine Antigen-Specific Oral Mucosal and Systemic Antibody Responses and T Cell Tolerance by Xie, Emily, Kotha, Abhiroop, Biaco, Tracy, Sedani, Nikita, Zou, Jonathan, Stashenko, Phillip, Duncan, Margaret J, Campos-Neto, Antonio, Cayabyab, Mark J

“…The pioneer human oral commensal bacterium Streptococcus mitis has unique biologic features that make it an attractive mucosal vaccine or therapeutic delivery…”
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Inhibition of SARS-CoV-2 infection by Porphyromonas gingivalis and the oral microbiome by Bontempo, Alexander, Chirino, Alexandra, Heidari, Alireza, Lugo, Alexandra, Shindo, Satoru, Pastore, Maria R, Madonia, Riccardo, Antonson, Sibel A, Godoy, Cristina, Nichols, Frank C, Potempa, Jan, Davey, Mary Ellen, Kawai, Toshihisa, Cayabyab, Mark J

“…The COVID-19 pandemic persists despite the availability of vaccines, and it is, therefore, crucial to develop new therapeutic and preventive approaches. In…”
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Correction: Oral Delivery of a Novel Recombinant Streptococcus mitis Vector Elicits Robust Vaccine Antigen-Specific Oral Mucosal and Systemic Antibody Responses and T Cell Tolerance by Xie, Emily, Kotha, Abhiroop, Biaco, Tracy, Sedani, Nikita, Zou, Jonathan, Stashenko, Phillip, Duncan, Margaret J, Campos-Neto, Antonio, Cayabyab, Mark J

“…(A) The signal peptide has an amino-terminal region (N), a hydrophobic core (H), a signal peptidase cleavage site (C), and an accessory Sec transport motif…”
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Commensal Streptococcus mitis is a unique vector for oral mucosal vaccination by Daifalla, Nada, Cayabyab, Mark J., Xie, Emily, Kim, Hyeun Bum, Tzipori, Saul, Stashenko, Philip, Duncan, Margaret, Campos-Neto, Antonio

“…The development of vaccine approaches that induce mucosal and systemic immune responses is critical for the effective prevention of several infections. Here,…”
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Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry by Farzan, Michael, Mirzabekov, Tajib, Kolchinsky, Peter, Wyatt, Richard, Cayabyab, Mark, Gerard, Norma P, Gerard, Craig, Sodroski, Joseph, Choe, Hyeryun

“…Chemokine receptors and related seven-transmembrane-segment (7TMS) receptors serve as coreceptors for entry of human and simian immunodeficiency viruses…”
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Robust immune response elicited by a novel and unique Mycobacterium tuberculosis protein using an optimized DNA/protein heterologous prime/boost protocol by Cayabyab, Mark J., Kashino, Suely S., Campos‐Neto, Antonio

“…Summary An efficacious tuberculosis (TB) vaccine will probably need to induce both CD4 and CD8 T‐cell responses specific to a protective Mycobacterium…”
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Recombinant Mycobacterium bovis BCG Prime-Recombinant Adenovirus Boost Vaccination in Rhesus Monkeys Elicits Robust Polyfunctional Simian Immunodeficiency Virus-Specific T-Cell Responses by Cayabyab, Mark J., Korioth-Schmitz, Birgit, Sun, Yue, Carville, Angela, Balachandran, Harikrishnan, Miura, Ayako, Carlson, Kevin R., Buzby, Adam P., Haynes, Barton F., Jacobs, William R., Letvin, Norman L.

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An unbiased peptide-wide discovery approach to select Mycobacterium tuberculosis antigens that target CD8+ T cell response during infection by Cayabyab, Mark J, Qin, Lizeng, Kashino, Suely S, Izzo, Angelo, Campos-Neto, Antonio

“…Highlights • We describe a direct approach to discover MHC Class I associate peptides of Mtb. • Prime/boost immunization induced strong CD8+ T cell response to…”
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Current and novel approaches to vaccine development against tuberculosis by Cayabyab, Mark J, Macovei, Lilia, Campos-Neto, Antonio

“…Antibiotics and vaccines are the two most successful medical countermeasures that humans have created against a number of pathogens. However a select few e.g.,…”
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Duration of Antigen Expression In Vivo following DNA Immunization Modifies the Magnitude, Contraction, and Secondary Responses of CD8+ T Lymphocytes by Hovav, Avi-Hai, Panas, Michael W, Rahman, Shaila, Sircar, Piya, Gillard, Geoffrey, Cayabyab, Mark J, Letvin, Norman L

“…The duration of Ag expression in vivo has been reported to have a minimal impact on both the magnitude and kinetics of contraction of a pathogen-induced CD8(+)…”
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Increased CCR5 Affinity and Reduced CCR5/CD4 Dependence of a Neurovirulent Primary Human Immunodeficiency Virus Type 1 Isolate by Gorry, Paul R, Taylor, Joann, Holm, Geoffrey H, Mehle, Andrew, Morgan, Tom, Cayabyab, Mark, Farzan, Michael, Wang, Hui, Bell, Jeanne E, Kunstman, Kevin, Moore, John P, Wolinsky, Steven M, Gabuzda, Dana

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Generation of CD8+ T-Cell Responses by a Recombinant Nonpathogenic Mycobacterium smegmatis Vaccine Vector Expressing Human Immunodeficiency Virus Type 1 Env by CAYABYAB, Mark J, HOVAV, Avi-Hai, HSU, Tsungda, KRIVULKA, Georgia R, LIFTON, Michelle A, GORGONE, Darci A, FENNELLY, Glenn J, HAYNES, Barton F, JACOBS, William R, LETVIN, Norman L

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The Impact of a Boosting Immunogen on the Differentiation of Secondary Memory CD8+ T Cells by HOVAV, Avi-Hai, PANAS, Michael W, OSUNA, Christa E, CAYABYAB, Mark J, AUTISSIER, Patrick, LETVIN, Norman L

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Effects of Type I Interferons on the Adjuvant Properties of Plasmid Granulocyte-Macrophage Colony-Stimulating Factor In Vivo by LIZENG QIN, GREENLAND, John R, MORIYA, Chikaya, CAYABYAB, Mark J, LETVIN, Norman L

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Adaptation of a CCR5-Using, Primary Human Immunodeficiency Virus Type 1 Isolate for CD4-Independent Replication by Kolchinsky, P, Mirzabekov, T, Farzan, M, Kiprilov, E, Cayabyab, M, Mooney, L J, Choe, H, Sodroski, J

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Rapid Memory CD8+ T-Lymphocyte Induction through Priming with Recombinant Mycobacterium smegmatis by HOVAV, Avi-Hai, CAYABYAB, Mark J, PANAS, Michael W, SANTRA, Sampa, GREENLAND, John, GEIBEN, Ralf, HAYNES, Barton F, JACOBS, William R, LETVIN, Norman L

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The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1 by Choe, H, Farzan, M, Konkel, M, Martin, K, Sun, Y, Marcon, L, Cayabyab, M, Berman, M, Dorf, M E, Gerard, N, Gerard, C, Sodroski, J

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Exploring the Stereochemistry of CXCR4-Peptide Recognition and Inhibiting HIV-1 Entry with d-Peptides Derived from Chemokines by Zhou, Naiming, Luo, Zhaowen, Luo, Jiansong, Fan, Xuejun, Cayabyab, Mark, Hiraoka, Megumi, Liu, Dongxiang, Han, Xiaobing, Pesavento, James, Dong, Chang-Zhi, Wang, Youli, An, Jing, Kaji, Hideko, Sodroski, Joseph G., Huang, Ziwei

“…Chemokine receptor CXCR4 plays an important role in the immune system and the cellular entry of human immunodeficiency virus type 1 (HIV-1). To probe the…”
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Smart Traffic Management using Convolutional Neural Networks by Escobanez, John Clement S., Cayabyab, Mark James G., Angeles-Crystal, Julie Anne

“…In cities worldwide, escalating traffic congestion due to surging populations and vehicles presents a critical challenge, causing delays, stress, increased…”
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