Search Results - "Cawthraw, Saira"

Experimental transmission of ovine atypical scrapie to cattle by Konold, Timm, Spiropoulos, John, Hills, Janet, Abdul, Hasina, Cawthraw, Saira, Phelan, Laura, McKenna, Amy, Read, Lauren, Canoyra, Sara, Marín-Moreno, Alba, Torres, Juan María

“…Classical bovine spongiform encephalopathy (BSE) in cattle was caused by the recycling and feeding of meat and bone meal contaminated with a transmissible…”
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Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges by Konold, Timm, Bone, Gemma E, Clifford, Derek, Chaplin, Melanie J, Cawthraw, Saira, Stack, Michael J, Simmons, Marion M

“…The majority of atypical bovine spongiform encephalopathy (BSE) cases so far identified worldwide have been detected by active surveillance. Consequently the…”
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Codon 141 polymorphisms of the ovine prion protein gene affect the phenotype of classical scrapie transmitted from goats to sheep by Konold, Timm, Phelan, Laura J, Donnachie, Ben R, Chaplin, Melanie J, Cawthraw, Saira, González, Lorenzo

“…A study to investigate transmission of classical scrapie via goat milk was carried out in sheep: firstly, lambs were challenged orally with goat scrapie brain…”
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Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle - an update by Konold, Timm, Arnold, Mark E, Austin, Anthony R, Cawthraw, Saira, Hawkins, Steve A C, Stack, Michael J, Simmons, Marion M, Sayers, A Robin, Dawson, Michael, Wilesmith, John W, Wells, Gerald A H

“…To provide information on dose-response and aid in modelling the exposure dynamics of the BSE epidemic in the United Kingdom groups of cattle were exposed…”
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Use of Murine Bioassay to Resolve Ovine Transmissible Spongiform Encephalopathy Cases Showing a Bovine Spongiform Encephalopathy Molecular Profile by Beck, Katy E., Sallis, Rosemary E., Lockey, Richard, Vickery, Christopher M., Béringue, Vincent, Laude, Hubert, Holder, Thomas M., Thorne, Leigh, Terry, Linda A., Tout, Anna C., Jayasena, Dhanushka, Griffiths, Peter C., Cawthraw, Saira, Ellis, Richard, Balkema-Buschmann, Anne, Groschup, Martin H., Simmons, Marion M., Spiropoulos, John

“…Two cases of unusual transmissible spongiform encephalopathy (TSE) were diagnosed on the same farm in ARQ/ARQ PrP sheep showing attributes of both bovine…”
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Abnormalities in Brainstem Auditory Evoked Potentials in Sheep with Transmissible Spongiform Encephalopathies and Lack of a Clear Pathological Relationship by Konold, Timm, Phelan, Laura J, Cawthraw, Saira, Simmons, Marion M, Chaplin, Melanie J, González, Lorenzo

“…Scrapie is transmissible spongiform encephalopathy (TSE), which causes neurological signs in sheep, but confirmatory diagnosis is usually made postmortem on…”
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retrospective immunohistochemical study reveals atypical scrapie has existed in the United Kingdom since at least 1987 by Webb, Paul R, Powell, Linda, Denyer, Margaret, Marsh, Sarah, Weaver, Colin, Simmons, Marion M, Johns, Elizabeth, Sheehan, John, Horsfield, Peter, Lyth, Chris, Wilson, Christina, Long, Ann, Cawthraw, Saira, Saunders, Ginny C, Spencer, Yvonne I

“…Correspondence: 1 Corresponding Author: Paul R. Webb, Department of Pathology, Veterinary Laboratories Agency–Weybridge, Woodham Lane, New Haw, Addlestone,…”
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Monitoring of clinical signs in goats with transmissible spongiform encephalopathies by Konold, Timm, Bone, Gemma E, Phelan, Laura J, Simmons, Marion M, González, Lorenzo, Sisó, Sílvia, Goldmann, Wilfred, Cawthraw, Saira, Hawkins, Steve A C

“…As there is limited information about the clinical signs of BSE and scrapie in goats, studies were conducted to describe the clinical progression of scrapie…”
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Clinical findings in two cases of atypical scrapie in sheep: a case report by Konold, Timm, Davis, Andrew, Bone, Gemma, Bracegirdle, John, Everitt, Sharon, Chaplin, Melanie, Saunders, Ginny C, Cawthraw, Saira, Simmons, Marion M

“…Atypical scrapie is a recently recognised form of transmissible spongiform encephalopathy of sheep that differs from classical scrapie in its neuropathological…”
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Preliminary optimisation of a simplified sample preparation method to permit direct detection of SARS-CoV-2 within saliva samples using reverse-transcription loop-mediated isothermal amplification (RT-LAMP) by Howson, Emma L.A., Kidd, Stephen P., Armson, Bryony, Goring, Alice, Sawyer, Jason, Cassar, Claire, Cross, David, Lewis, Tom, Hockey, Jess, Rivers, Samantha, Cawthraw, Saira, Banyard, Ashley, Anderson, Paul, Rahou, Sabah, Andreou, Michael, Morant, Nick, Clark, Duncan, Walsh, Charlotte, Laxman, Shailen, Houghton, Rebecca, Slater-Jefferies, Joanne, Costello, Paula, Brown, Ian, Cortes, Nicholas, Godfrey, Keith M., Fowler, Veronica L.

“…We describe the optimisation of a simplified sample preparation method which permits rapid and direct detection of SARS-CoV-2 RNA within saliva, using…”
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Real-time PCR detection and identification of prohibited mammalian and avian material in animal feeds by Cawthraw, Saira, Saunders, Ginny C, Martin, Trevor C, Sawyer, Jason, Windl, Otto, Reaney, Scott D

“…A method for the detection and identification of "prohibited" mammalian or avian material in animal feed was developed and assessed through the analysis of…”
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pathological and molecular but not clinical phenotypes are maintained after second passage of experimental atypical bovine spongiform encephalopathy in cattle by Konold, Timm, Phelan, Laura J, Clifford, Derek, Chaplin, Melanie J, Cawthraw, Saira, Stack, Michael J, Simmons, Marion M

“…BACKGROUND: Atypical bovine spongiform encephalopathies (BSEs), classified as H-type and L-type BSE based on the Western immunoblot profiles, are naturally…”
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Further characterisation of transmissible spongiform encephalopathy phenotypes after inoculation of cattle with two temporally separated sources of sheep scrapie from Great Britain by Konold, Timm, Nonno, Romolo, Spiropoulos, John, Chaplin, Melanie J, Stack, Michael J, Hawkins, Steve A C, Cawthraw, Saira, Wilesmith, John W, Wells, Gerald A H, Agrimi, Umberto, Di Bari, Michele A, Andréoletti, Olivier, Espinosa, Juan C, Aguilar-Calvo, Patricia, Torres, Juan M

“…The infectious agent responsible for the bovine spongiform encephalopathy (BSE) epidemic in Great Britain is a transmissible spongiform encephalopathy (TSE)…”
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Ovine PRNP untranslated region and promoter haplotype diversity by Saunders, Ginny C, Cawthraw, Saira, Mountjoy, Susan J, Tout, Anna C, Sayers, Anthony R, Hope, Jim, Windl, Otto

“…The diversity and possible contribution of non-coding regions of the prion protein (PrP) gene (PRNP) to transmissible spongiform encephalopathy susceptibility…”
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